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citing journals

Top Articles

#TitleJournalYearCitations
1Synergy research: Approaching a new generation of phytopharmaceuticalsPhytomedicine2009896
2Tissue Distribution of 5-Hydroxymethylcytosine and Search for Active Demethylation IntermediatesPLoS ONE2010733
3Protein aggregation: Pathways, induction factors and analysisJournal of Pharmaceutical Sciences2009714
4Nucleic Acid Therapeutics Using Polyplexes: A Journey of 50 Years (and Beyond)Chemical Reviews2015495
5Overlooking Subvisible Particles in Therapeutic Protein Products: Gaps That May Compromise Product QualityJournal of Pharmaceutical Sciences2009492
6Farm dust and endotoxin protect against allergy through A20 induction in lung epithelial cellsScience2015483
7Cyld Inhibits Tumor Cell Proliferation by Blocking Bcl-3-Dependent NF-κB SignalingCell2006451
8Purification of polyethylenimine polyplexes highlights the role of free polycations in gene transferJournal of Gene Medicine2004417
9Simple Modifications of Branched PEI Lead to Highly Efficient siRNA Carriers with Low ToxicityBioconjugate Chemistry2008411
10Optimized dispersion of nanoparticles for biological in vitro and in vivo studiesParticle and Fibre Toxicology2008391
11The freezing step in lyophilization: Physico-chemical fundamentals, freezing methods and consequences on process performance and quality attributes of biopharmaceuticalsEuropean Journal of Pharmaceutics and Biopharmaceutics2011376
12Red Wine Polyphenols Enhance Endothelial Nitric Oxide Synthase Expression and Subsequent Nitric Oxide Release From Endothelial CellsCirculation2002366
13Quantification of the Sixth DNA Base Hydroxymethylcytosine in the BrainAngewandte Chemie - International Edition2010350
14Toward Synthetic Viruses: Endosomal pH-Triggered Deshielding of Targeted Polyplexes Greatly Enhances Gene Transfer in vitro and in vivoMolecular Therapy2005310
15Collagen as a carrier for on-site delivery of antibacterial drugsAdvanced Drug Delivery Reviews2003309
16Apoptosis-Inducing Factor Triggered by Poly(ADP-Ribose) Polymerase and Bid Mediates Neuronal Cell Death after Oxygen-Glucose Deprivation and Focal Cerebral IschemiaJournal of Neuroscience2005309
17The Internalization Route Resulting in Successful Gene Expression Depends on both Cell Line and Polyethylenimine Polyplex TypeMolecular Therapy2006289
18Tumor-targeted gene therapy: strategies for the preparation of ligand–polyethylene glycol–polyethylenimine/DNA complexesJournal of Controlled Release2003265
19Breathing Life into Polycations:  Functionalization with pH-Responsive Endosomolytic Peptides and Polyethylene Glycol Enables siRNA DeliveryJournal of the American Chemical Society2008262
20Efficient transgenesis in farm animals by lentiviral vectorsEMBO Reports2003251
21Strategies to Improve DNA Polyplexes for in Vivo Gene Transfer: Will “Artificial Viruses” Be the Answer?Pharmaceutical Research2004218
22Intranasal drug delivery: opportunities and toxicologic challenges during drug developmentDrug Delivery and Translational Research2022198
23Apoptosis-inducing factor is a major contributor to neuronal loss induced by neonatal cerebral hypoxia-ischemiaCell Death and Differentiation2007189
24Potential inaccurate quantitation and sizing of protein aggregates by size exclusion chromatography: Essential need to use orthogonal methods to assure the quality of therapeutic protein productsJournal of Pharmaceutical Sciences2010185
25The use of asymmetrical flow field-flow fractionation in pharmaceutics and biopharmaceuticsEuropean Journal of Pharmaceutics and Biopharmaceutics2004182
26Exploring HCN channels as novel drug targetsNature Reviews Drug Discovery2011181
27Liposome based systems for systemic siRNA delivery: Stability in blood sets the requirements for optimal carrier designJournal of Controlled Release2012175
28Application of the “-Omic-” technologies in phytomedicinePhytomedicine2007172
29Synthesis and Biological Evaluation of a Bioresponsive and Endosomolytic siRNA−Polymer ConjugateMolecular Pharmaceutics2009166
30High susceptibility to fatty liver disease in two-pore channel 2-deficient miceNature Communications2014164
31Silibinin protects mice from T cell-dependent liver injury☆Journal of Hepatology2003160
32Nuclear Translocation of Apoptosis-Inducing Factor after Focal Cerebral IschemiaJournal of Cerebral Blood Flow and Metabolism2004160
33Inhibition of p38 MAPK Activation via Induction of MKP-1Circulation Research2002158
34Quantitation of Aggregate Levels in a Recombinant Humanized Monoclonal Antibody Formulation by Size-Exclusion Chromatography, Asymmetrical Flow Field Flow Fractionation, and Sedimentation VelocityJournal of Pharmaceutical Sciences2007157
35Evolution of the adaptogenic concept from traditional use to medical systems: Pharmacology of stress‐ and aging‐related diseasesMedicinal Research Reviews2021156
36Targeting tumors with non-viral gene delivery systemsDrug Discovery Today2002153
37Phyllanthus amarus has anti-inflammatory potential by inhibition of iNOS, COX-2, and cytokines via the NF-κB pathwayJournal of Hepatology2003152
38Protein stabilization by cyclodextrins in the liquid and dried stateAdvanced Drug Delivery Reviews2011150
39Controlled ice nucleation in the field of freeze-drying: Fundamentals and technology reviewEuropean Journal of Pharmaceutics and Biopharmaceutics2013149
40Generation of Transgenic Cattle by Lentiviral Gene Transfer into Oocytes1Biology of Reproduction2004147
41Lyophilized Drug Product Cake Appearance: What Is Acceptable?Journal of Pharmaceutical Sciences2017145
42Recombinant spider silk particles as drug delivery vehiclesBiomaterials2011137
43Recent advances and further challenges in lyophilizationEuropean Journal of Pharmaceutics and Biopharmaceutics2013135
44An Acetal-Based PEGylation Reagent for pH-Sensitive Shielding of DNA PolyplexesBioconjugate Chemistry2007132
45Surfactant free preparation of biodegradable dendritic polyglycerol nanogels by inverse nanoprecipitation for encapsulation and release of pharmaceutical biomacromoleculesJournal of Controlled Release2013132
46Bid-induced release of AIF from mitochondria causes immediate neuronal cell deathCell Death and Differentiation2008131
47Melittin analogs with high lytic activity at endosomal pH enhance transfection with purified targeted PEI polyplexesJournal of Controlled Release2006127
48A small molecule restores function to TRPML1 mutant isoforms responsible for mucolipidosis type IVNature Communications2014125
49Matrix-loaded biodegradable gelatin nanoparticles as new approach to improve drug loading and deliveryEuropean Journal of Pharmaceutics and Biopharmaceutics2010124
50Mechanical properties and in vitro cell compatibility of hydroxyapatite ceramics with graded pore structureBiomaterials2002122