| # | Title | Journal | Year | Citations |
|---|
| 1 | Chondrogenic Differentiation of Cultured Human Mesenchymal Stem Cells from Marrow | Tissue Engineering | 1998 | 1,179 |
| 2 | Ophthalmic drug delivery systems—Recent advances | Progress in Retinal and Eye Research | 1998 | 579 |
| 3 | Combinatorial Photothermal and Immuno Cancer Therapy Using Chitosan-Coated Hollow Copper Sulfide Nanoparticles | ACS Nano | 2014 | 472 |
| 4 | Oxidative Stress as a Mechanism of Chronic Cadmium-Induced Hepatotoxicity and Renal Toxicity and Protection by Antioxidants | Toxicology and Applied Pharmacology | 1999 | 373 |
| 5 | The Effect of Molecular Rapid Diagnostic Testing on Clinical Outcomes in Bloodstream Infections: A Systematic Review and Meta-analysis | Clinical Infectious Diseases | 2017 | 365 |
| 6 | Black Sea sterol—a molecular fossil for dinoflagellate blooms | Nature | 1979 | 331 |
| 7 | Hypolipidemic, Antioxidant, and Antiinflammatory Activities of Microalgae Spirulina | Cardiovascular Therapeutics | 2010 | 313 |
| 8 | Combretastatin A-4 Analogues as Antimitotic Antitumor Agents | Current Medicinal Chemistry | 2003 | 311 |
| 9 | A Comparative Study of Hollow Copper Sulfide Nanoparticles and Hollow Gold Nanospheres on Degradability and Toxicity | ACS Nano | 2013 | 259 |
| 10 | Delivering safer immunotherapies for cancer | Advanced Drug Delivery Reviews | 2017 | 233 |
| 11 | MICROALGAL METABOLITES: A New Perspective | Annual Review of Microbiology | 1996 | 225 |
| 12 | Oxytocin by intranasal and intravenous routes reaches the cerebrospinal fluid in rhesus macaques: determination using a novel oxytocin assay | Molecular Psychiatry | 2018 | 201 |
| 13 | Protein pyrophosphorylation by inositol pyrophosphates is a posttranslational event | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 189 |
| 14 | Secondary Metabolites Produced by the Marine Bacterium Halobacillus salinus That Inhibit Quorum Sensing-Controlled Phenotypes in Gram-Negative Bacteria | Applied and Environmental Microbiology | 2009 | 185 |
| 15 | Behavioral evidence for dopaminergic supersensitivity after chronic haloperidol | Life Sciences | 1974 | 184 |
| 16 | Typologies of Alcohol Dependence. From Jellinek to Genetics and Beyond | Neuropsychology Review | 2009 | 173 |
| 17 | Pomegranate’s Neuroprotective Effects against Alzheimer’s Disease Are Mediated by Urolithins, Its Ellagitannin-Gut Microbial Derived Metabolites | ACS Chemical Neuroscience | 2016 | 167 |
| 18 | The Management of Depression in Older Nursing Home Residents | Journal of the American Geriatrics Society | 2002 | 154 |
| 19 | Design and testing in vitro of a bioadhesive and floating drug delivery system for oral application | International Journal of Pharmaceutics | 1994 | 153 |
| 20 | Maple Syrup Phytochemicals Include Lignans, Coumarins, a Stilbene, and Other Previously Unreported Antioxidant Phenolic Compounds | Journal of Agricultural and Food Chemistry | 2010 | 152 |
| 21 | Microalgal metabolites | Current Opinion in Microbiology | 2003 | 151 |
| 22 | A Review of Combination Antimicrobial Therapy for Enterococcus faecalis Bloodstream Infections and Infective Endocarditis | Clinical Infectious Diseases | 2018 | 150 |
| 23 | Prevalence of autosomal dominant polycystic kidney disease in the European Union | Nephrology Dialysis Transplantation | 2017 | 139 |
| 24 | Transformation of paralytic shellfish toxins as demonstrated in scallop homogenates | Science | 1981 | 136 |
| 25 | pHLIP peptide targets nanogold particles to tumors | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 135 |
| 26 | Impairment of TrkB-PSD-95 Signaling in Angelman Syndrome | PLoS Biology | 2013 | 134 |
| 27 | Kaempferol inhibits IL-1β-induced proliferation of rheumatoid arthritis synovial fibroblasts and the production of COX-2, PGE2 and MMPs | International Journal of Molecular Medicine | 2013 | 132 |
