| # | Title | Journal | Year | Citations |
|---|
| 1 | The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism | Journal of Lipid Research | 2013 | 3,292 |
| 2 | Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel | European Heart Journal | 2017 | 2,292 |
| 3 | Environment dominates over host genetics in shaping human gut microbiota | Nature | 2018 | 1,958 |
| 4 | Population-level analysis of gut microbiome variation | Science | 2016 | 1,716 |
| 5 | Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity | Science | 2016 | 1,398 |
| 6 | Early, Accurate Diagnosis and Early Intervention in Cerebral Palsy | JAMA Pediatrics | 2017 | 898 |
| 7 | Low-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the European Atherosclerosis Society Consensus Panel | European Heart Journal | 2020 | 776 |
| 8 | The effect of host genetics on the gut microbiome | Nature Genetics | 2016 | 672 |
| 9 | Familial hypercholesterolaemia in children and adolescents: gaining decades of life by optimizing detection and treatment | European Heart Journal | 2015 | 644 |
| 10 | Evidence Based Selection of Housekeeping Genes | PLoS ONE | 2007 | 617 |
| 11 | Interplay of host genetics and gut microbiota underlying the onset and clinical presentation of inflammatory bowel disease | Gut | 2018 | 590 |
| 12 | Impact of oral vancomycin on gut microbiota, bile acid metabolism, and insulin sensitivity | Journal of Hepatology | 2014 | 475 |
| 13 | Diagnosis and management of acute myeloid leukemia in children and adolescents: recommendations from an international expert panel | Blood | 2012 | 451 |
| 14 | Gut-derived short-chain fatty acids are vividly assimilated into host carbohydrates and lipids | American Journal of Physiology - Renal Physiology | 2013 | 401 |
| 15 | Targeting senescent cells alleviates obesity‐induced metabolic dysfunction | Aging Cell | 2019 | 395 |
| 16 | Beyond intestinal soap—bile acids in metabolic control | Nature Reviews Endocrinology | 2014 | 354 |
| 17 | Inhibition of mTORC1 by Astrin and Stress Granules Prevents Apoptosis in Cancer Cells | Cell | 2013 | 243 |
| 18 | Genetics, Clinical Features, and Long-Term Outcome of Noncompaction Cardiomyopathy | Journal of the American College of Cardiology | 2018 | 242 |
| 19 | Regulatory enzymes of mitochondrial β‐oxidation as targets for treatment of the metabolic syndrome | Obesity Reviews | 2010 | 229 |
| 20 | Abnormal Liver Function Tests in Patients With COVID‐19: Relevance and Potential Pathogenesis | Hepatology | 2020 | 221 |
| 21 | High-fat diet induced obesity primes inflammation in adipose tissue prior to liver in C57BL/6j mice | Aging | 2015 | 201 |
| 22 | COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A | Molecular Biology of the Cell | 2015 | 200 |
| 23 | Lymphocyte-Derived Exosomal MicroRNAs Promote Pancreatic β Cell Death and May Contribute to Type 1 Diabetes Development | Cell Metabolism | 2019 | 200 |
| 24 | A 12‐Week Aerobic Exercise Program Reduces Hepatic Fat Accumulation and Insulin Resistance in Obese, Hispanic Adolescents | Obesity | 2010 | 198 |
| 25 | Global phylogeography and ancient evolution of the widespread human gut virus crAssphage | Nature Microbiology | 2019 | 184 |
| 26 | VEGFB/VEGFR1-Induced Expansion of Adipose Vasculature Counteracts Obesity and Related Metabolic Complications | Cell Metabolism | 2016 | 180 |
| 27 | Activation of the Liver X Receptor Stimulates Trans-intestinal Excretion of Plasma Cholesterol | Journal of Biological Chemistry | 2009 | 178 |
| 28 | In Utero Undernutrition in Male Mice Programs Liver Lipid Metabolism in the Second-Generation Offspring Involving Altered Lxra DNA Methylation | Cell Metabolism | 2014 | 178 |
| 29 | Support for the global feasibility of the Ages and Stages Questionnaire as developmental screener | Early Human Development | 2009 | 177 |
| 30 | Sodium taurocholate cotransporting polypeptide (SLC10A1) deficiency: Conjugated hypercholanemia without a clear clinical phenotype | Hepatology | 2015 | 169 |
| 31 | The long-term genetic stability and individual specificity of the human gut microbiome | Cell | 2021 | 166 |
| 32 | CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL | Nature Communications | 2016 | 165 |
| 33 | Improved glycemic control with colesevelam treatment in patients with type 2 diabetes is not directly associated with changes in bile acid metabolism | Hepatology | 2010 | 163 |
| 34 | Association of IL33–IL-1 receptor–like 1 (IL1RL1) pathway polymorphisms with wheezing phenotypes and asthma in childhood | Journal of Allergy and Clinical Immunology | 2014 | 162 |
| 35 | Categorizing Neonatal Deaths: A Cross-Cultural Study in the United States, Canada, and The Netherlands | Journal of Pediatrics | 2010 | 154 |
| 36 | The NADPH oxidase Nox4 has anti-atherosclerotic functions | European Heart Journal | 2015 | 150 |
| 37 | Early Intervention for Children Aged 0 to 2 Years With or at High Risk of Cerebral Palsy | JAMA Pediatrics | 2021 | 147 |
| 38 | Two-Step Senescence-Focused Cancer Therapies | Trends in Cell Biology | 2018 | 145 |
| 39 | Fenofibrate Simultaneously Induces Hepatic Fatty Acid Oxidation, Synthesis, and Elongation in Mice | Journal of Biological Chemistry | 2009 | 141 |
| 40 | Peak bone mineral density, lean body mass and fractures | Bone | 2010 | 140 |
| 41 | PEX2 is the E3 ubiquitin ligase required for pexophagy during starvation | Journal of Cell Biology | 2016 | 137 |
| 42 | Strength Exercise Improves Muscle Mass and Hepatic Insulin Sensitivity in Obese Youth | Medicine and Science in Sports and Exercise | 2010 | 136 |
| 43 | Malnutrition-associated liver steatosis and ATP depletion is caused by peroxisomal and mitochondrial dysfunction | Journal of Hepatology | 2016 | 133 |
| 44 | Integrated Network Analysis Reveals an Association between Plasma Mannose Levels and Insulin Resistance | Cell Metabolism | 2016 | 133 |
| 45 | Biliary Bicarbonate, pH, and Glucose Are Suitable Biomarkers of Biliary Viability During Ex Situ Normothermic Machine Perfusion of Human Donor Livers | Transplantation | 2019 | 133 |
| 46 | Preeclampsia is Associated with Lower Percentages of Regulatory T Cells in Maternal Blood | Hypertension in Pregnancy | 2009 | 132 |
| 47 | The liver X-receptor gene promoter is hypermethylated in a mouse model of prenatal protein restriction | American Journal of Physiology - Regulatory Integrative and Comparative Physiology | 2010 | 131 |
| 48 | Emerging roles of the intestine in control of cholesterol metabolism | World Journal of Gastroenterology | 2006 | 130 |
| 49 | FXR and PXR: Potential therapeutic targets in cholestasis | Journal of Steroid Biochemistry and Molecular Biology | 2012 | 127 |
| 50 | High Fat Feeding Induces Hepatic Fatty Acid Elongation in Mice | PLoS ONE | 2009 | 126 |
