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Top Articles

#TitleJournalYearCitations
1Guidelines for the use of flow cytometry and cell sorting in immunological studies*European Journal of Immunology2017505
2M2 Macrophage-Derived Exosomes Promote Cell Migration and Invasion in Colon CancerCancer Research2019446
3Clinical characteristics and risk factors associated with COVID-19 disease severity in patients with cancer in Wuhan, China: a multicentre, retrospective, cohort studyLancet Oncology, The2020421
4Delivery of chemotherapeutic drugs in tumour cell-derived microparticlesNature Communications2012387
5miR‐142‐3p restricts cAMP production in CD4+CD25 T cells and CD4+CD25+ TREG cells by targeting AC9 mRNAEMBO Reports2009243
6A comparison study of SARS‐CoV‐2 IgG antibody between male and female COVID‐19 patients: A possible reason underlying different outcome between sexJournal of Medical Virology2020230
7Interleukin-33 Ameliorates Experimental Colitis through Promoting Th2/Foxp3+ Regulatory T-Cell Responses in MiceMolecular Medicine2012162
8Matrix softness regulates plasticity of tumour-repopulating cells via H3K9 demethylation and Sox2 expressionNature Communications2014162
9MicroRNA-21 is involved in osteosarcoma cell invasion and migrationMedical Oncology2011161
10Selenium–GPX4 axis protects follicular helper T cells from ferroptosisNature Immunology2021158
11Transmembrane TNF-α Promotes Suppressive Activities of Myeloid-Derived Suppressor Cells via TNFR2Journal of Immunology2014148
12Mast Cells Mobilize Myeloid-Derived Suppressor Cells and Treg Cells in Tumor Microenvironment via IL-17 Pathway in Murine Hepatocarcinoma ModelPLoS ONE2010145
13CD14: Biology and role in the pathogenesis of diseaseCytokine and Growth Factor Reviews2019141
14Extracellular Hmgb1 Functions as an Innate Immune-Mediator Implicated in Murine Cardiac Allograft Acute RejectionAmerican Journal of Transplantation2007137
15Lactate in the tumour microenvironment: From immune modulation to therapyEBioMedicine2021132
16EZH2 is crucial for both differentiation of regulatory T cells and T effector cell expansionScientific Reports2015129
17Erythropoietin prevents PC12 cells from 1-methyl-4-phenylpyridinium ion-induced apoptosis via the Akt/GSK-3β/caspase-3 mediated signaling pathwayApoptosis: an International Journal on Programmed Cell Death2007118
18Gene Silencing of NALP3 Protects Against Liver Ischemia–Reperfusion Injury in MiceHuman Gene Therapy2011117
19Glycogen metabolism regulates macrophage-mediated acute inflammatory responsesNature Communications2020114
20Interferon-γ induces tumor resistance to anti-PD-1 immunotherapy by promoting YAP phase separationMolecular Cell2021114
21Late-stage tumors induce anemia and immunosuppressive extramedullary erythroid progenitor cellsNature Medicine2018112
22Ketogenesis-generated β-hydroxybutyrate is an epigenetic regulator of CD8+ T-cell memory developmentNature Cell Biology2020104
23Extracellular High-Mobility Group Box 1 Acts as an Innate Immune Mediator to Enhance Autoimmune Progression and Diabetes Onset in NOD MiceDiabetes2008101
24The macrophage-specific V-ATPase subunit ATP6V0D2 restricts inflammasome activation and bacterial infection by facilitating autophagosome-lysosome fusionAutophagy2019101
25Fabrication of Stable and RNase-Resistant RNA Nanoparticles Active in Gearing the Nanomotors for Viral DNA PackagingACS Nano201195
26Neutralization of the extracellular HMGB1 released by ischaemic-damaged renal cells protects against renal ischaemia-reperfusion injuryNephrology Dialysis Transplantation201195
27Interleukin-33 ameliorates ischemic brain injury in experimental stroke through promoting Th2 response and suppressing Th17 responseBrain Research201595
28Immune modulation of liver sinusoidal endothelial cells by melittin nanoparticles suppresses liver metastasisNature Communications201993
29IL-33 accelerates cutaneous wound healing involved in upregulation of alternatively activated macrophagesMolecular Immunology201388
30Tumor cell-derived microparticles polarize M2 tumor-associated macrophages for tumor progressionOncoImmunology201685
31Targeting Transmembrane TNF-α Suppresses Breast Cancer GrowthCancer Research201382
32Curcumin induces apoptosis and protective autophagy in castration-resistant prostate cancer cells through iron chelationDrug Design, Development and Therapy201782
33Polyethylenimine-based micro/nanoparticles as vaccine adjuvantsInternational Journal of Nanomedicine201778
34Resistance to chemotherapy-induced apoptosis via decreased caspase-3 activity and overexpression of antiapoptotic proteins in ovarian cancerJournal of Cancer Research and Clinical Oncology200476
35Blockade of Tumor Necrosis Factor (TNF) Receptor Type 1-Mediated TNF-α Signaling Protected Wistar Rats from Diet-Induced Obesity and Insulin ResistanceEndocrinology200874
36Interleukin-7 Biology and Its Effects on Immune Cells: Mediator of Generation, Differentiation, Survival, and HomeostasisFrontiers in Immunology202173
37Vα24-Invariant NKT Cells from Patients with Allergic Asthma Express CCR9 at High Frequency and Induce Th2 Bias of CD3+T Cells upon CD226 EngagementJournal of Immunology200572
38Acid-Sensing Ion Channels Contribute to the Effect of Acidosis on the Function of Dendritic CellsJournal of Immunology201170
39Genome-Wide Analysis of DNA Methylation and Acute Coronary SyndromeCirculation Research201770
40High-mobility group box 1 promotes early acute allograft rejection by enhancing IL-6-dependent Th17 alloreactive responseLaboratory Investigation201169
41The Transcription Factor TCF1 Preserves the Effector Function of Exhausted CD8 T Cells During Chronic Viral InfectionFrontiers in Immunology201966
42Heme oxygenase-1 upregulation significantly inhibits TNF-α and Hmgb1 releasing and attenuates lipopolysaccharide-induced acute lung injury in miceInternational Immunopharmacology200864
43Expression and significance of HMGB1, TLR4 and NF-κB p65 in human epidermal tumorsBMC Cancer201364
44The effect of HMGB1 on the clinicopathological and prognostic features of non-small cell lung cancerOncotarget201664
45Brg-1 targeting of novel miR550a-5p/RNF43/Wnt signaling axis regulates colorectal cancer metastasisOncogene201664
46Cardioprotective Role of Myeloid-Derived Suppressor Cells in Heart FailureCirculation201864
47IL-33 Prolongs Murine Cardiac Allograft Survival Through Induction of TH2-Type Immune DeviationTransplantation201063
48Transmembrane TNF-alpha promotes chemoresistance in breast cancer cellsOncogene201863
49Transmembrane TNF-α mediates “forward” and “reverse” signaling, inducing cell death or survival via the NF-κB pathway in Raji Burkitt lymphoma cellsJournal of Leukocyte Biology200862
50Anti-inflammatory effects of triptolide by inhibiting the NF-κB signalling pathway in LPS-induced acute lung injury in a murine modelMolecular Medicine Reports201460