| # | Title | Journal | Year | Citations |
|---|
| 1 | The p66shc adaptor protein controls oxidative stress response and life span in mammals | Nature | 1999 | 1,619 |
| 2 | Pten is essential for embryonic development and tumour suppression | Nature Genetics | 1998 | 1,428 |
| 3 | Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies | Nature Genetics | 1998 | 1,361 |
| 4 | BRCA1 mutations in primary breast and ovarian carcinomas | Science | 1994 | 1,167 |
| 5 | The Multiple Roles of PTEN in Tumor Suppression | Cell | 2000 | 1,064 |
| 6 | The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds | Nature Genetics | 1996 | 775 |
| 7 | The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation | Nature Genetics | 1997 | 753 |
| 8 | Familial colorectal cancer in Ashkenazim due to a hypermutable tract in APC | Nature Genetics | 1997 | 630 |
| 9 | Therapeutic haemoglobin synthesis in β-thalassaemic mice expressing lentivirus-encoded human β-globin | Nature | 2000 | 581 |
| 10 | Distinct interactions of PML-RARα and PLZF-RARα with co-repressors determine differential responses to RA in APL | Nature Genetics | 1998 | 566 |
| 11 | Pten and p27KIP1 cooperate in prostate cancer tumor suppression in the mouse | Nature Genetics | 2001 | 458 |
| 12 | The carrier frequency of the BRCA2 6174delT mutation among Ashkenazi Jewish individuals is approximately 1% | Nature Genetics | 1996 | 375 |
| 13 | Clonal populations of hematopoietic cells with paroxysmal nocturnal hemoglobinuria genotype and phenotype are present in normal individuals | Proceedings of the National Academy of Sciences of the United States of America | 1999 | 364 |
| 14 | Acute leukemia with promyelocytic features in PML/RAR transgenic mice | Proceedings of the National Academy of Sciences of the United States of America | 1997 | 345 |
| 15 | Deregulation of MUM1/IRF4 by chromosomal translocation in multiple myeloma | Nature Genetics | 1997 | 322 |
| 16 | Somatic Mutations in Paroxysmal Nocturnal Hemoglobinuria: A Blessing in Disguise? | Cell | 1997 | 295 |
| 17 | Frequency of recurrent BRCA1 and BRCA2 mutations in Ashkenazi Jewish breast cancer families | Nature Medicine | 1996 | 294 |
| 18 | BRCA-associated breast cancer in young women. | Journal of Clinical Oncology | 1998 | 288 |
| 19 | Recurrent BRCA2 6174delT mutations in Ashkenazi Jewish women affected by breast cancer | Nature Genetics | 1996 | 282 |
| 20 | Antigen-dependent CD28 Signaling Selectively Enhances Survival and Proliferation in Genetically Modified Activated Human Primary T Lymphocytes | Journal of Experimental Medicine | 1998 | 268 |
| 21 | The t(8;21) fusion protein, AML1–ETO, specifically represses the transcription of the p14ARF tumor suppressor in acute myeloid leukemia | Nature Medicine | 2002 | 258 |
| 22 | Regulation and Localization of the Bloom Syndrome Protein in Response to DNA Damage | Journal of Cell Biology | 2001 | 257 |
| 23 | DNA HELICASES, GENOMICINSTABILITY,ANDHUMANGENETICDISEASE | Annual Review of Genomics and Human Genetics | 2000 | 232 |
| 24 | Binding and Melting of D-Loops by the Bloom Syndrome Helicase | Biochemistry | 2000 | 218 |
| 25 | A role for PML and the nuclear body in genomic stability | Oncogene | 1999 | 215 |
| 26 | The cHS4 Insulator Increases the Probability of Retroviral Expression at Random Chromosomal Integration Sites | Journal of Virology | 2000 | 198 |
