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Top Articles

#TitleJournalYearCitations
1Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1Autophagy20211,430
2Prognostic and Predictive Molecular Biomarkers for Colorectal Cancer: Updates and ChallengesCancers2020141
3Microbiome in Colorectal Cancer: How to Get from Meta-omics to Mechanism?Trends in Microbiology2020135
4The gut microbial metabolite formate exacerbates colorectal cancer progressionNature Metabolism202297
5NRAS mutant melanoma: Towards better therapiesCancer Treatment Reviews202156
6Stromal fibroblasts shape the myeloid phenotype in normal colon and colorectal cancer and induce CD163 and CCL2 expression in macrophagesCancer Letters202140
7Highly Multiplexed Targeted Proteomics Acquisition on a TIMS-QTOFAnalytical Chemistry202138
8Postprandial Hyperglycemia Stimulates Neuroglial Plasticity in Hypothalamic POMC Neurons after a Balanced MealCell Reports202033
9Hypoxia-Induced Adaptations of miRNomes and Proteomes in Melanoma Cells and Their Secreted Extracellular VesiclesCancers202032
10Fusobacterium nucleatum Extracellular Vesicles Modulate Gut Epithelial Cell Innate Immunity via FomA and TLR2Frontiers in Immunology202029
11A Census and Categorization Method of Epitranscriptomic MarksInternational Journal of Molecular Sciences202029
12Mechanisms of Ras Membrane Organization and Signaling: Ras Rocks AgainBiomolecules202028
13Mapping the Metabolic Networks of Tumor Cells and Cancer-Associated FibroblastsCells202123
14Pharmacophore Model for SARS-CoV-2 3CLpro Small-Molecule Inhibitors and in Vitro Experimental Validation of Computationally Screened InhibitorsJournal of Chemical Information and Modeling202122
15Integrative approaches for analysis of mRNA and microRNA high-throughput dataComputational and Structural Biotechnology Journal202120
16Mitochondria preserve an autarkic one-carbon cycle to confer growth-independent cancer cell migration and metastasisNature Communications202220
17Phagocytosis‐related NADPH oxidase 2 subunit gp91phox contributes to neurodegeneration after repeated systemic challenge with lipopolysaccharidesGlia202117
18DCcov: Repositioning of drugs and drug combinations for SARS-CoV-2 infected lung through constraint-based modelingIScience202116
19Evolution of the murine gut resistome following broad-spectrum antibiotic treatmentNature Communications202216
20Alterations of oral microbiota and impact on the gut microbiome in type 1 diabetes mellitus revealed by integrated multi-omic analysesMicrobiome202216
21A Universal Peptide Matrix Interactomics Approach to Disclose Motif-Dependent Protein BindingMolecular and Cellular Proteomics202115
22Neutrophils in Tumorigenesis: Missing Targets for Successful Next Generation Cancer Therapies?International Journal of Molecular Sciences202115
23ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1Frontiers in Oncology202115
24Promotion of cancer cell stemness by RasBiochemical Society Transactions202114
25Cross-Linking Ligation and Sequencing of Hybrids (qCLASH) Reveals an Unpredicted miRNA Targetome in Melanoma CellsCancers202114
26A Covalent Calmodulin Inhibitor as a Tool to Study Cellular Mechanisms of K-Ras-Driven StemnessFrontiers in Cell and Developmental Biology202113
27Stress-induced inflammation evoked by immunogenic cell death is blunted by the IRE1α kinase inhibitor KIRA6 through HSP60 targetingCell Death and Differentiation202212
28Novel Small Molecule Hsp90/Cdc37 Interface Inhibitors Indirectly Target K-Ras-SignalingCancers202111
29Nanopore Single-Molecule Sequencing for Mitochondrial DNA Methylation Analysis: Investigating Parkin-Associated Parkinsonism as a Proof of ConceptFrontiers in Aging Neuroscience202111
30NF-κB and TNF Affect the Astrocytic Differentiation from Neural Stem CellsCells202110
31A dynamic multi-tissue model to study human metabolismNpj Systems Biology and Applications202110
32Potential of phenothiazines to synergistically block calmodulin and reactivate PP2A in cancer cellsPLoS ONE202210
33Formate overflow drives toxic folate trapping in MTHFD1 inhibited cancer cellsNature Metabolism202310
34Eliminating oncogenic RAS: back to the future at the drawing boardBiochemical Society Transactions20239
35NRAS is unique among RAS proteins in requiring ICMT for trafficking to the plasma membraneLife Science Alliance20218
36Challenges, Strategies, and Perspectives for Reference-Independent Longitudinal Multi-Omic Microbiome StudiesFrontiers in Genetics20218
37Importance of the biomass formulation for cancer metabolic modeling and drug predictionIScience20218
38Focal adhesion kinase plays a dual role in TRAIL resistance and metastatic outgrowth of malignant melanomaCell Death and Disease20228
39Investigating children’s chemical exposome – Description and possible determinants of exposure in the region of Luxembourg based on hair analysisEnvironment International20228
40L-plastin Ser5 phosphorylation is modulated by the PI3K/SGK pathway and promotes breast cancer cell invasivenessCell Communication and Signaling20217
41Drug targeting opportunities en route to Ras nanoclustersAdvances in Cancer Research20225
42Pituitary Tumor Transforming Gene 1 Orchestrates Gene Regulatory Variation in Mouse Ventral Midbrain During AgingFrontiers in Genetics20204
43Systematic Transcriptional Profiling of Responses to STAT1- and STAT3-Activating Cytokines in Different Cancer TypesJournal of Molecular Biology20203
44Bruceine D Identified as a Drug Candidate against Breast Cancer by a Novel Drug Selection Pipeline and Cell Viability AssayPharmaceuticals20223
45Project-based learning course on metabolic network modelling in computational systems biologyPLoS Computational Biology20223
46EGFR-induced suppression of HPV E6/E7 is mediated by microRNA-9-5p silencing of BRD4 protein in HPV-positive head and neck squamous cell carcinomaCell Death and Disease20223
47Degree Adjusted Large-Scale Network Analysis Reveals Novel Putative Metabolic Disease GenesBiology20212
48IDARE2—Simultaneous Visualisation of Multiomics Data in CytoscapeMetabolites20212
49Role of S100A8/A9 for Cytokine Secretion, Revealed in Neutrophils Derived from ER-Hoxb8 ProgenitorsInternational Journal of Molecular Sciences20212
50Construction and contextualization approaches for protein-protein interaction networksComputational and Structural Biotechnology Journal20222