# | Title | Journal | Year | Citations |
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1 | A genomic overview of pyridoxal‐phosphate‐dependent enzymes | EMBO Reports | 2003 | 448 |
2 | The B6 database: a tool for the description and classification of vitamin B6-dependent enzymatic activities and of the corresponding protein families | BMC Bioinformatics | 2009 | 240 |
3 | 17A, a novel non-coding RNA, regulates GABA B alternative splicing and signaling in response to inflammatory stimuli and in Alzheimer disease | Neurobiology of Disease | 2011 | 199 |
4 | Transient Receptor Potential Ankyrin 1 Channel Localized to Non-Neuronal Airway Cells Promotes Non-Neurogenic Inflammation | PLoS ONE | 2012 | 194 |
5 | Retinoids Regulate Survival and Antigen Presentation by Immature Dendritic Cells | Journal of Experimental Medicine | 2003 | 143 |
6 | Simple, Intuitive Calculations of Free Energy of Binding for Protein−Ligand Complexes. 1. Models without Explicit Constrained Water | Journal of Medicinal Chemistry | 2002 | 131 |
7 | An intronic ncRNA-dependent regulation of SORL1 expression affecting Aβ formation is upregulated in post-mortem Alzheimer's disease brain samples | DMM Disease Models and Mechanisms | 2013 | 131 |
8 | Plasma Retinol-Binding Protein: Structure and Interactions with Retinol, Retinoids, and Transthyretin | Vitamins and Hormones | 2004 | 130 |
9 | Structures of γ-Aminobutyric Acid (GABA) Aminotransferase, a Pyridoxal 5′-Phosphate, and [2Fe-2S] Cluster-containing Enzyme, Complexed with γ-Ethynyl-GABA and with the Antiepilepsy Drug Vigabatrin | Journal of Biological Chemistry | 2004 | 129 |
10 | Crystal Structure of Peach Pru p 3, the Prototypic Member of the Family of Plant Non-specific Lipid Transfer Protein Pan-allergens | Journal of Molecular Biology | 2006 | 122 |
11 | “Muscle to meat” molecular events and technological transformations: The proteomics insight | Journal of Proteomics | 2012 | 115 |
12 | Simple, Intuitive Calculations of Free Energy of Binding for Protein−Ligand Complexes. 3. The Free Energy Contribution of Structural Water Molecules in HIV-1 Protease Complexes | Journal of Medicinal Chemistry | 2004 | 112 |
13 | Evolution of allosteric models for hemoglobin | IUBMB Life | 2007 | 103 |
14 | Collision events between RNA polymerases in convergent transcription studied by atomic force microscopy | Nucleic Acids Research | 2006 | 102 |
15 | Membrane transporters and protein traffic networks differentially affecting metal tolerance: a genomic phenotyping study in yeast | Genome Biology | 2008 | 97 |
16 | Robust Classification of “Relevant” Water Molecules in Putative Protein Binding Sites | Journal of Medicinal Chemistry | 2008 | 93 |
17 | Free Energy of Ligand Binding to Protein: Evaluation of the Contribution of Water Molecules by Computational Methods | Current Medicinal Chemistry | 2004 | 89 |
18 | Mapping the Energetics of Water–Protein and Water–Ligand Interactions with the “Natural” HINT Forcefield: Predictive Tools for Characterizing the Roles of Water in Biomolecules | Journal of Molecular Biology | 2006 | 85 |
19 | Interaction of serine acetyltransferase withO-acetylserine sulfhydrylase active site: Evidence from fluorescence spectroscopy | Protein Science | 2005 | 83 |
20 | A Mutational Analysis of the 8–17 Deoxyribozyme Core | Journal of Molecular Biology | 2005 | 83 |
21 | Tryptophan synthase: a mine for enzymologists | Cellular and Molecular Life Sciences | 2009 | 83 |
22 | Stable changes in CD4+ T lymphocyte miRNA expression after exposure to HIV-1 | Blood | 2012 | 83 |
23 | Enzyme catalysis: removing chemically ‘essential’ residues by site-directed mutagenesis | Trends in Biochemical Sciences | 2001 | 82 |
