| # | Title | Journal | Year | Citations |
|---|
| 1 | New insights into the genetic etiology of Alzheimer’s disease and related dementias | Nature Genetics | 2022 | 700 |
| 2 | Blood-brain barrier dysfunction in parkinsonian midbrain in vivo | Annals of Neurology | 2005 | 650 |
| 3 | Single-agent bevacizumab or lomustine versus a combination of bevacizumab plus lomustine in patients with recurrent glioblastoma (BELOB trial): a randomised controlled phase 2 trial | Lancet Oncology, The | 2014 | 639 |
| 4 | Subthalamic nucleus versus globus pallidus bilateral deep brain stimulation for advanced Parkinson's disease (NSTAPS study): a randomised controlled trial | Lancet Neurology, The | 2013 | 607 |
| 5 | Effects of aspirin plus extended-release dipyridamole versus clopidogrel and telmisartan on disability and cognitive function after recurrent stroke in patients with ischaemic stroke in the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) trial: a double-blind, active and placebo-controlled study | Lancet Neurology, The | 2008 | 310 |
| 6 | Interim results from the CATNON trial (EORTC study 26053-22054) of treatment with concurrent and adjuvant temozolomide for 1p/19q non-co-deleted anaplastic glioma: a phase 3, randomised, open-label intergroup study | Lancet, The | 2017 | 307 |
| 7 | Early predictors of outcome after mild traumatic brain injury (UPFRONT): an observational cohort study | Lancet Neurology, The | 2017 | 249 |
| 8 | Value of 11C-methionine PET in imaging brain tumours and metastases | European Journal of Nuclear Medicine and Molecular Imaging | 2013 | 245 |
| 9 | Optimizing Cutoff Scores for the Barthel Index and the Modified Rankin Scale for Defining Outcome in Acute Stroke Trials | Stroke | 2005 | 243 |
| 10 | Epidemiology, Severity Classification, and Outcome of Moderate and Severe Traumatic Brain Injury: A Prospective Multicenter Study | Journal of Neurotrauma | 2011 | 242 |
| 11 | Extra-Intestinal Manifestations of Familial Adenomatous Polyposis | Annals of Surgical Oncology | 2008 | 223 |
| 12 | Typical cerebral metabolic patterns in neurodegenerative brain diseases | Movement Disorders | 2010 | 221 |
| 13 | Time to Reperfusion and Treatment Effect for Acute Ischemic Stroke | JAMA Neurology | 2016 | 220 |
| 14 | Decreased blood–brain barrier P-glycoprotein function in the progression of Parkinson’s disease, PSP and MSA | Journal of Neural Transmission | 2008 | 217 |
| 15 | Polarised Asymmetric Inheritance of Accumulated Protein Damage in Higher Eukaryotes | PLoS Biology | 2006 | 210 |
| 16 | Dysfunctional astrocytes as key players in the pathogenesis of central nervous system disorders | Journal of the Neurological Sciences | 2008 | 205 |
| 17 | Pulsed high-dose dexamethasone versus standard prednisolone treatment for chronic inflammatory demyelinating polyradiculoneuropathy (PREDICT study): a double-blind, randomised, controlled trial | Lancet Neurology, The | 2010 | 170 |
| 18 | New insights into the pathoanatomy of spinocerebellar ataxia type 3 (Machado–Joseph disease) | Current Opinion in Neurology | 2008 | 165 |
| 19 | Intravenous Alteplase for Stroke | Stroke | 2007 | 163 |
| 20 | Impaired visual processing preceding image recognition in Parkinson's disease patients with visual hallucinations | Brain | 2009 | 163 |
| 21 | Brain Networks Subserving Emotion Regulation and Adaptation after Mild Traumatic Brain Injury | Journal of Neurotrauma | 2016 | 161 |
| 22 | Putative neural substrate of normal and abnormal general movements | Neuroscience and Biobehavioral Reviews | 2007 | 159 |
| 23 | Mutations in DDHD2, Encoding an Intracellular Phospholipase A1, Cause a Recessive Form of Complex Hereditary Spastic Paraplegia | American Journal of Human Genetics | 2012 | 159 |
| 24 | Muscle ultrasound analysis: normal values and differentiation between myopathies and neuropathies | Ultrasound in Medicine and Biology | 2003 | 151 |
| 25 | Stenting versus medical treatment in patients with symptomatic vertebral artery stenosis: a randomised open-label phase 2 trial | Lancet Neurology, The | 2015 | 150 |