| 28 | Synthesis and Characterization of N-Demethylated Metabolites of Malachite Green and Leucomalachite Green | Chemical Research in Toxicology | 2003 | 130 |
| 29 | Applications of alginate microspheres in therapeutics delivery and cell culture: Past, present and future | International Journal of Pharmaceutics | 2019 | 126 |
| 30 | A Small Molecule Targeting Mutagenic Translesion Synthesis Improves Chemotherapy | Cell | 2019 | 126 |
| 31 | Effects of Fruit Ellagitannin Extracts, Ellagic Acid, and Their Colonic Metabolite, Urolithin A, on Wnt Signaling | Journal of Agricultural and Food Chemistry | 2010 | 124 |
| 32 | Stages of change for adherence with medication regimens for chronic disease: Development and validation of a measure | Clinical Therapeutics | 2000 | 122 |
| 33 | Brain Human Monoclonal Autoantibody from Sydenham Chorea Targets Dopaminergic Neurons in Transgenic Mice and Signals Dopamine D2 Receptor: Implications in Human Disease | Journal of Immunology | 2013 | 122 |
| 34 | Evaluation of Polyphenol Anthocyanin-Enriched Extracts of Blackberry, Black Raspberry, Blueberry, Cranberry, Red Raspberry, and Strawberry for Free Radical Scavenging, Reactive Carbonyl Species Trapping, Anti-Glycation, Anti-β-Amyloid Aggregation, and Microglial Neuroprotective Effects | International Journal of Molecular Sciences | 2018 | 122 |
| 35 | Effect of apomorphine and nigrostriatal lesions on aggression and striatal dopamine turnover during morphine withdrawal: Evidence for dopaminergic supersensitivity in protracted abstinence | Psychopharmacology | 1974 | 119 |
| 36 | Eugenia jambolana Lam. Berry Extract Inhibits Growth and Induces Apoptosis of Human Breast Cancer but Not Non-Tumorigenic Breast Cells | Journal of Agricultural and Food Chemistry | 2009 | 119 |
| 37 | Effect of dopaminergic stimulation or blockade on morphine-withdrawal aggression | Psychopharmacology | 1973 | 117 |
| 38 | Therapeutic Effects of Guggul and Its Constituent Guggulsterone: Cardiovascular Benefits | Cardiovascular Drug Reviews | 2007 | 113 |
| 39 | Pharmacodynamics and pharmacokinetics of antibiotics with special reference to the fluoroquinolones | American Journal of Medicine | 1991 | 112 |
| 40 | Controlled release of drugs from injectable in situ formed biodegradable PLGA microspheres: effect of various formulation variables | European Journal of Pharmaceutics and Biopharmaceutics | 2000 | 105 |
| 41 | Distribution of Cyclosporin in Organ Transplant Recipients | Clinical Pharmacokinetics | 2002 | 105 |
| 42 | Pharmacokinetics of Stavudine in Patients with AIDS or AIDS-Related Complex | Journal of Infectious Diseases | 1992 | 103 |
| 43 | Circulating microRNAs in Pancreatic Juice as Candidate Biomarkers of Pancreatic Cancer | Journal of Cancer | 2014 | 103 |
| 44 | Further Investigation into Maple Syrup Yields 3 New Lignans, a New Phenylpropanoid, and 26 Other Phytochemicals | Journal of Agricultural and Food Chemistry | 2011 | 102 |
| 45 | Identification and Bioactivities of Resveratrol Oligomers and Flavonoids from Carex folliculata Seeds | Journal of Agricultural and Food Chemistry | 2009 | 100 |
| 46 | Design and Biological Evaluation of Cell-Penetrating Peptide–Doxorubicin Conjugates as Prodrugs | Molecular Pharmaceutics | 2013 | 99 |
| 47 | Opioid Use Disorder and the COVID 19 Pandemic: A Call to Sustain Regulatory Easements and Further Expand Access to Treatment | Substance Abuse | 2020 | 99 |
| 48 | Physicochemical Properties, Biotransformation, and Transport Pathways of Established and Newly Approved Medications: A Systematic Review of the Top 200 Most Prescribed Drugs vs. the FDA-Approved Drugs Between 2005 and 2016 | Clinical Pharmacokinetics | 2019 | 98 |
| 49 | Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum | JAMA Neurology | 2022 | 97 |
| 50 | Angiotensin II type 1 receptor antagonists inhibit cell proliferation and angiogenesis in breast cancer | Cancer Letters | 2013 | 96 |