24 | Ligand Binding and Structural Analysis of a Human Putative Cellular Retinol-binding Protein | Journal of Biological Chemistry | 2002 | 80 |
25 | The N-terminal region of the human papillomavirus L2 protein contains overlapping binding sites for neutralizing, cross-neutralizing and non-neutralizing antibodies | Virology | 2011 | 80 |
26 | Simple, Intuitive Calculations of Free Energy of Binding for Protein−Ligand Complexes. 2. Computational Titration and pH Effects in Molecular Models of Neuraminidase−Inhibitor Complexes | Journal of Medicinal Chemistry | 2003 | 77 |
27 | Potent anti-HPV immune responses induced by tandem repeats of the HPV16 L2 (20–38) peptide displayed on bacterial thioredoxin | Vaccine | 2009 | 76 |
28 | DNA Catalysis: Potential, Limitations, Open Questions | ChemBioChem | 2005 | 75 |
29 | Design of O-Acetylserine Sulfhydrylase Inhibitors by Mimicking Nature | Journal of Medicinal Chemistry | 2010 | 75 |
30 | High and low oxygen affinity conformations of T state hemoglobin | Protein Science | 2008 | 74 |
31 | Identification of Xenoestrogens in Food Additives by an Integrated in Silico and in Vitro Approach | Chemical Research in Toxicology | 2009 | 74 |
32 | An Alu‐like RNA promotes cell differentiation and reduces malignancy of human neuroblastoma cells | FASEB Journal | 2010 | 71 |
33 | Prospects for antiviral ribozymes and deoxyribozymes | Reviews in Medical Virology | 2004 | 70 |
34 | Kinetic and thermodynamic characterization of the RNA-cleaving 8-17 deoxyribozyme | Nucleic Acids Research | 2004 | 66 |
35 | Conformation-sensitive Antibodies against Alzheimer Amyloid-β by Immunization with a Thioredoxin-constrained B-cell Epitope Peptide | Journal of Biological Chemistry | 2007 | 66 |
36 | Visualizing RNA Extrusion and DNA Wrapping in Transcription Elongation Complexes of Bacterial and Eukaryotic RNA Polymerases | Journal of Molecular Biology | 2003 | 62 |
37 | Logical Identification of an Allantoinase Analog (puuE) Recruited from Polysaccharide Deacetylases | Journal of Biological Chemistry | 2008 | 62 |
38 | Dynamics of green fluorescent protein mutant2 in solution, on spin-coated glasses, and encapsulated in wet silica gels | Protein Science | 2002 | 61 |
39 | Exploring and exploiting allostery: Models, evolution, and drug targeting | Biochimica Et Biophysica Acta - Proteins and Proteomics | 2011 | 60 |
40 | Rapid Fluorimetric Method to Detect Total Plasma Malondialdehyde with Mild Derivatization Conditions | Clinical Chemistry | 2003 | 59 |
41 | The consequences of scoring docked ligand conformations using free energy correlations | European Journal of Medicinal Chemistry | 2007 | 58 |
42 | Energetics of the protein-DNA-water interaction | BMC Structural Biology | 2007 | 57 |
43 | Bound Water at Protein-Protein Interfaces: Partners, Roles and Hydrophobic Bubbles as a Conserved Motif | PLoS ONE | 2011 | 57 |
44 | The γ-Secretase Modulator CHF5074 Restores Memory and Hippocampal Synaptic Plasticity in Plaque-Free Tg2576 Mice | Journal of Alzheimer's Disease | 2011 | 53 |
45 | A Spring-loaded Release Mechanism Regulates Domain Movement and Catalysis in Phosphoglycerate Kinase | Journal of Biological Chemistry | 2011 | 53 |
46 | Structure of Zebra fish HIUase: Insights into Evolution of an Enzyme to a Hormone Transporter | Journal of Molecular Biology | 2006 | 52 |
47 | Exploring the pyridoxal 5′-phosphate-dependent enzymes | Chemical Record | 2006 | 52 |
48 | Doxycycline counteracts neuroinflammation restoring memory in Alzheimer's disease mouse models | Neurobiology of Aging | 2018 | 52 |
49 | Microspectrophotometry for structural enzymology | Current Opinion in Structural Biology | 2004 | 51 |
50 | Light-Driven Release from Polymeric Microcapsules Functionalized with Bacteriorhodopsin | Journal of the American Chemical Society | 2009 | 49 |