# | Title | Journal | Year | Citations |
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1 | Identification of the molecular basis of doxorubicin-induced cardiotoxicity | Nature Medicine | 2012 | 1,491 |
2 | Cardiovascular Complications of Cancer Therapy | Journal of the American College of Cardiology | 2009 | 1,083 |
3 | Human mesenchymal stem cells exert potent antitumorigenic effects in a model of Kaposi's sarcoma | Journal of Experimental Medicine | 2006 | 700 |
4 | Reversibility of Trastuzumab-Related Cardiotoxicity: New Insights Based on Clinical Course and Response to Medical Treatment | Journal of Clinical Oncology | 2005 | 640 |
5 | SUMO-Specific Protease 1 Is Essential for Stabilization of HIF1α during Hypoxia | Cell | 2007 | 535 |
6 | Cancer drugs and the heart: importance and management | European Heart Journal | 2013 | 372 |
7 | Validation and Potential Mechanisms of Red Cell Distribution Width as a Prognostic Marker in Heart Failure | Journal of Cardiac Failure | 2010 | 344 |
8 | Cardiovascular Complications of Cancer Therapy | Journal of the American College of Cardiology | 2017 | 298 |
9 | Immune Checkpoint Inhibitor Myocarditis: Pathophysiological Characteristics, Diagnosis, and Treatment | Journal of the American Heart Association | 2020 | 240 |
10 | Cardiovascular Complications of Cancer Therapy | Journal of the American College of Cardiology | 2017 | 221 |
11 | A proline-90 residue unique to SUMO-4 prevents maturation and sumoylation | Biochemical and Biophysical Research Communications | 2005 | 194 |
12 | Regulation of DNA Repair through DeSUMOylation and SUMOylation of Replication Protein A Complex | Molecular Cell | 2010 | 185 |
13 | Cardiovascular toxicity following sunitinib therapy in metastatic renal cell carcinoma: a multicenter analysis | Annals of Oncology | 2009 | 180 |
14 | Topoisomerase 2β: A Promising Molecular Target for Primary Prevention of Anthracycline-Induced Cardiotoxicity | Clinical Pharmacology and Therapeutics | 2013 | 179 |
15 | Radiation-Induced Endothelial Vascular Injury | JACC Basic To Translational Science | 2018 | 177 |
16 | SENP3 is responsible for HIF-1 transactivation under mild oxidative stress via p300 de-SUMOylation | EMBO Journal | 2009 | 172 |
17 | Cardiomyocyte PDGFR-β signaling is an essential component of the mouse cardiac response to load-induced stress | Journal of Clinical Investigation | 2010 | 170 |
18 | Radiation-Induced Heart Disease: A Clinical Update | Cardiology Research and Practice | 2011 | 161 |
19 | Pertuzumab, trastuzumab, and standard anthracycline- and taxane-based chemotherapy for the neoadjuvant treatment of patients with HER2-positive localized breast cancer (BERENICE): a phase II, open-label, multicenter, multinational cardiac safety study | Annals of Oncology | 2018 | 150 |
20 | Cardiac Tolerability of Pertuzumab Plus Trastuzumab Plus Docetaxel in Patients With HER2‐Positive Metastatic Breast Cancer in CLEOPATRA: A Randomized, Double‐Blind, Placebo‐Controlled Phase III Study | Oncologist | 2013 | 137 |
21 | Primary cardiac tumors | Texas Heart Institute Journal | 2011 | 111 |
22 | Anthracycline cardiotoxicity | Expert Opinion on Drug Safety | 2006 | 108 |
23 | Treatment and Outcomes of Acute Coronary Syndrome in the Cancer Population | Clinical Cardiology | 2012 | 105 |
24 | SUMO-Specific Protease 1 Is Critical for Early Lymphoid Development through Regulation of STAT5 Activation | Molecular Cell | 2012 | 96 |
25 | Outcomes of Cancer Patients Undergoing Percutaneous Pericardiocentesis for Pericardial Effusion | Journal of the American College of Cardiology | 2015 | 93 |
26 | SENP1 Induces Prostatic Intraepithelial Neoplasia through Multiple Mechanisms | Journal of Biological Chemistry | 2010 | 92 |
