| # | Title | Journal | Year | Citations |
|---|
| 1 | Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus | BMC Developmental Biology | 2001 | 2,753 |
| 2 | Neuronal specification in the spinal cord: inductive signals and transcriptional codes | Nature Reviews Genetics | 2000 | 1,878 |
| 3 | A hierarchical approach to all-atom protein loop prediction | Proteins: Structure, Function and Bioinformatics | 2004 | 1,874 |
| 4 | Visualizing an Olfactory Sensory Map | Cell | 1996 | 1,825 |
| 5 | Directed Differentiation of Embryonic Stem Cells into Motor Neurons | Cell | 2002 | 1,622 |
| 6 | DNA interrogation by the CRISPR RNA-guided endonuclease Cas9 | Nature | 2014 | 1,573 |
| 7 | Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters | Nature | 2005 | 1,564 |
| 8 | The antigenic structure of the HIV gp120 envelope glycoprotein | Nature | 1998 | 1,152 |
| 9 | Determination of macromolecular structures from anomalous diffraction of synchrotron radiation | Science | 1991 | 1,150 |
| 10 | A Spatial Map of Olfactory Receptor Expression in the Drosophila Antenna | Cell | 1999 | 1,104 |
| 11 | A Homeodomain Protein Code Specifies Progenitor Cell Identity and Neuronal Fate in the Ventral Neural Tube | Cell | 2000 | 1,065 |
| 12 | On the Role of the Crystal Environment in Determining Protein Side-chain Conformations | Journal of Molecular Biology | 2002 | 1,002 |
| 13 | Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm | Cell | 1995 | 989 |
| 14 | An Olfactory Sensory Map in the Fly Brain | Cell | 2000 | 973 |
| 15 | Topographic organization of embryonic motor neurons defined by expression of LIM homeobox genes | Cell | 1994 | 942 |
| 16 | Pax6 Controls Progenitor Cell Identity and Neuronal Fate in Response to Graded Shh Signaling | Cell | 1997 | 939 |
| 17 | The role of DNA shape in protein–DNA recognition | Nature | 2009 | 918 |
| 18 | Gene Regulation by Transcription Factors and MicroRNAs | Science | 2008 | 842 |
| 19 | Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord | Cell | 1994 | 833 |
| 20 | Two Critical Periods of Sonic Hedgehog Signaling Required for the Specification of Motor Neuron Identity | Cell | 1996 | 818 |
| 21 | Spatial segregation of odorant receptor expression in the mammalian olfactory epithelium | Cell | 1993 | 811 |
| 22 | Two-Photon Calcium Imaging Reveals an Odor-Evoked Map of Activity in the Fly Brain | Cell | 2003 | 752 |
| 23 | Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene | Nature | 1995 | 728 |
| 24 | Vertebrate neurogenesis is counteracted by Sox1–3 activity | Nature Neuroscience | 2003 | 708 |
| 25 | Common Sense about Taste: From Mammals to Insects | Cell | 2009 | 699 |
| 26 | Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling | Nature | 1999 | 687 |
| 27 | Diversity and Pattern in the Developing Spinal Cord | Science | 1996 | 681 |
| 28 | Requirement for RORgamma in Thymocyte Survival and Lymphoid Organ Development | Science | 2000 | 676 |
| 29 | Independent requirement for ISL1 in formation of pancreatic mesenchyme and islet cells | Nature | 1997 | 647 |
| 30 | Rapid grid-based construction of the molecular surface and the use of induced surface charge to calculate reaction field energies: Applications to the molecular systems and geometric objects | Journal of Computational Chemistry | 2002 | 631 |
| 31 | Early stages of motor neuron differentiation revealed by expression of homeobox gene Islet-1 | Science | 1992 | 618 |
| 32 | Crystal structure of core streptavidin determined from multiwavelength anomalous diffraction of synchrotron radiation. | Proceedings of the National Academy of Sciences of the United States of America | 1989 | 602 |
| 33 | Coordinate Regulation of Motor Neuron Subtype Identity and Pan-Neuronal Properties by the bHLH Repressor Olig2 | Neuron | 2001 | 563 |
| 34 | Requirement for the Homeobox Gene Hb9 in the Consolidation of Motor Neuron Identity | Neuron | 1999 | 560 |
| 35 | Odorant Receptors Govern the Formation of a Precise Topographic Map | Cell | 1998 | 558 |
| 36 | Interchromosomal Interactions and Olfactory Receptor Choice | Cell | 2006 | 543 |
| 37 | Spatial Representation of the Glomerular Map in the Drosophila Protocerebrum | Cell | 2002 | 530 |
| 38 | Von Willebrand factor, ADAMTS13, and thrombotic thrombocytopenic purpura | Blood | 2008 | 511 |
| 39 | Binding and stimulation of HIV-1 integrase by a human homolog of yeast transcription factor SNF5 | Science | 1994 | 506 |
| 40 | Structure of human chorionic gonadotropin at 2.6 å resolution from MAD analysis of the selenomethionyl protein | Structure | 1994 | 493 |
| 41 | LIN-12/Notch signaling: lessons from worms and flies | Genes and Development | 1998 | 493 |
| 42 | DC-SIGN-Mediated Internalization of HIV Is Required for Trans-Enhancement of T Cell Infection | Immunity | 2002 | 477 |
| 43 | Progression from Extrinsic to Intrinsic Signaling in Cell Fate Specification | Cell | 1999 | 469 |
| 44 | Semaphorin 3E and Plexin-D1 Control Vascular Pattern Independently of Neuropilins | Science | 2005 | 466 |
| 45 | THE SPECIFICATION OF DORSAL CELL FATES IN THE VERTEBRATE CENTRAL NERVOUS SYSTEM | Annual Review of Neuroscience | 1999 | 464 |
| 46 | Induction of the LIM homeobox gene Lmx1 by WNT6a establishes dorsoventral pattern in the vertebrate limb | Cell | 1995 | 449 |
| 47 | Starvation-Induced Transgenerational Inheritance of Small RNAs in C. elegans | Cell | 2014 | 448 |
| 48 | Piezo2 is the principal mechanotransduction channel for proprioception | Nature Neuroscience | 2015 | 433 |
| 49 | Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core | EMBO Journal | 2003 | 430 |
| 50 | Inhibition of Retroviral RNA Production by ZAP, a CCCH-Type Zinc Finger Protein | Science | 2002 | 411 |