| 27 | Cancer Patient T Cells Genetically Targeted to Prostate-Specific Membrane Antigen Specifically Lyse Prostate Cancer Cells and Release Cytokines in Response to Prostate-Specific Membrane Antigen | Neoplasia | 1999 | 197 |
| 28 | In vivo telomere dynamics of human hematopoietic stem cells | Proceedings of the National Academy of Sciences of the United States of America | 1997 | 194 |
| 29 | Retinoic acid (RA) and As2O3 treatment in transgenic models of acute promyelocytic leukemia (APL) unravel the distinct nature of the leukemogenic process induced by the PML-RARalpha and PLZF-RARalpha oncoproteins | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 193 |
| 30 | ATIC-ALK: A Novel Variant ALK Gene Fusion in Anaplastic Large Cell Lymphoma Resulting from the Recurrent Cryptic Chromosomal Inversion, inv(2)(p23q35) | American Journal of Pathology | 2000 | 168 |
| 31 | Low incidence of BRCA2 mutations in breast carcinoma and other cancers | Nature Genetics | 1996 | 162 |
| 32 | Haplotype and Phenotype Analysis of Nine Recurrent BRCA2 Mutations in 111 Families: Results of an International Study | American Journal of Human Genetics | 1998 | 150 |
| 33 | Human male germ cell tumor resistance to cisplatin is linked to TP53 gene mutation | Oncogene | 1998 | 148 |
| 34 | Risk of Endometrial Carcinoma Associated with BRCA Mutation | Gynecologic Oncology | 2001 | 147 |
| 35 | Germline BRCA1 185delAG mutations in Jewish women with breast cancer | Lancet, The | 1996 | 145 |
| 36 | Cytogenetic analysis of 363 consecutively ascertained diffuse large B-cell lymphomas | | 1999 | 144 |
| 37 | Expression of GPC3, an X-linked recessive overgrowth gene, is silenced in malignant mesothelioma | Oncogene | 2000 | 142 |
| 38 | Lentivirus-transduced human monocyte-derived dendritic cells efficiently stimulate antigen-specific cytotoxic T lymphocytes | Blood | 2001 | 140 |
| 39 | Role of PML and PML-RARα in Mad-Mediated Transcriptional Repression | Molecular Cell | 2001 | 137 |
| 40 | The DNA Helicase Activity of BLM Is Necessary for the Correction of the Genomic Instability of Bloom Syndrome Cells | Molecular Biology of the Cell | 1999 | 132 |
| 41 | Characterization of Nonrandom Chromosomal Gains and Losses in Multiple Myeloma by Comparative Genomic Hybridization | Blood | 1998 | 129 |
| 42 | Functional Interaction of p53 and BLM DNA Helicase in Apoptosis | Journal of Biological Chemistry | 2001 | 129 |
| 43 | A RA-dependent, tumour-growth suppressive transcription complex is the target of the PML-RARα and T18 oncoproteins | Nature Genetics | 1999 | 127 |
| 44 | Maternally transmitted severe glucose 6-phosphate dehydrogenase deficiency is an embryonic lethal | EMBO Journal | 2002 | 123 |
| 45 | Murine embryonic stem cells without pig-a gene activity are competent for hematopoiesis with the PNH phenotype but not for clonal expansion. | Journal of Clinical Investigation | 1997 | 122 |
| 46 | Differential regulation of human RecQ family helicases in cell transformation and cell cycle | Oncogene | 2000 | 116 |
| 47 | Quantitating familial cancer risk: a resource for clinical oncologists. | Journal of Clinical Oncology | 1994 | 112 |
| 48 | Specificity of TLS-CHOP Rearrangement for Classic Myxoid/Round Cell Liposarcoma | Journal of Molecular Diagnostics | 2000 | 112 |
| 49 | Bone marrow transplants for paroxysmal nocturnal haemoglobinuria | British Journal of Haematology | 1999 | 110 |
| 50 | Functional Coexpression of HSV-1 Thymidine Kinase and Green Fluorescent Protein: Implications for Noninvasive Imaging of Transgene Expression | Neoplasia | 1999 | 109 |
