Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling | Nature | 2000 | 7.6K |
Signal transduction by the JNK group of MAP kinases | Cell | 2000 | 3.5K |
Two-component signal transduction | Annual Review of Biochemistry | 2000 | 2.5K |
Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin | Annual Review of Biochemistry | 2000 | 2.1K |
Cellular mechanisms of insulin resistance | Journal of Clinical Investigation | 2000 | 1.9K |
Systematic variation in gene expression patterns in human cancer cell lines | Nature Genetics | 2000 | 1.7K |
Genes expressed in human tumor endothelium | Science | 2000 | 1.6K |
Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway | Science | 2000 | 1.5K |
Comparative genomics of the eukaryotes | Science | 2000 | 1.4K |
Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter | Nature | 2000 | 1.3K |
A gene expression database for the molecular pharmacology of cancer | Nature Genetics | 2000 | 1.2K |
Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine | Nature | 2000 | 1.1K |
The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307) | Journal of Biological Chemistry | 2000 | 1.1K |
Neurotoxicity induces cleavage of p35 to p25 by calpain | Nature | 2000 | 891 |
AIDS as a zoonosis: scientific and public health implications | Science | 2000 | 846 |
Drosophila Dscam is an axon guidance receptor exhibiting extraordinary molecular diversity | Cell | 2000 | 838 |
Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXR alpha | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 837 |
tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c | Genes and Development | 2000 | 826 |
Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c | Cell Death and Differentiation | 2000 | 816 |
Role of BAX in the apoptotic response to anticancer agents | Science | 2000 | 767 |
Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors | Science | 2000 | 740 |
Biochemistry, mutagenesis, and oligomerization of DsRed, a red fluorescent protein from coral | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 735 |
Signal transduction cascades regulating fungal development and virulence | Microbiology and Molecular Biology Reviews | 2000 | 709 |
Control of homeostasis of CD8+ memory T cells by opposing cytokines | Science | 2000 | 705 |
Specificities of heparan sulphate proteoglycans in developmental processes | Nature | 2000 | 638 |