27 | SENP3-mediated De-conjugation of SUMO2/3 from Promyelocytic Leukemia Is Correlated with Accelerated Cell Proliferation under Mild Oxidative Stress | Journal of Biological Chemistry | 2010 | 92 |
28 | Improved Outcomes With the Evolution of a Neoadjuvant Chemotherapy Approach to Right Heart Sarcoma | Annals of Thoracic Surgery | 2017 | 92 |
29 | Radiotherapy-Induced Malfunction in Contemporary Cardiovascular Implantable Electronic Devices | JAMA Oncology | 2015 | 91 |
30 | Acute myocardial infarction treatments and outcomes in 6.5 million patients with a current or historical diagnosis of cancer in the USA | European Heart Journal | 2020 | 87 |
31 | Radiation-Induced Cardiovascular Disease: A Clinical Perspective | Frontiers in Cardiovascular Medicine | 2017 | 84 |
32 | The Evolving Immunotherapy Landscape and the Epidemiology, Diagnosis, and Management of Cardiotoxicity | JACC: CardioOncology | 2021 | 80 |
33 | Cardiac and cardiovascular toxicity of nonanthracycline anticancer drugs | Expert Review of Anticancer Therapy | 2006 | 75 |
34 | Endothelial-to-Osteoblast Conversion Generates Osteoblastic Metastasis of Prostate Cancer | Developmental Cell | 2017 | 75 |
35 | First-in-human study of pbi-05204, an oleander-derived inhibitor of akt, fgf-2, nf-κΒ and p70s6k, in patients with advanced solid tumors | Investigational New Drugs | 2014 | 73 |
36 | NEDD8 protein is involved in ubiquitinated inclusion bodies | Journal of Pathology | 2003 | 72 |
37 | Short and long term radiation induced cardiovascular disease in patients with cancer | Clinical Cardiology | 2017 | 70 |
38 | Cardiac Tumors in a Tertiary Care Cancer Hospital: Clinical Features, Echocardiographic Findings, Treatment and Outcomes | Heart International | 2012 | 69 |
39 | Therapy Insight: management of cardiovascular disease in patients with cancer and cardiac complications of cancer therapy | Nature Clinical Practice Oncology | 2008 | 68 |
40 | The Utility of Point-of-Care Biomarkers to Detect Cardiotoxicity During Anthracycline Chemotherapy: A Feasibility Study | Journal of Cardiac Failure | 2016 | 68 |
41 | Challenges Associated with Tyrosine Kinase Inhibitor Therapy for Metastatic Thyroid Cancer | Journal of Thyroid Research | 2011 | 67 |
42 | Vascular complications of selected cancer therapies | Nature Clinical Practice Cardiovascular Medicine | 2008 | 66 |
43 | Analysis of carfilzomib cardiovascular safety profile across relapsed and/or refractory multiple myeloma clinical trials | Blood Advances | 2018 | 66 |
44 | Clinical Strategy for the Diagnosis and Treatment of Immune Checkpoint Inhibitor–Associated Myocarditis | JAMA Cardiology | 2021 | 64 |
45 | Differential expression of SUMO-specific protease 7 variants regulates epithelial–mesenchymal transition | Proceedings of the National Academy of Sciences of the United States of America | 2012 | 63 |
46 | Incidence and Onset of Severe Cardiac Events After Radiotherapy for Esophageal Cancer | Journal of Thoracic Oncology | 2020 | 63 |
47 | Malfunctions of Implantable Cardiac Devices in Patients Receiving Proton Beam Therapy: Incidence and Predictors | International Journal of Radiation Oncology Biology Physics | 2013 | 60 |
48 | Cancer as a Risk Factor for Cardiovascular Disease | Current Oncology Reports | 2017 | 60 |
49 | Prospective Exploratory Analysis of Cardiac Biomarkers and Electrocardiogram Abnormalities in Patients Receiving Thoracic Radiation Therapy with High-Dose Heart Exposure | Journal of Thoracic Oncology | 2014 | 59 |
50 | β-Catenin Links von Hippel-Lindau to Aurora Kinase A and Loss of Primary Cilia in Renal Cell Carcinoma | Journal of the American Society of Nephrology: JASN | 2015 | 59 |