Molecular aspects of bacterial pH sensing and homeostasis | Nature Reviews Microbiology | 2011 | 577 |
Clinical Pharmacogenetics Implementation Consortium guidelines for cytochrome P450-2C19 (CYP2C19) genotype and clopidogrel therapy | Clinical Pharmacology and Therapeutics | 2011 | 346 |
A critical role for IGF-II in memory consolidation and enhancement | Nature | 2011 | 306 |
Cognitive dysfunction in depression: neurocircuitry and new therapeutic strategies | Neurobiology of Learning and Memory | 2011 | 222 |
IκB kinase regulates social defeat stress-induced synaptic and behavioral plasticity | Journal of Neuroscience | 2011 | 214 |
Maternal cannabis use alters ventral striatal dopamine D2 gene regulation in the offspring | Biological Psychiatry | 2011 | 153 |
Critical role for stromal interaction molecule 1 in cardiac hypertrophy | Circulation | 2011 | 124 |
The highs and lows of cannabinoid receptor expression in disease: mechanisms and their therapeutic implications | Pharmacological Reviews | 2011 | 120 |
AT1R-CB₁R heteromerization reveals a new mechanism for the pathogenic properties of angiotensin II | EMBO Journal | 2011 | 109 |
Exploring a role for heteromerization in GPCR signalling specificity | Biochemical Journal | 2011 | 107 |
Role for mTOR signaling and neuronal activity in morphine-induced adaptations in ventral tegmental area dopamine neurons | Neuron | 2011 | 99 |
Specific role of VTA dopamine neuronal firing rates and morphology in the reversal of anxiety-related, but not depression-related behavior in the ClockΔ19 mouse model of mania | Neuropsychopharmacology | 2011 | 91 |
An RNA pyrophosphohydrolase triggers 5'-exonucleolytic degradation of mRNA in Bacillus subtilis | Molecular Cell | 2011 | 89 |
Role of systems pharmacology in understanding drug adverse events | Wiley Interdisciplinary Reviews: Systems Biology and Medicine | 2011 | 83 |
Quantification of repolarization reserve to understand interpatient variability in the response to proarrhythmic drugs: a computational analysis | Heart Rhythm | 2011 | 81 |
Molecular mechanisms of maternal cannabis and cigarette use on human neurodevelopment | European Journal of Neuroscience | 2011 | 80 |
Haploinsufficiency of Gtf2i, a gene deleted in Williams Syndrome, leads to increases in social interactions | Autism Research | 2011 | 79 |
Introduction to network analysis in systems biology | Science Signaling | 2011 | 79 |
Potentiation of μ-opioid receptor-mediated signaling by ketamine | Journal of Neurochemistry | 2011 | 72 |
G protein-coupled receptor heteromerization: a role in allosteric modulation of ligand binding | Molecular Pharmacology | 2011 | 71 |
Cannabidiol causes activated hepatic stellate cell death through a mechanism of endoplasmic reticulum stress-induced apoptosis | Cell Death and Disease | 2011 | 70 |
Recovery of cardiac calcium release is controlled by sarcoplasmic reticulum refilling and ryanodine receptor sensitivity | Cardiovascular Research | 2011 | 69 |
Genome of alkaliphilic Bacillus pseudofirmus OF4 reveals adaptations that support the ability to grow in an external pH range from 7.5 to 11.4 | Environmental Microbiology | 2011 | 63 |
Synaptic stimulation of mTOR is mediated by Wnt signaling and regulation of glycogen synthetase kinase-3 | Journal of Neuroscience | 2011 | 62 |
Phosphatidylinositol-4,5-bisphosphate regulates epidermal growth factor receptor activation | Pflugers Archiv European Journal of Physiology | 2011 | 61 |