| 26 | DNAJC6Mutations Associated With Early‐Onset Parkinson's Disease | Annals of Neurology | 2016 | 148 |
| 27 | Effects of a multifaceted treatment program for executive dysfunction after acquired brain injury on indications of executive functioning in daily life | Journal of the International Neuropsychological Society | 2010 | 143 |
| 28 | Treatment outcome of patients with recurrent glioblastoma multiforme: a retrospective multicenter analysis | Journal of Neuro-Oncology | 2017 | 138 |
| 29 | The Symbol Digit Modalities Test as sentinel test for cognitive impairment in multiple sclerosis | European Journal of Neurology | 2014 | 133 |
| 30 | Social Cognition Impairments in Relation to General Cognitive Deficits, Injury Severity, and Prefrontal Lesions in Traumatic Brain Injury Patients | Journal of Neurotrauma | 2012 | 132 |
| 31 | Adjuvant and concurrent temozolomide for 1p/19q non-co-deleted anaplastic glioma (CATNON; EORTC study 26053-22054): second interim analysis of a randomised, open-label, phase 3 study | Lancet Oncology, The | 2021 | 132 |
| 32 | Whispering dysphonia (DYT4 dystonia) is caused by a mutation in the TUBB4 gene | Annals of Neurology | 2013 | 128 |
| 33 | A novel defect of peroxisome division due to a homozygous non-sense mutation in thePEX11βgene | Journal of Medical Genetics | 2012 | 127 |
| 34 | EuroInf 2: Subthalamic stimulation, apomorphine, and levodopa infusion in Parkinson's disease | Movement Disorders | 2019 | 126 |
| 35 | Targeted Next-Generation Sequencing of a 12.5 Mb Homozygous Region Reveals ANO10 Mutations in Patients with Autosomal-Recessive Cerebellar Ataxia | American Journal of Human Genetics | 2010 | 125 |
| 36 | Dystonia in children and adolescents: a systematic review and a new diagnostic algorithm | Journal of Neurology, Neurosurgery and Psychiatry | 2015 | 124 |
| 37 | Effect of Endovascular Treatment With Medical Management vs Standard Care on Severe Cerebral Venous Thrombosis | JAMA Neurology | 2020 | 122 |
| 38 | Mutations in potassium channel kcnd3 cause spinocerebellar ataxia type 19 | Annals of Neurology | 2012 | 121 |
| 39 | Environmental exposure to pesticides and the risk of Parkinson's disease in the Netherlands | Environment International | 2017 | 121 |
| 40 | Degeneration of the Cerebellum in Huntington's Disease (HD): Possible Relevance for the Clinical Picture and Potential Gateway to Pathological Mechanisms of the Disease Process | Brain Pathology | 2013 | 119 |
| 41 | Increasing Comparability and Utility of Gut Microbiome Studies in Parkinson’s Disease: A Systematic Review | Journal of Parkinson's Disease | 2019 | 117 |
| 42 | Ramsay hunt syndrome: Clinical characterization of progressive myoclonus ataxia caused by GOSR2 mutation | Movement Disorders | 2014 | 113 |
| 43 | Clinical features and predictors for disease natural progression in adults with Pompe disease: a nationwide prospective observational study | Orphanet Journal of Rare Diseases | 2012 | 112 |
| 44 | Unstable TTTTA/TTTCA expansions in MARCH6 are associated with Familial Adult Myoclonic Epilepsy type 3 | Nature Communications | 2019 | 111 |
| 45 | Effects of motor fatigue on human brain activity, an fMRI study | NeuroImage | 2007 | 110 |
| 46 | The Lambert–Eaton myasthenic syndrome 1988–2008: A clinical picture in 97 patients | Journal of Neuroimmunology | 2008 | 107 |
| 47 | Seizures in multiple sclerosis | Epilepsia | 2008 | 104 |
| 48 | Baseline Blood Pressure Effect on the Benefit and Safety of Intra-Arterial Treatment in MR CLEAN (Multicenter Randomized Clinical Trial of Endovascular Treatment of Acute Ischemic Stroke in the Netherlands) | Stroke | 2017 | 104 |
| 49 | Thrombus Permeability Is Associated With Improved Functional Outcome and Recanalization in Patients With Ischemic Stroke | Stroke | 2016 | 103 |
| 50 | Van Buchem disease: Clinical, biochemical, and densitometric features of patients and disease carriers | Journal of Bone and Mineral Research | 2013 | 102 |
