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Department of Pharmacy
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top-articles
Department of Pharmacy
742
(top 1%)
papers
32.6K
(top 1%)
citations
89
(top 0.1%)
h
-index
145
(top 1%)
g
-index
791
all documents
34.1K
doc citations
3.8K
citing journals
Top Articles
#
Title
Journal
Year
Citations
1
Synergy research: Approaching a new generation of phytopharmaceuticals
Phytomedicine
2009
896
2
Tissue Distribution of 5-Hydroxymethylcytosine and Search for Active Demethylation Intermediates
PLoS ONE
2010
733
3
Protein aggregation: Pathways, induction factors and analysis
Journal of Pharmaceutical Sciences
2009
714
4
Nucleic Acid Therapeutics Using Polyplexes: A Journey of 50 Years (and Beyond)
Chemical Reviews
2015
495
5
Overlooking Subvisible Particles in Therapeutic Protein Products: Gaps That May Compromise Product Quality
Journal of Pharmaceutical Sciences
2009
492
6
Farm dust and endotoxin protect against allergy through A20 induction in lung epithelial cells
Science
2015
483
7
Cyld Inhibits Tumor Cell Proliferation by Blocking Bcl-3-Dependent NF-κB Signaling
Cell
2006
451
8
Purification of polyethylenimine polyplexes highlights the role of free polycations in gene transfer
Journal of Gene Medicine
2004
417
9
Simple Modifications of Branched PEI Lead to Highly Efficient siRNA Carriers with Low Toxicity
Bioconjugate Chemistry
2008
411
10
Optimized dispersion of nanoparticles for biological in vitro and in vivo studies
Particle and Fibre Toxicology
2008
391
11
The freezing step in lyophilization: Physico-chemical fundamentals, freezing methods and consequences on process performance and quality attributes of biopharmaceuticals
European Journal of Pharmaceutics and Biopharmaceutics
2011
376
12
Red Wine Polyphenols Enhance Endothelial Nitric Oxide Synthase Expression and Subsequent Nitric Oxide Release From Endothelial Cells
Circulation
2002
366
13
Quantification of the Sixth DNA Base Hydroxymethylcytosine in the Brain
Angewandte Chemie - International Edition
2010
350
14
Toward Synthetic Viruses: Endosomal pH-Triggered Deshielding of Targeted Polyplexes Greatly Enhances Gene Transfer in vitro and in vivo
Molecular Therapy
2005
310
15
Collagen as a carrier for on-site delivery of antibacterial drugs
Advanced Drug Delivery Reviews
2003
309
16
Apoptosis-Inducing Factor Triggered by Poly(ADP-Ribose) Polymerase and Bid Mediates Neuronal Cell Death after Oxygen-Glucose Deprivation and Focal Cerebral Ischemia
Journal of Neuroscience
2005
309
17
The Internalization Route Resulting in Successful Gene Expression Depends on both Cell Line and Polyethylenimine Polyplex Type
Molecular Therapy
2006
289
18
Tumor-targeted gene therapy: strategies for the preparation of ligand–polyethylene glycol–polyethylenimine/DNA complexes
Journal of Controlled Release
2003
265
19
Breathing Life into Polycations: Functionalization with pH-Responsive Endosomolytic Peptides and Polyethylene Glycol Enables siRNA Delivery
Journal of the American Chemical Society
2008
262
20
Efficient transgenesis in farm animals by lentiviral vectors
EMBO Reports
2003
251
21
Strategies to Improve DNA Polyplexes for in Vivo Gene Transfer: Will “Artificial Viruses” Be the Answer?
