| # | Title | Journal | Year | Citations |
|---|
| 1 | Discovery of the ergothioneine transporter | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 465 |
| 2 | Clinical consequences of cytochrome P450 2C9 polymorphisms | Clinical Pharmacology and Therapeutics | 2005 | 396 |
| 3 | Effects of chronic atrial fibrillation on gap junction distribution in human and rat atria | Journal of the American College of Cardiology | 2001 | 277 |
| 4 | Increased Availability and Open Probability of Single L-Type Calcium Channels From Failing Compared With Nonfailing Human Ventricle | Circulation | 1998 | 247 |
| 5 | Mechanisms of [Ca2+]i Transient Decrease in Cardiomyopathy of db/db Type 2 Diabetic Mice | Diabetes | 2006 | 224 |
| 6 | Assessment of CYP1A2 Activity in Clinical Practice: Why, How, and When? | Basic and Clinical Pharmacology and Toxicology | 2005 | 222 |
| 7 | Appropriate Phenotyping Procedures for Drug Metabolizing Enzymes and Transporters in Humans and Their Simultaneous Use in the “Cocktail” Approach | Clinical Pharmacology and Therapeutics | 2007 | 220 |
| 8 | Dietary Sources and Antioxidant Effects of Ergothioneine | Journal of Agricultural and Food Chemistry | 2007 | 217 |
| 9 | Pharmacokinetics of clopidogrel after administration of a high loading dose | Thrombosis and Haemostasis | 2004 | 215 |
| 10 | Relative potency of proton-pump inhibitors—comparison of effects on intragastric pH | European Journal of Clinical Pharmacology | 2009 | 204 |
| 11 | Time response of cytochrome P450 1A2 activity on cessation of heavy smoking*1 | Clinical Pharmacology and Therapeutics | 2004 | 192 |
| 12 | Should We Use N -Acetyltransferase Type 2 Genotyping To Personalize Isoniazid Doses? | Antimicrobial Agents and Chemotherapy | 2005 | 187 |
| 13 | Problem‐based learning versus lecture‐based learning in a course of basic pharmacology: a controlled, randomized study | Medical Education | 1999 | 180 |
| 14 | Clinical Pharmacokinetics of Tyrosine Kinase Inhibitors | Clinical Pharmacokinetics | 2011 | 163 |
| 15 | Influence of Processing Parameters on Acrylamide Formation during Frying of Potatoes | Journal of Agricultural and Food Chemistry | 2004 | 156 |
| 16 | Impaired bioavailability of clopidogrel in patients with a ST-segment elevation myocardial infarction | Thrombosis Research | 2008 | 153 |
| 17 | Pharmacogenetics-based therapeutic recommendations — ready for clinical practice? | Nature Reviews Drug Discovery | 2005 | 147 |
| 18 | Evaluation of probe drugs and pharmacokinetic metrics for CYP2D6 phenotyping | European Journal of Clinical Pharmacology | 2007 | 147 |
| 19 | Aspirin induces nitric oxide release from vascular endothelium: a novel mechanism of action | British Journal of Pharmacology | 2004 | 146 |
| 20 | Toxicokinetics of Acrylamide in Humans after Ingestion of a Defined Dose in a Test Meal to Improve Risk Assessment for Acrylamide Carcinogenicity | Cancer Epidemiology Biomarkers and Prevention | 2006 | 139 |
| 21 | Role of microglia in neuronal degeneration and regeneration | Seminars in Immunopathology | 2009 | 126 |
| 22 | The clinical role of genetic polymorphisms in drug-metabolizing enzymes | Pharmacogenomics Journal | 2008 | 124 |
| 23 | Pharmacogenomics Education: International Society of Pharmacogenomics Recommendations for Medical, Pharmaceutical, and Health Schools Deans of Education | Pharmacogenomics Journal | 2005 | 119 |
| 24 | Functional Properties of a Newly Identified C-terminal Splice Variant of Cav1.3 L-type Ca2+ Channels | Journal of Biological Chemistry | 2011 | 118 |
| 25 | Reaction rate constants of superoxide scavenging by plant antioxidants | Free Radical Biology and Medicine | 2003 | 100 |
