| # | Title | Journal | Year | Citations |
|---|
| 1 | The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic | Nature Reviews Gastroenterology and Hepatology | 2014 | 5,773 |
| 2 | Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 | Cell Death and Differentiation | 2018 | 4,036 |
| 3 | ESPEN guideline on clinical nutrition in the intensive care unit | Clinical Nutrition | 2019 | 1,610 |
| 4 | Clinical and biological implications of driver mutations in myelodysplastic syndromes | Blood | 2013 | 1,562 |
| 5 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 6 | Profits and pandemics: prevention of harmful effects of tobacco, alcohol, and ultra-processed food and drink industries | Lancet, The | 2013 | 1,248 |
| 7 | The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic Neoplasms | Leukemia | 2022 | 1,211 |
| 8 | A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants | Nature Genetics | 2016 | 1,167 |
| 9 | Clearance systems in the brain—implications for Alzheimer disease | Nature Reviews Neurology | 2015 | 1,127 |
| 10 | Association analysis identifies 65 new breast cancer risk loci | Nature | 2017 | 1,099 |
| 11 | Omega‐3 polyunsaturated fatty acids and inflammatory processes: nutrition or pharmacology? | British Journal of Clinical Pharmacology | 2013 | 950 |
| 12 | Microglial priming in neurodegenerative disease | Nature Reviews Neurology | 2014 | 827 |
| 13 | Anaphylaxis: guidelines from the European Academy of Allergy and Clinical Immunology | Allergy: European Journal of Allergy and Clinical Immunology | 2014 | 809 |
| 14 | Review: Activation patterns of microglia and their identification in the human brain | Neuropathology and Applied Neurobiology | 2013 | 792 |
| 15 | Global Epidemiology of Pediatric Severe Sepsis: The Sepsis Prevalence, Outcomes, and Therapies Study | American Journal of Respiratory and Critical Care Medicine | 2015 | 762 |
| 16 | ESPEN expert group recommendations for action against cancer-related malnutrition | Clinical Nutrition | 2017 | 758 |
| 17 | Treatable traits: toward precision medicine of chronic airway diseases | European Respiratory Journal | 2016 | 746 |
| 18 | Ranibizumab versus Bevacizumab to Treat Neovascular Age-related Macular Degeneration | Ophthalmology | 2012 | 724 |
| 19 | Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes | American Journal of Human Genetics | 2019 | 711 |
| 20 | The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics | Nature Reviews Gastroenterology and Hepatology | 2021 | 701 |
| 21 | New insights into the genetic etiology of Alzheimer’s disease and related dementias | Nature Genetics | 2022 | 700 |
| 22 | Prevalence of common food allergies in Europe: a systematic review and meta-analysis | Allergy: European Journal of Allergy and Clinical Immunology | 2014 | 689 |
| 23 | Retinal gene therapy in patients with choroideremia: initial findings from a phase 1/2 clinical trial | Lancet, The | 2014 | 689 |
| 24 | Practical recommendations for the management of diabetes in patients with COVID-19 | Lancet Diabetes and Endocrinology,the | 2020 | 680 |
| 25 | Cancer classification using the Immunoscore: a worldwide task force | Journal of Translational Medicine | 2012 | 676 |
| 26 | Randomized Trial of Complete Versus Lesion-Only Revascularization in Patients Undergoing Primary Percutaneous Coronary Intervention for STEMI and Multivessel Disease | Journal of the American College of Cardiology | 2015 | 662 |
| 27 | Mechanisms of Action of (n-3) Fatty Acids, | Journal of Nutrition | 2012 | 648 |
| 28 | Estimated glomerular filtration rate and albuminuria for prediction of cardiovascular outcomes: a collaborative meta-analysis of individual participant data | Lancet Diabetes and Endocrinology,the | 2015 | 604 |
| 29 | Low-grade inflammation, diet composition and health: current research evidence and its translation | British Journal of Nutrition | 2015 | 600 |
| 30 | Chronic inflammation induces telomere dysfunction and accelerates ageing in mice | Nature Communications | 2014 | 596 |
| 31 | Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect against Viral Infections | Nutrients | 2020 | 585 |
| 32 | Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis | Nature Genetics | 2015 | 529 |
| 33 | Genome-wide Analyses Identify KIF5A as a Novel ALS Gene | Neuron | 2018 | 517 |
| 34 | The International Consensus Classification of Mature Lymphoid Neoplasms: a report from the Clinical Advisory Committee | Blood | 2022 | 512 |
| 35 | Evidence-based pharmacological treatment of anxiety disorders, post-traumatic stress disorder and obsessive-compulsive disorder: A revision of the 2005 guidelines from the British Association for Psychopharmacology | Journal of Psychopharmacology | 2014 | 511 |
| 36 | Nutrient enrichment can increase the susceptibility of reef corals to bleaching | Nature Climate Change | 2013 | 510 |
| 37 | Aberrations of EZH2 in Cancer | Clinical Cancer Research | 2011 | 503 |
| 38 | A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations | Nature Genetics | 2014 | 497 |
| 39 | Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis | Nature Genetics | 2016 | 494 |
| 40 | Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer | Nature Genetics | 2013 | 493 |
| 41 | Biofabrication of bone tissue: approaches, challenges and translation for bone regeneration | Biomaterials | 2016 | 483 |
| 42 | Coffee consumption and health: umbrella review of meta-analyses of multiple health outcomes | BMJ: British Medical Journal | 2017 | 477 |
| 43 | Germline mutations in RAD51D confer susceptibility to ovarian cancer | Nature Genetics | 2011 | 460 |
| 44 | Energy balance and obesity: what are the main drivers? | Cancer Causes and Control | 2017 | 455 |
| 45 | COVID-19 and medical education | Lancet Infectious Diseases, The | 2020 | 455 |
| 46 | Vascular dysfunction—The disregarded partner of Alzheimer's disease | Alzheimer's and Dementia | 2019 | 454 |
| 47 | Obesity, Inflammation, Toll-Like Receptor 4 and Fatty Acids | Nutrients | 2018 | 452 |
| 48 | CSF drains directly from the subarachnoid space into nasal lymphatics in the rat. Anatomy, histology and immunological significance | Neuropathology and Applied Neurobiology | 1993 | 434 |
| 49 | Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort | European Respiratory Journal | 2015 | 434 |
| 50 | Defining a Healthy Diet: Evidence for the Role of Contemporary Dietary Patterns in Health and Disease | Nutrients | 2020 | 433 |