Pharmaceutical Research
2004
218
22
Intranasal drug delivery: opportunities and toxicologic challenges during drug development
Drug Delivery and Translational Research
2022
198
23
Apoptosis-inducing factor is a major contributor to neuronal loss induced by neonatal cerebral hypoxia-ischemia
Cell Death and Differentiation
2007
189
24
Potential inaccurate quantitation and sizing of protein aggregates by size exclusion chromatography: Essential need to use orthogonal methods to assure the quality of therapeutic protein products
Journal of Pharmaceutical Sciences
2010
185
25
The use of asymmetrical flow field-flow fractionation in pharmaceutics and biopharmaceutics
European Journal of Pharmaceutics and Biopharmaceutics
2004
182
26
Exploring HCN channels as novel drug targets
Nature Reviews Drug Discovery
2011
181
27
Liposome based systems for systemic siRNA delivery: Stability in blood sets the requirements for optimal carrier design
Journal of Controlled Release
2012
175
28
Application of the “-Omic-” technologies in phytomedicine
Phytomedicine
2007
172
29
Synthesis and Biological Evaluation of a Bioresponsive and Endosomolytic siRNA−Polymer Conjugate
Molecular Pharmaceutics
2009
166
30
High susceptibility to fatty liver disease in two-pore channel 2-deficient mice
Nature Communications
2014
164
31
Silibinin protects mice from T cell-dependent liver injury☆
Journal of Hepatology
2003
160
32
Nuclear Translocation of Apoptosis-Inducing Factor after Focal Cerebral Ischemia
Journal of Cerebral Blood Flow and Metabolism
2004
160
33
Inhibition of p38 MAPK Activation via Induction of MKP-1
Circulation Research
2002
158
34
Quantitation of Aggregate Levels in a Recombinant Humanized Monoclonal Antibody Formulation by Size-Exclusion Chromatography, Asymmetrical Flow Field Flow Fractionation, and Sedimentation Velocity
Journal of Pharmaceutical Sciences
2007
157
35
Evolution of the adaptogenic concept from traditional use to medical systems: Pharmacology of stress‐ and aging‐related diseases
Medicinal Research Reviews
2021
156
36
Targeting tumors with non-viral gene delivery systems
Drug Discovery Today
2002
153
37
Phyllanthus amarus has anti-inflammatory potential by inhibition of iNOS, COX-2, and cytokines via the NF-κB pathway
Journal of Hepatology
2003
152
38
Protein stabilization by cyclodextrins in the liquid and dried state
Advanced Drug Delivery Reviews
2011
150
39
Controlled ice nucleation in the field of freeze-drying: Fundamentals and technology review
European Journal of Pharmaceutics and Biopharmaceutics
2013
149
40
Generation of Transgenic Cattle by Lentiviral Gene Transfer into Oocytes1
Biology of Reproduction
2004
147
41
Lyophilized Drug Product Cake Appearance: What Is Acceptable?
Journal of Pharmaceutical Sciences
2017
145
42
Recombinant spider silk particles as drug delivery vehicles
Biomaterials
2011
137
43
Recent advances and further challenges in lyophilization
European Journal of Pharmaceutics and Biopharmaceutics
2013
135
44
An Acetal-Based PEGylation Reagent for pH-Sensitive Shielding of DNA Polyplexes
Bioconjugate Chemistry
2007
132
45
Surfactant free preparation of biodegradable dendritic polyglycerol nanogels by inverse nanoprecipitation for encapsulation and release of pharmaceutical biomacromolecules
Journal of Controlled Release
2013
132
46
Bid-induced release of AIF from mitochondria causes immediate neuronal cell death
Cell Death and Differentiation
2008
131
47
Melittin analogs with high lytic activity at endosomal pH enhance transfection with purified targeted PEI polyplexes
Journal of Controlled Release
2006
127
48
A small molecule restores function to TRPML1 mutant isoforms responsible for mucolipidosis type IV
Nature Communications
2014
125
49
Matrix-loaded biodegradable gelatin nanoparticles as new approach to improve drug loading and delivery
European Journal of Pharmaceutics and Biopharmaceutics
2010
124
50
Mechanical properties and in vitro cell compatibility of hydroxyapatite ceramics with graded pore structure
Biomaterials
2002
122
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