Department of Clinical Biochemistry

140(top 1%)

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#	Title	Journal	Year	Citations
1	Reduced bone density in patients with inflammatory bowel disease.	Gut	1997	316
2	A New Mechanism for Bile Acid Diarrhea: Defective Feedback Inhibition of Bile Acid Biosynthesis	Clinical Gastroenterology and Hepatology	2009	280
3	Comparison of enteral feeding and total parenteral nutrition after liver transplantation	Lancet, The	1994	198
4	Heavy Metal Poisoning and its Laboratory Investigation	Annals of Clinical Biochemistry	1999	168
5	Efavirenz is associated with severe vitamin D deficiency and increased alkaline phosphatase	Aids	2010	168
6	A novel monoclonal antibody to characterize pathogenic polymers in liver disease associated with α₁-antitrypsin deficiency	Hepatology	2010	138
7	The effect of growth hormone replacement on cortisol metabolism and glucocorticoid sensitivity in hypopituitary adults	Clinical Endocrinology	1994	121
8	Randomised clinical trial: a liquid multi-strain probiotic vs. placebo in the irritable bowel syndrome - a 12 week double-blind study	Alimentary Pharmacology and Therapeutics	2014	121
9	ACP Best Practice No 165: Front line tests for the investigation of suspected porphyria	Journal of Clinical Pathology	2001	117
10	The effect of growth hormone replacement therapy on cortisol-cortisone interconversion in hypopituitary adults: evidence for growth hormone modulation of extrarenal 11beta-hydroxysteroid dehydrogenase activity	Clinical Endocrinology	1998	115
11	Plasma Citrulline Concentration	American Journal of Gastroenterology	2007	113
12	The Association Between Depressive Symptoms and Systemic Inflammation in People With Type 2 Diabetes: Findings From the South London Diabetes Study	Diabetes Care	2014	95
13	Dissociation of Bone Turnover in Anorexia Nervosa	Annals of Clinical Biochemistry	1998	89
14	Aerobic or Resistance Training and Pulse Wave Velocity in Kidney Transplant Recipients: A 12-Week Pilot Randomized Controlled Trial (the Exercise in Renal Transplant [ExeRT] Trial)	American Journal of Kidney Diseases	2015	80
15	The importance of alcohol-induced muscle disease	Journal of Muscle Research and Cell Motility	2003	79
16	Diurnal patterns of salivary cortisol and cortisone output in chronic fatigue syndrome	Journal of Affective Disorders	2005	79
17	Metabolic bone disease is present at diagnosis in patients with inflammatory bowel disease	Alimentary Pharmacology and Therapeutics	2002	76
18	Biochemical diagnosis of Antley-Bixler syndrome by steroid analysis	American Journal of Medical Genetics Part A	2004	74
19	Fecal M2-pyruvate kinase (M2-PK): A novel marker of intestinal inflammation	Inflammatory Bowel Diseases	2007	74
20	Turbulent flow chromatography in bioanalysis: a review	Biomedical Chromatography	2012	68
21	A Randomised Controlled Trial of Neuronavigated Repetitive Transcranial Magnetic Stimulation (rTMS) in Anorexia Nervosa	PLoS ONE	2016	66
22	Audit of the Use of Regular Haem Arginate Infusions in Patients with Acute Porphyria to Prevent Recurrent Symptoms	JIMD Reports	2015	65
23	Sexual dimorphism in 11 β hydroxysteroid dehydrogenase activity and its relation to fat distribution and insulin sensitivity; a study in hypopituitary subjects	Clinical Endocrinology	1998	61
24	Experimental non-steroidal anti-inflammatory drug-induced enteropathy in the rat: similarities to inflammatory bowel disease and effect of thromboxane synthetase inhibitors.	Gut	1990	60
25	Prevalence of vitamin D inadequacy in osteoporotic hip fracture patients in London	Current Medical Research and Opinion	2005	60
26	The relationship between the effects of metyrapone treatment on depressed mood and urinary steroid profiles	Psychoneuroendocrinology	1996	59
27	Parathyroid hormone-related peptide: Expression in fetal and neonatal development	Journal of Pathology	1992	58
28	A comparison of the effects of alfacalcidol treatment and vitamin D2 supplementation on calcium absorption in elderly women with vertebral fractures	Osteoporosis International	1996	57
29	Commercial insulin immunoassays fail to detect commonly prescribed insulin analogues	Clinical Biochemistry	2015	55
30	The interpretation of hair analysis for drugs and drug metabolites	Clinical Toxicology	2018	55
31	Extra-adrenal effects of metyrapone include inhibition of the 11-oxoreductase activity of 11β-hydroxysteroid dehydrogenase: a model for 11-HSD I deficiency	Clinical Endocrinology	1995	51
32	Comparison of cardiac troponin T and I and CK-MB for the detection of minor myocardial damage during interventional cardiac procedures	Annals of Clinical Biochemistry	2000	50
33	The effects of growth hormone deficiency and replacement on glucocorticoid exposure in hypopituitary patients on cortisone acetate and hydrocortisone replacement	Clinical Endocrinology	2003	50
34	Effect of fat distribution on endothelial-dependent and endothelial-independent vasodilatation in healthy humans	Diabetes, Obesity and Metabolism	2006	50
35	Urinary excretion of porphyrins, porphobilinogen and δ-aminolaevulinic acid following an attack of acute intermittent porphyria	Journal of Clinical Pathology	2014	50
36	Ras-MEK-ERK signaling cascade regulates androgen receptor element-inducible gene transcription and DNA synthesis in prostate cancer cells	International Journal of Cancer	2007	49
37	High density lipoprotein in patients with liver failure; relation to sepsis, adrenal function and outcome of illness	Liver International	2012	46
38	An overview of the prevalence of 25‐hydroxy-vitamin D inadequacy amongst elderly patients with or without fragility fracture in the United Kingdom	Current Medical Research and Opinion	2006	45
39	Plasma Homocysteine and Cognitive Impairment in an Older British African‐Caribbean Population	Journal of the American Geriatrics Society	2002	44
40	High-dose fish oil and antioxidants in Crohn's disease and the response of bone turnover: a randomised controlled trial	British Journal of Nutrition	2005	44
41	Hepatic hemangioendothelioma associated with production of humoral thyrotropin-like factor	Journal of Pediatrics	2001	43
42	Use of a Clinically Approved Iron Oxide MRI Contrast Agent to Label Human Hepatocytes	Cell Transplantation	2011	42
43	Analysis of adipokine concentrations in paediatric non‐alcoholic fatty liver disease	Pediatric Obesity	2012	42
44	Control of cellular iron homeostasis by iron-responsive elements in vivo	FEBS Journal	1994	41
45	Effects of folic acid supplementation on inflammatory and thrombogenic markers in chronic smokers. A randomised controlled trial	Thrombosis Research	2003	41
46	Substance use by liver transplant candidates: An anonymous urinalysis study	Liver Transplantation	2011	40
47	Alterations in Nutritional Status and Disease Activity during Treatment of Crohn's Disease with Elemental Diet	Scandinavian Journal of Gastroenterology	1995	39
48	Identification of Acute Porphyria: Evaluation of a Commercial Screening Test for Urinary Porphobilinogen	Annals of Clinical Biochemistry	1998	39
49	The Neonatal Detection of Cystic Fibrosis by Measurement of Immunoreactive Trypsin in Blood	Annals of Clinical Biochemistry	1992	38
50	Primary cultures of prostate cells and their ability to activate carcinogens	Prostate Cancer and Prostatic Diseases	2002	38

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