| 26 | Agmatine Is Efficiently Transported by Non-Neuronal Monoamine Transporters Extraneuronal Monoamine Transporter (EMT) and Organic Cation Transporter 2 (OCT2) | Journal of Pharmacology and Experimental Therapeutics | 2003 | 95 |
| 27 | Which platelet function test is suitable to monitor clopidogrel responsiveness? A pharmacokinetic analysis on the active metabolite of clopidogrel | Journal of Thrombosis and Haemostasis | 2010 | 95 |
| 28 | Clinical Pharmacokinetics of Tyrosine Kinase Inhibitors | Clinical Pharmacokinetics | 2011 | 95 |
| 29 | Pharmacogenetics of Oral Anticoagulants | Clinical Pharmacokinetics | 2008 | 94 |
| 30 | Downregulation of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) in human hepatocellular carcinoma and their prognostic significance | BMC Cancer | 2012 | 94 |
| 31 | Acid sphingomyelinase is a key regulator of cytotoxic granule secretion by primary T lymphocytes | Nature Immunology | 2009 | 89 |
| 32 | Nitric Oxide Formation and Corresponding Relaxation of Porcine Coronary Arteries Induced by Plant Phenols: Essential Structural Features | Journal of Cardiovascular Pharmacology | 2002 | 86 |
| 33 | Clinical Pharmacokinetics of Trospium Chloride | Clinical Pharmacokinetics | 2005 | 85 |
| 34 | Development of a new G-CSF product based on biosimilarity assessment | Annals of Oncology | 2010 | 85 |
| 35 | Absorption, Pharmacokinetics, and Safety of Triclosan after Dermal Administration | Antimicrobial Agents and Chemotherapy | 2010 | 83 |
| 36 | The ergothioneine transporter controls and indicates ergothioneine activity — A review | Preventive Medicine | 2012 | 81 |
| 37 | Extraneuronal Monoamine Transporter and Organic Cation Transporters 1 and 2: A Review of Transport Efficiency | | 2006 | 78 |
| 38 | Effect of an Antiretroviral Regimen Containing Ritonavir Boosted Lopinavir on Intestinal and Hepatic CYP3A, CYP2D6 and P-glycoprotein in HIV-infected Patients | Clinical Pharmacology and Therapeutics | 2008 | 76 |
| 39 | Dermal absorption of permethrin following topical administration | European Journal of Clinical Pharmacology | 2005 | 75 |
| 40 | The Carnitine Transporter SLC22A5 Is Not a General Drug Transporter, but It Efficiently Translocates Mildronate | Drug Metabolism and Disposition | 2009 | 71 |
| 41 | Factors Influencing Pharmacokinetics of Prophylactic Posaconazole in Patients Undergoing Allogeneic Stem Cell Transplantation | Antimicrobial Agents and Chemotherapy | 2010 | 70 |
| 42 | Cytochrome P 450 2C9 phenotyping using low-dose tolbutamide | European Journal of Clinical Pharmacology | 2004 | 66 |
| 43 | Modulation of Human Platelet Aggregation by the Phosphodiesterase Type 5 Inhibitor Sildenafil | Journal of Cardiovascular Pharmacology | 2001 | 64 |
| 44 | Probing the substrate specificity of the ergothioneine transporter with methimazole, hercynine, and organic cations | Biochemical Pharmacology | 2007 | 64 |
| 45 | OAT2 catalyses efflux of glutamate and uptake of orotic acid | Biochemical Journal | 2011 | 62 |
| 46 | In vivo Role of Cytochrome P450 2E1 and Glutathione-S-Transferase Activity for Acrylamide Toxicokinetics in Humans | Cancer Epidemiology Biomarkers and Prevention | 2009 | 61 |
| 47 | Plasma 4β-Hydroxycholesterol: An Endogenous CYP3A Metric? | Clinical Pharmacology and Therapeutics | 2009 | 61 |
| 48 | Profiling of mercapturic acids of acrolein and acrylamide in human urine after consumption of potato crisps* | Molecular Nutrition and Food Research | 2012 | 61 |
| 49 | Cardioprotection specific for the G protein Gi2 in chronic adrenergic signaling through 2-adrenoceptors | Proceedings of the National Academy of Sciences of the United States of America | 2003 | 59 |
| 50 | Increased Expression of the Auxiliary β2-subunit of Ventricular L-type Ca2+ Channels Leads to Single-Channel Activity Characteristic of Heart Failure | PLoS ONE | 2007 | 57 |
