| # | Title | Journal | Year | Citations |
|---|
| 1 | Signal transduction by lymphocyte antigen receptors | Cell | 1994 | 2,108 |
| 2 | Hepatitis B Virus Infection — Natural History and Clinical Consequences | New England Journal of Medicine | 2004 | 2,075 |
| 3 | Diversity and heritability of the maize rhizosphere microbiome under field conditions | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 1,594 |
| 4 | Host Defense Mechanisms Triggered by Microbial Lipoproteins Through Toll-Like Receptors | Science | 1999 | 1,506 |
| 5 | C3d of Complement as a Molecular Adjuvant: Bridging Innate and Acquired Immunity | Science | 1996 | 1,133 |
| 6 | Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients | Nature Medicine | 1999 | 1,033 |
| 7 | CD69 acts downstream of interferon-α/β to inhibit S1P1 and lymphocyte egress from lymphoid organs | Nature | 2006 | 1,014 |
| 8 | Germinal-Center Organization and Cellular Dynamics | Immunity | 2007 | 838 |
| 9 | Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF- B control | Proceedings of the National Academy of Sciences of the United States of America | 1997 | 834 |
| 10 | Promotion of Lymphocyte Egress into Blood and Lymph by Distinct Sources of Sphingosine-1-Phosphate | Science | 2007 | 826 |
| 11 | Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells | Nature Immunology | 2007 | 809 |
| 12 | Human Circulating PD-1+CXCR3−CXCR5+ Memory Tfh Cells Are Highly Functional and Correlate with Broadly Neutralizing HIV Antibody Responses | Immunity | 2013 | 790 |
| 13 | CHEMOKINES, SPHINGOSINE-1-PHOSPHATE, AND CELL MIGRATION IN SECONDARY LYMPHOID ORGANS | Annual Review of Immunology | 2005 | 772 |
| 14 | Lymphocyte Sequestration Through S1P Lyase Inhibition and Disruption of S1P Gradients | Science | 2005 | 732 |
| 15 | Direct observation of ligand recognition by T cells | Nature | 2002 | 725 |
| 16 | Association of Transcriptionally Silent Genes with Ikaros Complexes at Centromeric Heterochromatin | Cell | 1997 | 724 |
| 17 | Sphingosine-1-Phosphate and Lymphocyte Egress from Lymphoid Organs | Annual Review of Immunology | 2012 | 708 |
| 18 | Imaging of Germinal Center Selection Events During Affinity Maturation | Science | 2007 | 701 |
| 19 | Complex lipid determines tissue-specific replication of Mycobacterium tuberculosis in mice | Nature | 1999 | 692 |
| 20 | Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens | Nature | 1991 | 649 |
| 21 | Germinal center dark and light zone organization is mediated by CXCR4 and CXCR5 | Nature Immunology | 2004 | 649 |
| 22 | Chemokines as regulators of T cell differentiation | Nature Immunology | 2001 | 643 |
| 23 | An inducible bundle-forming pilus of enteropathogenic Escherichia coli | Science | 1991 | 641 |
| 24 | Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product. | Proceedings of the National Academy of Sciences of the United States of America | 1992 | 612 |
| 25 | Origins of Highly Mosaic Mycobacteriophage Genomes | Cell | 2003 | 609 |
| 26 | Failure of B-cell differentiation in mice lacking the transcription factor EBF | Nature | 1995 | 603 |
| 27 | A Novel Mycolic Acid Cyclopropane Synthetase Is Required for Cording, Persistence, and Virulence of Mycobacterium tuberculosis | Molecular Cell | 2000 | 599 |
| 28 | A Coordinated Change in Chemokine Responsiveness Guides Plasma Cell Movements | Journal of Experimental Medicine | 2001 | 589 |
| 29 | PDGF β-receptor stimulates tyrosine phosphorylation of GAP and association of GAP with a signaling complex | Cell | 1990 | 581 |
| 30 | Subcapsular encounter and complement-dependent transport of immune complexes by lymph node B cells | Nature Immunology | 2007 | 576 |
| 31 | CD1d1 Mutant Mice Are Deficient in Natural T Cells That PromptlyProduce IL-4 | Immunity | 1997 | 575 |
| 32 | A Receptor/Cytoskeletal Movement Triggered by Costimulation During T Cell Activation | Science | 1998 | 573 |
| 33 | Signal-induced degradation of I kappa B alpha requires site-specific ubiquitination. | Proceedings of the National Academy of Sciences of the United States of America | 1995 | 543 |
| 34 | Coexpression of the chemokines ELC and SLC by T zone stromal cells and deletion of the ELC gene in the plt/plt mouse | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 540 |
| 35 | B Cell Responses: Cell Interaction Dynamics and Decisions | Cell | 2019 | 540 |
| 36 | The natural killer T-cell ligand α-galactosylceramide prevents autoimmune diabetes in non-obese diabetic mice | Nature Medicine | 2001 | 537 |
| 37 | Exploring drug-induced alterations in gene expression in Mycobacterium tuberculosis by microarray hybridization | Proceedings of the National Academy of Sciences of the United States of America | 1999 | 531 |
| 38 | Reduced Competitiveness of Autoantigen-Engaged B Cells due to Increased Dependence on BAFF | Immunity | 2004 | 529 |
| 39 | Finding a way out: lymphocyte egress from lymphoid organs | Nature Immunology | 2007 | 527 |
| 40 | Balanced responsiveness to chemoattractants from adjacent zones determines B-cell position | Nature | 2002 | 506 |
| 41 | HIV-1 structural gene expression requires binding of the rev trans-activator to its RNA target sequence | Cell | 1990 | 503 |
| 42 | T cell killing does not require the formation of a stable mature immunological synapse | Nature Immunology | 2004 | 496 |
| 43 | Antigen-Engaged B Cells Undergo Chemotaxis toward the T Zone and Form Motile Conjugates with Helper T Cells | PLoS Biology | 2005 | 495 |
| 44 | CXCL13 Is Required for B1 Cell Homing, Natural Antibody Production, and Body Cavity Immunity | Immunity | 2002 | 485 |
| 45 | Elimination of self-reactive B lymphocytes proceeds in two stages: Arrested development and cell death | Cell | 1993 | 483 |
| 46 | Chemokine Requirements for B Cell Entry to Lymph Nodes and Peyer's Patches | Journal of Experimental Medicine | 2002 | 479 |
| 47 | Differing Activities of Homeostatic Chemokines CCL19, CCL21, and CXCL12 in Lymphocyte and Dendritic Cell Recruitment and Lymphoid Neogenesis | Journal of Immunology | 2002 | 475 |
| 48 | Follicular shuttling of marginal zone B cells facilitates antigen transport | Nature Immunology | 2008 | 471 |
| 49 | Hypoimmunogenic derivatives of induced pluripotent stem cells evade immune rejection in fully immunocompetent allogeneic recipients | Nature Biotechnology | 2019 | 470 |
| 50 | Tyrosine phosphatase CD45 is essential for coupling T-cell antigen receptor to the phosphatidyl inositol pathway | Nature | 1990 | 469 |
