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Top Articles

#TitleJournalYearCitations
1CCR7 Coordinates the Primary Immune Response by Establishing Functional Microenvironments in Secondary Lymphoid OrgansCell19992,122
2A Putative Chemokine Receptor, BLR1, Directs B Cell Migration to Defined Lymphoid Organs and Specific Anatomic Compartments of the SpleenCell19961,059
3Molecular mechanisms and cellular functions of cGAS–STING signallingNature Reviews Molecular Cell Biology2020846
4The Hair Follicle as a Dynamic MiniorganCurrent Biology2009814
5Genome-wide, large-scale production of mutant mice by ENU mutagenesisNature Genetics2000658
6Temporal Control of Mammalian Cortical Neurogenesis by m6A MethylationCell2017567
7Modulation of protein properties in living cells using nanobodiesNature Structural and Molecular Biology2010494
8A new system for naming ribosomal proteinsCurrent Opinion in Structural Biology2014481
9Structures of the human and Drosophila 80S ribosomeNature2013474
10CCMpred—fast and precise prediction of protein residue–residue contacts from correlated mutationsBioinformatics2014387
11The epidermal growth factor receptor ligands at a glanceJournal of Cellular Physiology2009363
12cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein–DNA laddersNature2017346
13Consistent success in life-supporting porcine cardiac xenotransplantationNature2018340
14Optimized ratiometric calcium sensors for functional in vivo imaging of neurons and T lymphocytesNature Methods2014319
15Architecture of the RNA Polymerase II-TFIIS Complex and Implications for mRNA CleavageCell2003298
16Epitope interactions of monoclonal antibodies targeting CD20 and their relationship to functional propertiesMAbs2013280
17A pathway coordinated by DELE1 relays mitochondrial stress to the cytosolNature2020276
18Cryo-EM structure of the ribosome–SecYE complex in the membrane environmentNature Structural and Molecular Biology2011264
19Glycine 384 is required for presenilin-1 function and is conserved in bacterial polytopic aspartyl proteasesNature Cell Biology2000263
20Recognition of RNA polymerase II carboxy-terminal domain by 3′-RNA-processing factorsNature2004260
21Structure and function of the AAA+ nucleotide binding pocketBiochimica Et Biophysica Acta - Molecular Cell Research2012245
22Multisubunit RNA polymerasesCurrent Opinion in Structural Biology2002224
23Overexpression of Insulin-Like Growth Factor-Binding Protein-2 in Transgenic Mice Reduces Postnatal Body Weight GainEndocrinology1999201
24Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-Å resolutionProceedings of the National Academy of Sciences of the United States of America2010196
25Human NLRP1 is a sensor for double-stranded RNAScience2021191
26Structural basis for ATP-dependent chromatin remodelling by the INO80 complexNature2018188
27FMRP Modulates Neural Differentiation through m6A-Dependent mRNA Nuclear ExportCell Reports2019188
28A Common Embryonic Origin of Stem Cells Drives Developmental and Adult NeurogenesisCell2019186
29Following the signal sequence from ribosomal tunnel exit to signal recognition particleNature2006184
30Architecture of the 90S Pre-ribosome: A Structural View on the Birth of the Eukaryotic RibosomeCell2016184
31Comprehensive analysis of β-catenin target genes in colorectal carcinoma cell lines with deregulated Wnt/β-catenin signalingBMC Genomics2014182
32Viral unmasking of cellular 5S rRNA pseudogene transcripts induces RIG-I-mediated immunityNature Immunology2018179
33Introducing the German Mouse Clinic: open access platform for standardized phenotypingNature Methods2005176
34A Key Role for E-cadherin in Intestinal Homeostasis and Paneth Cell MaturationPLoS ONE2010171
35cGAS Senses Human Cytomegalovirus and Induces Type I Interferon Responses in Human Monocyte-Derived CellsPLoS Pathogens2016168
36The bacterial translation stress responseFEMS Microbiology Reviews2014165
37Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclastsNature Communications2014160
38Hypocalcemia and osteopathy in mice with kidney‐specific megalin gene defectFASEB Journal2003154
39Impaired wound healing in transgenic mice overexpressing the activin antagonist follistatin in the epidermisEMBO Journal2001148
40The proline-rich antimicrobial peptide Onc112 inhibits translation by blocking and destabilizing the initiation complexNature Structural and Molecular Biology2015148
41Presenilin-1 differentially facilitates endoproteolysis of the β-amyloid precursor protein and NotchNature Cell Biology2000146
42Monozygotic Twin Model Reveals Novel Embryo-Induced Transcriptome Changes of Bovine Endometrium in the Preattachment Period1Biology of Reproduction2006146
43Beyond Wavy HairsAmerican Journal of Pathology2008146
44Structural basis for sequestration and autoinhibition of cGAS by chromatinNature2020146
45Cross-Link Guided Molecular Modeling with ROSETTAPLoS ONE2013144
46Sebocytes, multifaceted epithelial cells: Lipid production and holocrine secretionInternational Journal of Biochemistry and Cell Biology2010143
47Nascent peptides that block protein synthesis in bacteriaProceedings of the National Academy of Sciences of the United States of America2013137
48DNA double-strand break repair from head to tailCurrent Opinion in Structural Biology2002133
49Target- and Resistance-Based Mechanistic Studies with TP-434, a Novel Fluorocycline AntibioticAntimicrobial Agents and Chemotherapy2012132
50Proline-rich antimicrobial peptides targeting protein synthesisNatural Product Reports2017132