# | Title | Journal | Year | Citations |
---|
1 | Microenvironmental regulation of tumor progression and metastasis | Nature Medicine | 2013 | 5,730 |
2 | The Emerging Hallmarks of Cancer Metabolism | Cell Metabolism | 2016 | 3,943 |
3 | Cancer Metastasis: Building a Framework | Cell | 2006 | 3,702 |
4 | TGFβ in Cancer | Cell | 2008 | 3,312 |
5 | Microenvironmental regulation of metastasis | Nature Reviews Cancer | 2009 | 3,157 |
6 | Somatic mutations affect key pathways in lung adenocarcinoma | Nature | 2008 | 2,694 |
7 | TGFβ signalling in context | Nature Reviews Molecular Cell Biology | 2012 | 2,619 |
8 | Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate | Cancer Cell | 2012 | 2,617 |
9 | Genes that mediate breast cancer metastasis to lung | Nature | 2005 | 2,581 |
10 | Metastasis: from dissemination to organ-specific colonization | Nature Reviews Cancer | 2009 | 2,287 |
11 | Smad transcription factors | Genes and Development | 2005 | 2,063 |
12 | Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis | Nature | 2005 | 1,768 |
13 | Endogenous human microRNAs that suppress breast cancer metastasis | Nature | 2008 | 1,743 |
14 | T cell exclusion, immune privilege, and the tumor microenvironment | Science | 2015 | 1,735 |
15 | IDH mutation impairs histone demethylation and results in a block to cell differentiation | Nature | 2012 | 1,693 |
16 | Genes that mediate breast cancer metastasis to the brain | Nature | 2009 | 1,587 |
17 | Metastatic colonization by circulating tumour cells | Nature | 2016 | 1,498 |
18 | Cytostatic and apoptotic actions of TGF-β in homeostasis and cancer | Nature Reviews Cancer | 2003 | 1,486 |
19 | Epithelial-Mesenchymal Transitions | Cell | 2004 | 1,369 |
20 | Transforming Growth Factor-β Signaling in Immunity and Cancer | Immunity | 2019 | 1,360 |
21 | Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells | Nature | 2013 | 1,316 |
22 | Guidelines and definitions for research on epithelial–mesenchymal transition | Nature Reviews Molecular Cell Biology | 2020 | 1,195 |
23 | Tumor Self-Seeding by Circulating Cancer Cells | Cell | 2009 | 1,182 |
24 | Phosphorylation and Functional Inactivation of TSC2 by Erk | Cell | 2005 | 1,132 |
25 | G1 cell-cycle control and cancer | Nature | 2004 | 1,082 |
26 | TGF-β directly targets cytotoxic T cell functions during tumor evasion of immune surveillance | Cancer Cell | 2005 | 1,057 |
27 | Characterizing the cancer genome in lung adenocarcinoma | Nature | 2007 | 1,020 |
28 | Chromosomal instability drives metastasis through a cytosolic DNA response | Nature | 2018 | 1,002 |
29 | The microcosmos of cancer | Nature | 2012 | 993 |
30 | A CXCL1 Paracrine Network Links Cancer Chemoresistance and Metastasis | Cell | 2012 | 913 |
31 | Integration of Smad and Forkhead Pathways in the Control of Neuroepithelial and Glioblastoma Cell Proliferation | Cell | 2004 | 903 |
32 | Dependency of Colorectal Cancer on a TGF-β-Driven Program in Stromal Cells for Metastasis Initiation | Cancer Cell | 2012 | 881 |
33 | Essential Role for Nuclear PTEN in Maintaining Chromosomal Integrity | Cell | 2007 | 879 |
34 | TGFβ Primes Breast Tumors for Lung Metastasis Seeding through Angiopoietin-like 4 | Cell | 2008 | 852 |
35 | Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 851 |
36 | Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells | Nature | 2015 | 772 |
37 | SOX2 promotes lineage plasticity and antiandrogen resistance in TP53 - and RB1 -deficient prostate cancer | Science | 2017 | 759 |
38 | Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs | Nature Medicine | 2011 | 740 |
39 | Roles of TGFβ in metastasis | Cell Research | 2009 | 739 |
40 | Genetic determinants of cancer metastasis | Nature Reviews Genetics | 2007 | 716 |
41 | Senescence-associated reprogramming promotes cancer stemness | Nature | 2018 | 714 |
42 | Carcinoma–astrocyte gap junctions promote brain metastasis by cGAMP transfer | Nature | 2016 | 677 |
43 | Human Pancreatic Cancer Tumors Are Nutrient Poor and Tumor Cells Actively Scavenge Extracellular Protein | Cancer Research | 2015 | 673 |
44 | Serpins Promote Cancer Cell Survival and Vascular Co-Option in Brain Metastasis | Cell | 2014 | 672 |
45 | Germline mutations in BAP1 predispose to melanocytic tumors | Nature Genetics | 2011 | 662 |
46 | The logic of TGFβ signaling | FEBS Letters | 2006 | 657 |
47 | Ubiquitination Regulates PTEN Nuclear Import and Tumor Suppression | Cell | 2007 | 652 |
48 | Mediators of vascular remodelling co-opted for sequential steps in lung metastasis | Nature | 2007 | 629 |
49 | Nuclear CDKs Drive Smad Transcriptional Activation and Turnover in BMP and TGF-β Pathways | Cell | 2009 | 627 |
50 | Latent Bone Metastasis in Breast Cancer Tied to Src-Dependent Survival Signals | Cancer Cell | 2009 | 609 |