# | Title | Journal | Year | Citations |
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1 | Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 | Cell Death and Differentiation | 2018 | 4,036 |
2 | Natural and synthetic non-peptide antigens recognized by human γδ T cells | Nature | 1995 | 959 |
3 | Acute stimulation of glucose metabolism in mice by leptin treatment | Nature | 1997 | 676 |
4 | S100 proteins in cancer | Nature Reviews Cancer | 2015 | 622 |
5 | Molecular Insights into Aminoglycoside Action and Resistance | Chemical Reviews | 2005 | 599 |
6 | Cofilin Promotes Actin Polymerization and Defines the Direction of Cell Motility | Science | 2004 | 596 |
7 | Type VI secretion apparatus and phage tail-associated protein complexes share a common evolutionary origin | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 576 |
8 | GANGLIOSIDES OF HUMAN MYELIN: SIALOSYLGALACTOSYLCERAMIDE (G7) AS A MAJOR COMPONENT | Journal of Neurochemistry | 1973 | 561 |
9 | Periodic Lamellipodial Contractions Correlate with Rearward Actin Waves | Cell | 2004 | 536 |
10 | Structure and functions of the GNAT superfamily of acetyltransferases | Archives of Biochemistry and Biophysics | 2005 | 529 |
11 | Meropenem-Clavulanate Is Effective Against Extensively Drug-Resistant Mycobacterium tuberculosis | Science | 2009 | 477 |
12 | Cardiac and adipose tissue abnormalities but not diabetes in mice deficient in GLUT4 | Nature | 1995 | 446 |
13 | Crystal structure and function of the isoniazid target of Mycobacterium tuberculosis | Science | 1995 | 428 |
14 | Crystal Structure of Recombinant Farnesyl Diphosphate Synthase at 2.6-.ANG. Resolution | Biochemistry | 1994 | 415 |
15 | Identification of a second aryl phosphate-binding site in protein-tyrosine phosphatase 1B: A paradigm for inhibitor design | Proceedings of the National Academy of Sciences of the United States of America | 1997 | 412 |
16 | Enzymic Characterization of the Target for Isoniazid in Mycobacterium tuberculosis | Biochemistry | 1995 | 390 |
17 | Regulation of proteasome activity in health and disease | Biochimica Et Biophysica Acta - Molecular Cell Research | 2014 | 377 |
18 | Increasing the Efficacy of Bioorthogonal Click Reactions for Bioconjugation: A Comparative Study | Angewandte Chemie - International Edition | 2011 | 370 |
19 | The PRMT5 arginine methyltransferase: many roles in development, cancer and beyond | Cellular and Molecular Life Sciences | 2015 | 364 |
20 | Peptide-Based Vaccines: Current Progress and Future Challenges | Chemical Reviews | 2020 | 352 |
21 | Molecular mechanisms of nonmuscle myosin-II regulation | Current Opinion in Cell Biology | 1999 | 338 |
22 | A Left-Handed Parallel beta Helix in the Structure of UDP-N-Acetylglucosamine Acyltransferase | Science | 1995 | 333 |
23 | Regulation of product chain length by isoprenyl diphosphate synthases | Proceedings of the National Academy of Sciences of the United States of America | 1996 | 331 |
24 | Structural and Functional Analysis of the Costimulatory Receptor Programmed Death-1 | Immunity | 2004 | 331 |
25 | GLUT4 heterozygous knockout mice develop muscle insulin resistance and diabetes | Nature Medicine | 1997 | 326 |
26 | Nomenclature of the GLUT/SLC2A family of sugar/polyol transport facilitators | American Journal of Physiology - Endocrinology and Metabolism | 2002 | 325 |
27 | Structural basis for co-stimulation by the human CTLA-4/B7-2 complex | Nature | 2001 | 323 |
28 | Improved Insulin Sensitivity and Resistance to Weight Gain in Mice Null for the Ahsg Gene | Diabetes | 2002 | 320 |
29 | QUAKING MOUSE: ISOLATION AND CHARACTERIZATION OF MYELIN PROTEIN | Journal of Neurochemistry | 1971 | 307 |
30 | Immune responses to SARS-CoV-2 infection in hospitalized pediatric and adult patients | Science Translational Medicine | 2020 | 298 |
31 | Glucagon Receptor Knockout Prevents Insulin-Deficient Type 1 Diabetes in Mice | Diabetes | 2011 | 294 |
32 | Purification and Biological Activity of Thymosin, a Hormone of the Thymus Gland | Proceedings of the National Academy of Sciences of the United States of America | 1972 | 293 |
33 | Chemistry of Gene Silencing: The Mechanism of NAD+-Dependent Deacetylation Reactions | Biochemistry | 2001 | 293 |
34 | S100A4, a Mediator of Metastasis | Journal of Biological Chemistry | 2006 | 293 |
35 | New perspectives for targeting RAF kinase in human cancer | Nature Reviews Cancer | 2017 | 285 |
36 | ENZYMATIC TRANSITION STATES AND TRANSITION STATE ANALOG DESIGN | Annual Review of Biochemistry | 1998 | 279 |
37 | Durable antitumor responses to CD47 blockade require adaptive immune stimulation | Proceedings of the National Academy of Sciences of the United States of America | 2016 | 272 |
38 | A Fluoroquinolone Resistance Protein from Mycobacterium tuberculosis That Mimics DNA | Science | 2005 | 264 |
39 | A metabolic pathway for bile acid dehydroxylation by the gut microbiome | Nature | 2020 | 262 |
40 | Intracellular Binding and Transport of Hormones and Xenobiotics by Glutathiones-Transferases | Drug Metabolism Reviews | 1988 | 258 |
41 | Opioid and Opiate Immunoregulatory Processes | Critical Reviews in Immunology | 1996 | 258 |
42 | One-Third-the-Sites Transition-State Inhibitors for Purine Nucleoside Phosphorylase† | Biochemistry | 1998 | 254 |
43 | Structure-based activity prediction for an enzyme of unknown function | Nature | 2007 | 249 |
44 | Bright monomeric near-infrared fluorescent proteins as tags and biosensors for multiscale imaging | Nature Communications | 2016 | 249 |
45 | Crystal Structure of the Mycobacterium tuberculosis Enoyl-ACP Reductase, InhA, in Complex with NAD+ and a C16 Fatty Acyl Substrate | Journal of Biological Chemistry | 1999 | 248 |
46 | Localization of types I, III and IV collagen mRNAs in rat heart cells by in situ hybridization | Journal of Molecular and Cellular Cardiology | 1989 | 237 |
47 | Synergies and Coincidence Requirements between NO, cGMP, and Ca2+ in the Induction of Cerebellar Long-Term Depression | Neuron | 1997 | 237 |
48 | The activity status of cofilin is directly related to invasion, intravasation, and metastasis of mammary tumors | Journal of Cell Biology | 2006 | 236 |
49 | Enzymatic transition states and dynamic motion in barrier crossing | Nature Chemical Biology | 2009 | 236 |
50 | Essential functions and actin-binding surfaces of yeast cofilin revealed by systematic mutagenesis | EMBO Journal | 1997 | 235 |