Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX | Proceedings of the National Academy of Sciences of the United States of America | 2002 | 451 |
Expression of ZAP-70 is associated with increased B-cell receptor signaling in chronic lymphocytic leukemia | Blood | 2002 | 407 |
BID regulation by p53 contributes to chemosensitivity | Nature Cell Biology | 2002 | 336 |
Zebrafish as a cancer model system | Cancer Cell | 2002 | 288 |
The zinc-finger proto-oncogene Gfi-1b is essential for development of the erythroid and megakaryocytic lineages | Genes and Development | 2002 | 184 |
Beta-catenin/Tcf-regulated transcription prior to the midblastula transition | Development (Cambridge) | 2002 | 175 |
Defining characteristics of Types I and II apoptotic cells in response to TRAIL | Neoplasia | 2002 | 161 |
Tissue-specific induction of p53 targets in vivo | Cancer Research | 2002 | 155 |
GATA-factor dependence of the multitype zinc-finger protein FOG-1 for its essential role in megakaryopoiesis | Proceedings of the National Academy of Sciences of the United States of America | 2002 | 152 |
BRCA1 directs a selective p53-dependent transcriptional response towards growth arrest and DNA repair targets | Molecular and Cellular Biology | 2002 | 134 |
Apoptotic threshold is lowered by p53 transactivation of caspase-6 | Proceedings of the National Academy of Sciences of the United States of America | 2002 | 132 |
The mutant p53-conformation modifying drug, CP-31398, can induce apoptosis of human cancer cells and can stabilize wild-type p53 protein | Cancer Biology and Therapy | 2002 | 114 |
Endoplasmic reticulum calcium pool depletion-induced apoptosis is coupled with activation of the death receptor 5 pathway | Oncogene | 2002 | 85 |
BRCA1 transcriptionally regulates damaged DNA binding protein (DDB2) in the DNA repair response following UV-irradiation | Cancer Biology and Therapy | 2002 | 73 |
Portrait of a stem cell | Developmental Cell | 2002 | 50 |
Rac2-deficient mice display perturbed T-cell distribution and chemotaxis, but only minor abnormalities in T(H)1 responses | Immunology and Cell Biology | 2002 | 48 |
A genetic view of iron homeostasis | Seminars in Hematology | 2002 | 37 |
Enhanced sensitivity of G1 arrested human cancer cells suggests a novel therapeutic strategy using a combination of simvastatin and TRAIL | Cell Cycle | 2002 | 37 |
Molecular cloning and developmental expression of Tlx (Hox11) genes in zebrafish (Danio rerio) | Mechanisms of Development | 2002 | 34 |
The use of altered specificity mutants to probe specific protein-protein interactions involved in the activation of GATA-1 target genes | Methods | 2002 | 21 |
The cyclin-dependent kinase inhibitor butyrolactone is a potent inhibitor of p21 (WAF1/CIP1 expression) | Cell Cycle | 2002 | 11 |