| # | Title | Journal | Year | Citations |
|---|
| 1 | Diagnostic criteria for multiple sclerosis: 2010 Revisions to the McDonald criteria | Annals of Neurology | 2011 | 8,001 |
| 2 | Movement Disorder Society‐sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS‐UPDRS): Scale presentation and clinimetric testing results | Movement Disorders | 2008 | 4,796 |
| 3 | A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease | Annals of Neurology | 2003 | 1,450 |
| 4 | Astrocyte-Neuron Lactate Transport Is Required for Long-Term Memory Formation | Cell | 2011 | 1,285 |
| 5 | Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS): Process, format, and clinimetric testing plan | Movement Disorders | 2007 | 1,097 |
| 6 | Diagnostic procedures for Parkinson's disease dementia: Recommendations from the movement disorder society task force | Movement Disorders | 2007 | 885 |
| 7 | International multicenter pilot study of the first comprehensive self-completed nonmotor symptoms questionnaire for Parkinson's disease: The NMSQuest study | Movement Disorders | 2006 | 865 |
| 8 | Identification of a serotonin/glutamate receptor complex implicated in psychosis | Nature | 2008 | 739 |
| 9 | Hallucinogens Recruit Specific Cortical 5-HT2A Receptor-Mediated Signaling Pathways to Affect Behavior | Neuron | 2007 | 692 |
| 10 | The Beclin 1–VPS34 complex – at the crossroads of autophagy and beyond | Trends in Cell Biology | 2010 | 687 |
| 11 | The scientific and clinical basis for the treatment of Parkinson disease (2009) | Neurology | 2009 | 685 |
| 12 | Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome | Nature | 2010 | 672 |
| 13 | Von Hippel–Lindau disease maps to the region of chromosome 3 associated with renal cell carcinoma | Nature | 1988 | 629 |
| 14 | Understanding cell death in parkinson's disease | Annals of Neurology | 1998 | 605 |
| 15 | Gene delivery of AAV2-neurturin for Parkinson's disease: a double-blind, randomised, controlled trial | Lancet Neurology, The | 2010 | 589 |
| 16 | An algorithm (decision tree) for the management of Parkinson’s disease (2001): | Neurology | 2001 | 565 |
| 17 | Safety and tolerability of intraputaminal delivery of CERE-120 (adeno-associated virus serotype 2–neurturin) to patients with idiopathic Parkinson's disease: an open-label, phase I trial | Lancet Neurology, The | 2008 | 529 |
| 18 | Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication | Molecular Autism | 2010 | 521 |
| 19 | Wdr5 Mediates Self-Renewal and Reprogramming via the Embryonic Stem Cell Core Transcriptional Network | Cell | 2011 | 521 |
| 20 | Failure of the ubiquitin–proteasome system in Parkinson's disease | Nature Reviews Neuroscience | 2001 | 490 |
| 21 | Continuous dopamine-receptor treatment of Parkinson's disease: scientific rationale and clinical implications | Lancet Neurology, The | 2006 | 461 |
| 22 | Fetal nigral transplantation as a therapy for Parkinson's disease | Trends in Neurosciences | 1996 | 455 |
| 23 | Accuracy and calibration of commercial oligonucleotide and custom cDNA microarrays | Nucleic Acids Research | 2002 | 453 |
| 24 | Volume of ventricular blood is an important determinant of outcome in supratentorial intracerebral hemorrhage | Critical Care Medicine | 1999 | 442 |
| 25 | Ambulatory monitoring of freezing of gait in Parkinson's disease | Journal of Neuroscience Methods | 2008 | 424 |
| 26 | Manganese-Induced Parkinsonism and Parkinson's Disease | Annals of the New York Academy of Sciences | 2004 | 423 |
| 27 | Antiphospholipid Antibodies and Subsequent Thrombo-occlusive Events in Patients With Ischemic Stroke | JAMA - Journal of the American Medical Association | 2004 | 405 |
| 28 | Levodopa motor complications in Parkinson's disease | Trends in Neurosciences | 2000 | 393 |
| 29 | Formation and maintenance of Alzheimer's disease β-amyloid plaques in the absence of microglia | Nature Neuroscience | 2009 | 390 |
| 30 | Mutations in the THAP1 gene are responsible for DYT6 primary torsion dystonia | Nature Genetics | 2009 | 384 |
| 31 | Cortical 5-HT2A Receptor Signaling Modulates Anxiety-Like Behaviors in Mice | Science | 2006 | 375 |
| 32 | Alterations in lysosomal and proteasomal markers in Parkinson's disease: Relationship to alpha-synuclein inclusions | Neurobiology of Disease | 2009 | 360 |
| 33 | A Phase 1/2 Clinical Trial of Enzyme Replacement in Fabry Disease: Pharmacokinetic, Substrate Clearance, and Safety Studies | American Journal of Human Genetics | 2001 | 350 |
| 34 | Subthalamic nucleus‐mediated excitotoxicity in parkinson's disease: A target for neuroprotection | Annals of Neurology | 1998 | 344 |
| 35 | Apoptosis in Parkinson's disease: Signals for neuronal degradation | Annals of Neurology | 2003 | 337 |
| 36 | Levodopa in the treatment of Parkinson's disease: Current controversies | Movement Disorders | 2004 | 331 |
| 37 | Parkinson's Disease and Alpha Synuclein: Is Parkinson's Disease a Prion‐Like Disorder? | Movement Disorders | 2013 | 320 |
| 38 | The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease | Scientific Data | 2018 | 320 |
| 39 | Enhanced Striatal Dopamine Transmission and Motor Performance with LRRK2 Overexpression in Mice Is Eliminated by Familial Parkinson's Disease Mutation G2019S | Journal of Neuroscience | 2010 | 309 |
| 40 | Exome Sequencing Reveals De Novo WDR45 Mutations Causing a Phenotypically Distinct, X-Linked Dominant Form of NBIA | American Journal of Human Genetics | 2012 | 309 |
| 41 | Visual deficits related to dopamine deficiency in experimental animals and Parkinson's disease patients | Trends in Neurosciences | 1990 | 304 |
| 42 | Interaction of the body, head, and eyes during walking and turning | Experimental Brain Research | 2001 | 299 |
| 43 | Extracellular proteolysis by matrix metalloproteinase-9 drives dendritic spine enlargement and long-term potentiation coordinately | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 288 |
| 44 | Accuracy assessment of the processed SRTM-based elevation data by CGIAR using field data from USA and Thailand and its relation to the terrain characteristics | Remote Sensing of Environment | 2006 | 283 |
| 45 | Mutations in GNAL cause primary torsion dystonia | Nature Genetics | 2013 | 281 |
| 46 | Lewy-body formation is an aggresome-related process: a hypothesis | Lancet Neurology, The | 2004 | 278 |
| 47 | Impairment of the ubiquitin-proteasome system causes dopaminergic cell death and inclusion body formation in ventral mesencephalic cultures | Journal of Neurochemistry | 2002 | 272 |
| 48 | Decoding the Signaling of a GPCR Heteromeric Complex Reveals a Unifying Mechanism of Action of Antipsychotic Drugs | Cell | 2011 | 271 |
| 49 | Alloxan-induced diabetes—evidence for hydroxyl radical as a cytotoxic intermediate | Biochemical Pharmacology | 1976 | 254 |
| 50 | Transcriptome Fingerprints Distinguish Hallucinogenic and Nonhallucinogenic 5-Hydroxytryptamine 2A Receptor Agonist Effects in Mouse Somatosensory Cortex | Journal of Neuroscience | 2003 | 252 |
