| # | Title | Journal | Year | Citations |
|---|
| 1 | Preparation, characterization, and potential application of chitosan, chitosan derivatives, and chitosan metal nanoparticles in pharmaceutical drug delivery | Drug Design, Development and Therapy | 2016 | 471 |
| 2 | Stimuli-Responsive Nano-Architecture Drug-Delivery Systems to Solid Tumor Micromilieu: Past, Present, and Future Perspectives | ACS Nano | 2018 | 320 |
| 3 | Glutathione-Responsive Prodrug Nanoparticles for Effective Drug Delivery and Cancer Therapy | ACS Nano | 2019 | 204 |
| 4 | Exploring recent developments to improve antioxidant, anti-inflammatory and antimicrobial efficacy of curcumin: A review of new trends and future perspectives | Materials Science and Engineering C | 2017 | 194 |
| 5 | Antibiotic penetration into bone and joints: An updated review | International Journal of Infectious Diseases | 2019 | 192 |
| 6 | Minor to Moderate Side Effects of Pfizer-BioNTech COVID-19 Vaccine Among Saudi Residents: A Retrospective Cross-Sectional Study | International Journal of General Medicine | 2021 | 168 |
| 7 | Exosomes as nanocarriers for immunotherapy of cancer and inflammatory diseases | Clinical Immunology | 2015 | 148 |
| 8 | Phage Display Derived Monoclonal Antibodies: From Bench to Bedside | Frontiers in Immunology | 2020 | 146 |
| 9 | Anti-angiogenic agents for the treatment of solid tumors: Potential pathways, therapy and current strategies – A review | Journal of Advanced Research | 2017 | 142 |
| 10 | Compritol 888 ATO: a multifunctional lipid excipient in drug delivery systems and nanopharmaceuticals | Expert Opinion on Drug Delivery | 2014 | 141 |
| 11 | Pancreatic Cancer Cell Exosome-Mediated Macrophage Reprogramming and the Role of MicroRNAs 155 and 125b2 Transfection using Nanoparticle Delivery Systems | Scientific Reports | 2016 | 136 |
| 12 | Fingolimod interrupts the cross talk between estrogen metabolism and sphingolipid metabolism within prostate cancer cells | Toxicology Letters | 2018 | 127 |
| 13 | Molecular Docking and Dynamics Simulation Revealed the Potential Inhibitory Activity of ACEIs Against SARS-CoV-2 Targeting the hACE2 Receptor | Frontiers in Chemistry | 2021 | 122 |
| 14 | Dispensing medications without prescription at Saudi community pharmacy: Extent and perception | Saudi Pharmaceutical Journal | 2013 | 110 |
| 15 | Immune checkpoint inhibitors: a promising anticancer therapy | Drug Discovery Today | 2020 | 110 |
| 16 | Development of Pharmaceutical Nanomedicines: From the Bench to the Market | Pharmaceutics | 2022 | 109 |
| 17 | Fabrication, Optimization, and Evaluation of Rotigotine-Loaded Chitosan Nanoparticles for Nose-To-Brain Delivery | Pharmaceutics | 2019 | 93 |
| 18 | Cranberry (Vaccinium macrocarpon) protects against doxorubicin-induced cardiotoxicity in rats | Food and Chemical Toxicology | 2010 | 91 |
| 19 | Nose to brain delivery of rotigotine loaded chitosan nanoparticles in human SH-SY5Y neuroblastoma cells and animal model of Parkinson's disease | International Journal of Pharmaceutics | 2020 | 91 |
| 20 | Apratoxin H and Apratoxin A Sulfoxide from the Red Sea Cyanobacterium Moorea producens | Journal of Natural Products | 2013 | 88 |
| 21 | The hidden mechanism beyond ginger ( Zingiber officinale Rosc.) potent in vivo and in vitro anti-inflammatory activity | Journal of Ethnopharmacology | 2018 | 88 |
| 22 | Icariin modulates carrageenan-induced acute inflammation through HO-1/Nrf2 and NF-kB signaling pathways | Biomedicine and Pharmacotherapy | 2019 | 85 |
| 23 | Dibutyl phthalate induces oxidative stress and impairs spermatogenesis in adult rats | Toxicology and Industrial Health | 2016 | 84 |
| 24 | Effect of nonylphenol on male reproduction: Analysis of rat epididymal biochemical markers and antioxidant defense enzymes | Toxicology and Applied Pharmacology | 2012 | 81 |
| 25 | Methanolic extract of Marrubium vulgare ameliorates hyperglycemia and dyslipidemia in streptozotocin-induced diabetic rats | International Journal of Diabetes Mellitus | 2015 | 78 |
| 26 | Extracellular vesicles from triple-negative breast cancer cells promote proliferation and drug resistance in non-tumorigenic breast cells | Breast Cancer Research and Treatment | 2018 | 78 |
