| # | Title | Journal | Year | Citations |
|---|
| 1 | Operating characteristics of a rank correlation test for publication bias | Biometrics | 1994 | 5,751 |
| 2 | Assessing the Performance of Prediction Models | Epidemiology | 2010 | 3,387 |
| 3 | Decision Curve Analysis: A Novel Method for Evaluating Prediction Models | Medical Decision Making | 2006 | 3,292 |
| 4 | Improving the quality of reporting of randomized controlled trials. The CONSORT statement | JAMA - Journal of the American Medical Association | 1996 | 2,883 |
| 5 | Tumor mutational load predicts survival after immunotherapy across multiple cancer types | Nature Genetics | 2019 | 2,702 |
| 6 | Colonoscopic Polypectomy and Long-Term Prevention of Colorectal-Cancer Deaths | New England Journal of Medicine | 2012 | 2,553 |
| 7 | Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients | Nature Medicine | 2017 | 2,473 |
| 8 | How To Build and Interpret a Nomogram for Cancer Prognosis | Journal of Clinical Oncology | 2008 | 2,273 |
| 9 | Nomograms in oncology: more than meets the eye | Lancet Oncology, The | 2015 | 2,187 |
| 10 | Efficacy and Toxicity Management of 19-28z CAR T Cell Therapy in B Cell Acute Lymphoblastic Leukemia | Science Translational Medicine | 2014 | 2,069 |
| 11 | Circular binary segmentation for the analysis of array-based DNA copy number data | Biostatistics | 2004 | 1,903 |
| 12 | Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer | Cell | 2018 | 1,718 |
| 13 | Annual report to the nation on the status of cancer, 1975‐2006, featuring colorectal cancer trends and impact of interventions (risk factors, screening, and treatment) to reduce future rates | Cancer | 2010 | 1,691 |
| 14 | Chronic kidney disease after nephrectomy in patients with renal cortical tumours: a retrospective cohort study | Lancet Oncology, The | 2006 | 1,456 |
| 15 | Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection | Nature | 2017 | 1,314 |
| 16 | The Memorial Symptom Assessment Scale: an instrument for the evaluation of symptom prevalence, characteristics and distress | European Journal of Cancer | 1994 | 1,301 |
| 17 | T-cell invigoration to tumour burden ratio associated with anti-PD-1 response | Nature | 2017 | 1,280 |
| 18 | Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias | Blood | 2011 | 1,135 |
| 19 | Extensions to decision curve analysis, a novel method for evaluating diagnostic tests, prediction models and molecular markers | BMC Medical Informatics and Decision Making | 2008 | 966 |
| 20 | Racial Differences in the Treatment of Early-Stage Lung Cancer | New England Journal of Medicine | 1999 | 944 |
| 21 | A CXCL1 Paracrine Network Links Cancer Chemoresistance and Metastasis | Cell | 2012 | 913 |
| 22 | Dose escalation with three-dimensional conformal radiation therapy affects the outcome in prostate cancer | International Journal of Radiation Oncology Biology Physics | 1998 | 876 |
| 23 | Primary Care Physicians Who Treat Blacks and Whites | New England Journal of Medicine | 2004 | 865 |
| 24 | Genomic correlates of clinical outcome in advanced prostate cancer | Proceedings of the National Academy of Sciences of the United States of America | 2019 | 839 |
| 25 | Acupuncture for Chronic Pain | Archives of Internal Medicine | 2012 | 835 |
| 26 | FACETS: allele-specific copy number and clonal heterogeneity analysis tool for high-throughput DNA sequencing | Nucleic Acids Research | 2016 | 809 |
| 27 | A faster circular binary segmentation algorithm for the analysis of array CGH data | Bioinformatics | 2007 | 805 |
| 28 | Variations in Morbidity after Radical Prostatectomy | New England Journal of Medicine | 2002 | 800 |
| 29 | Tumor immune microenvironment characterization in clear cell renal cell carcinoma identifies prognostic and immunotherapeutically relevant messenger RNA signatures | Genome Biology | 2016 | 746 |
| 30 | Eleven grand challenges in single-cell data science | Genome Biology | 2020 | 742 |
| 31 | High-dose intensity modulated radiation therapy for prostate cancer: early toxicity and biochemical outcome in 772 patients | International Journal of Radiation Oncology Biology Physics | 2002 | 727 |
| 32 | Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis | Nature Genetics | 2012 | 692 |
| 33 | Increasing value and reducing waste: addressing inaccessible research | Lancet, The | 2014 | 692 |
| 34 | Postoperative Nomogram for Disease Recurrence After Radical Prostatectomy for Prostate Cancer | Journal of Clinical Oncology | 1999 | 686 |
| 35 | Integrative clustering of multiple genomic data types using a joint latent variable model with application to breast and lung cancer subtype analysis | Bioinformatics | 2009 | 671 |
| 36 | Long-Term Survival in Metastatic Transitional-Cell Carcinoma and Prognostic Factors Predicting Outcome of Therapy | Journal of Clinical Oncology | 1999 | 658 |
| 37 | The Influence of Hospital Volume on Survival after Resection for Lung Cancer | New England Journal of Medicine | 2001 | 656 |
| 38 | Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity | Nature Biotechnology | 2016 | 634 |
| 39 | The Genomic Landscape of Endocrine-Resistant Advanced Breast Cancers | Cancer Cell | 2018 | 633 |
| 40 | A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder | Molecular Psychiatry | 2008 | 619 |
| 41 | A note on competing risks in survival data analysis | British Journal of Cancer | 2004 | 598 |
| 42 | Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer | Nature Genetics | 2009 | 597 |
| 43 | Clinical and Biological Correlates of Neurotoxicity Associated with CAR T-cell Therapy in Patients with B-cell Acute Lymphoblastic Leukemia | Cancer Discovery | 2018 | 594 |
| 44 | Reporting and Interpreting Decision Curve Analysis: A Guide for Investigators | European Urology | 2018 | 590 |
| 45 | Validity and Reliability of the US National Cancer Institute’s Patient-Reported Outcomes Version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE) | JAMA Oncology | 2015 | 581 |
| 46 | Therapy-Related Clonal Hematopoiesis in Patients with Non-hematologic Cancers Is Common and Associated with Adverse Clinical Outcomes | Cell Stem Cell | 2017 | 578 |
| 47 | Net benefit approaches to the evaluation of prediction models, molecular markers, and diagnostic tests | BMJ, The | 2016 | 577 |
| 48 | Substantial interindividual and limited intraindividual genomic diversity among tumors from men with metastatic prostate cancer | Nature Medicine | 2016 | 572 |
| 49 | Targeted delivery of a PD-1-blocking scFv by CAR-T cells enhances anti-tumor efficacy in vivo | Nature Biotechnology | 2018 | 564 |
| 50 | Circulating tumour cells as prognostic markers in progressive, castration-resistant prostate cancer: a reanalysis of IMMC38 trial data | Lancet Oncology, The | 2009 | 558 |
