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Top Articles

#TitleJournalYearCitations
1SiO2 nanoparticles induce cytotoxicity and protein expression alteration in HaCaT cellsParticle and Fibre Toxicology2010311
2MiR-454-3p-Mediated Wnt/β-catenin Signaling Antagonists Suppression Promotes Breast Cancer MetastasisTheranostics2019103
3SOX9 drives the epithelial–mesenchymal transition in non-small-cell lung cancer through the Wnt/β-catenin pathwayJournal of Translational Medicine201988
4Clinical significance of SOX9 in human non-small cell lung cancer progression and overall patient survivalJournal of Experimental and Clinical Cancer Research201266
5G9a coordinates with the RPA complex to promote DNA damage repair and cell survivalProceedings of the National Academy of Sciences of the United States of America201764
6Downregulation of SIRT7 by 5-fluorouracil induces radiosensitivity in human colorectal cancerTheranostics201759
7Destabilization of linker histone H1.2 is essential for ATM activation and DNA damage repairCell Research201859
8MiR-125a-5p ameliorates monocrotaline-induced pulmonary arterial hypertension by targeting the TGF-β1 and IL-6/STAT3 signaling pathwaysExperimental and Molecular Medicine201856
9Histone H1 acetylation at lysine 85 regulates chromatin condensation and genome stability upon DNA damageNucleic Acids Research201856
10Differentiated regulation of immune-response related genes between LUAD and LUSC subtypes of lung cancersOncotarget201754
11Serine-arginine protein kinase 1 promotes a cancer stem cell-like phenotype through activation of Wnt/β-catenin signalling in NSCLCJournal of Pathology201641
12Solo Smart Fluorogenic Probe for Potential Cancer Diagnosis and Tracking in Vivo Tumorous Lymphatic Systems via Distinct Emission SignalsAnalytical Chemistry202040
13MiR-328 targeting PIM-1 inhibits proliferation and migration of pulmonary arterial smooth muscle cells in PDGFBB signaling pathwayOncotarget201638
14CBP mediated DOT1L acetylation confers DOT1L stability and promotes cancer metastasisTheranostics202031
15Mining of high utility-probability sequential patterns from uncertain databasesPLoS ONE201728
16Mechanisms controlling the anti-neoplastic functions of FoxO proteinsSeminars in Cancer Biology201828
17Cancer-associated fibroblasts employ NUFIP1-dependent autophagy to secrete nucleosides and support pancreatic tumor growthNature Cancer202228
18Use of Random Amplified Polymorphic DNA Analysis for Economically Important Food CropsJournal of Integrative Plant Biology200726
19p53 cooperates with SIRT6 to regulate cardiolipin de novo biosynthesisCell Death and Disease201826
20Parkin facilitates proteasome inhibitor-induced apoptosis via suppression of NF-κB activity in hepatocellular carcinomaCell Death and Disease201925
21Pains and Gains from China’s Experiences with Emerging Epidemics: From SARS to H7N9BioMed Research International201623
22GOLPH3/CKAP4 promotes metastasis and tumorigenicity by enhancing the secretion of exosomal WNT3A in non-small-cell lung cancerCell Death and Disease202122
23Cerebral malaria induced by plasmodium falciparum: clinical features, pathogenesis, diagnosis, and treatmentFrontiers in Cellular and Infection Microbiology022
24Specific Degradation of Endogenous Tau Protein and Inhibition of Tau Fibrillation by Tanshinone IIA through the Ubiquitin–Proteasome PathwayJournal of Agricultural and Food Chemistry202020
25SRPK1/AKT axis promotes oxaliplatin-induced anti-apoptosis via NF-κB activation in colon cancerJournal of Translational Medicine202119
26A novel acridine derivative, LS-1-10 inhibits autophagic degradation and triggers apoptosis in colon cancer cellsCell Death and Disease201718
27Interleukin‑6 signaling blockade treatment for cytokine release syndrome in COVID‑19 (Review)Experimental and Therapeutic Medicine202017
28Aurora kinase inhibitor tozasertib suppresses mast cell activation in vitro and in vivoBritish Journal of Pharmacology202014
29The Emerging Roles of the RNA Binding Protein QKI in Cardiovascular Development and FunctionFrontiers in Cell and Developmental Biology202114
30FAK inhibitor PF-431396 suppresses IgE-mediated mast cell activation and allergic inflammation in miceBiochemical Pharmacology202113
31CDK4/6 inhibitor palbociclib suppresses IgE-mediated mast cell activationJournal of Translational Medicine201911
32MHC class II in renal tubules plays an essential role in renal fibrosisCellular and Molecular Immunology202111
33Golgi phosphoprotein 3 induces autophagy and epithelial–mesenchymal transition to promote metastasis in colon cancerCell Death Discovery202210
34Antipsychotic agent pimozide promotes reversible proliferative suppression by inducing cellular quiescence in liver cancerOncology Reports20199
35Prognostic role of PHYH for overall survival (OS) in clear cell renal cell carcinoma (ccRCC)European Journal of Medical Research20219
36LncRNA CTBP1-DT-encoded microprotein DDUP sustains DNA damage response signalling to trigger dual DNA repair mechanismsNucleic Acids Research20229
37Identification of Der f 23 as a new major allergen of Dermatophagoides farinaeMolecular Medicine Reports20197
38Enhanced sensitivity of capture IgE‑ELISA based on a recombinant Der f 1/2 fusion protein for the detection of IgE antibodies targeting house dust mite allergensMolecular Medicine Reports20197
39The antipsychotic drug pimozide inhibits IgE-mediated mast cell degranulation and migrationInternational Immunopharmacology20207
40Cell phone-based online biochemistry and molecular biology medical education curriculumMedical Education Online20176
41Histone lysine modifying enzymes and their critical roles in DNA double-strand break repairDNA Repair20216
42Flavoring agent dihydrocoumarin alleviates IgE-mediated mast cell activation and allergic inflammationFood and Function20226
43Regulation of p53 acetylationScience China Life Sciences20175
44Helicobacter pylori infection induced genome instability and gastric cancerGenome Instability & Disease20204
45Ribonuclease T2 from Aspergillus fumigatus promotes T helper type 2 responses through M2 polarization of macrophagesInternational Journal of Molecular Medicine20204
46Transcription Factors From Haematococcus pluvialis Involved in the Regulation of Astaxanthin Biosynthesis Under High Light-Sodium Acetate StressFrontiers in Bioengineering and Biotechnology20214
47Intervening pyruvate carboxylase stunts tumor growth by strengthening anti-tumor actions of tumor-associated macrophagesSignal Transduction and Targeted Therapy20224
48Identification of immunodominant IgE epitopes of the major house dust mite allergen Der f 24International Journal of Molecular Medicine20193
49Chromosome-level assembly of Dermatophagoides farinae genome and transcriptome reveals two novel allergens Der f 37 and Der f 39World Allergy Organization Journal20213
50Plant-Derived Molecule 4-Methylumbelliferone Suppresses FcεRI-Mediated Mast Cell Activation and Allergic InflammationMolecules20223