| 27 | Chemical composition, insecticidal and insect repellent activity of Schinus molle L. leaf and fruit essential oils against Trogoderma granarium and Tribolium castaneum | Natural Product Research | 2010 | 77 |
| 28 | Miconazole-loaded solid lipid nanoparticles: formulation and evaluation of a novel formula with high bioavailability and antifungal activity | International Journal of Nanomedicine | 2016 | 76 |
| 29 | The Multifaceted Role of Curcumin in Advanced Nanocurcumin Form in the Treatment and Management of Chronic Disorders | Molecules | 2021 | 75 |
| 30 | Chemical Adulterants in Herbal Medicinal Products: A Review | Planta Medica | 2016 | 74 |
| 31 | Rising horizon in circumventing multidrug resistance in chemotherapy with nanotechnology | Materials Science and Engineering C | 2019 | 71 |
| 32 | Formulation Design, Statistical Optimization, and In Vitro Evaluation of a Naringenin Nanoemulsion to Enhance Apoptotic Activity in A549 Lung Cancer Cells | Pharmaceuticals | 2020 | 70 |
| 33 | Synthesis andin vitroanticancer activity of certain novel 1-(2-methyl-6-arylpyridin-3-yl)-3-phenylureas as apoptosis-inducing agents | Journal of Enzyme Inhibition and Medicinal Chemistry | 2019 | 69 |
| 34 | Phytosomes as an Emerging Nanotechnology Platform for the Topical Delivery of Bioactive Phytochemicals | Pharmaceutics | 2021 | 69 |
| 35 | Transdermal glimepiride delivery system based on optimized ethosomal nano-vesicles: Preparation, characterization, in vitro , ex vivo and clinical evaluation | International Journal of Pharmaceutics | 2016 | 68 |
| 36 | New Constituents from the Rhizomes of Egyptian Iris germanica L. | Molecules | 2012 | 67 |
| 37 | In vitro cytotoxic screening of selected Saudi medicinal plants | Journal of Natural Medicines | 2012 | 67 |
| 38 | Optimized extraction method for LC–MS determination of bisphenol A, melamine and di(2-ethylhexyl) phthalate in selected soft drinks, syringes, and milk powder | Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences | 2013 | 66 |
| 39 | Acylated pregnane glycosides from Caralluma tuberculata and their antiparasitic activity | Phytochemistry | 2008 | 65 |
| 40 | Calendulaglycoside A showing potential activity against SARS-CoV-2 main protease: Molecular docking, molecular dynamics, and SAR studies | Journal of Traditional and Complementary Medicine | 2022 | 64 |
| 41 | Polysubstituted pyrazoles, part 6. Synthesis of some 1-(4-chlorophenyl)-4-hydroxy-1H-pyrazol-3-carbonyl derivatives linked to nitrogenous heterocyclic ring systems as potential antitumor agents | Bioorganic and Medicinal Chemistry | 2010 | 63 |
| 42 | Theonellamide G, a Potent Antifungal and Cytotoxic Bicyclic Glycopeptide from the Red Sea Marine Sponge Theonella swinhoei | Marine Drugs | 2014 | 63 |
| 43 | Clinical efficacy of new aloe vera‐ and myrrh‐based oral mucoadhesive gels in the management of minor recurrent aphthous stomatitis: a randomized, double‐blind, vehicle‐controlled study | Journal of Oral Pathology and Medicine | 2014 | 63 |
| 44 | Phenolic compounds from Syzygium jambos (Myrtaceae) exhibit distinct antioxidant and hepatoprotective activities in vivo | Journal of Functional Foods | 2018 | 63 |
| 45 | Fusaripeptide A: new antifungal and anti-malarial cyclodepsipeptide from the endophytic fungusFusarium sp. | Journal of Asian Natural Products Research | 2018 | 63 |
| 46 | Naturally occurring thiophenes: isolation, purification, structural elucidation, and evaluation of bioactivities | Phytochemistry Reviews | 2016 | 62 |
| 47 | RGD engineered dendrimer nanotherapeutic as an emerging targeted approach in cancer therapy | Journal of Controlled Release | 2021 | 62 |
| 48 | Caffeic acid phenethyl ester protects against tamoxifen-induced hepatotoxicity in rats | Food and Chemical Toxicology | 2009 | 59 |
| 49 | In Vitro activities of plant extracts from Saudi Arabia against malaria, leishmaniasis, sleeping sickness and Chagas disease | Phytotherapy Research | 2010 | 57 |
| 50 | Chemical Diversity and Bioactivities of Monoterpene Indole Alkaloids (MIAs) from Six Apocynaceae Genera | Molecules | 2021 | 57 |
