| # | Title | Journal | Year | Citations |
|---|
| 1 | Treatment of Sickle Cell Anemia Mouse Model with iPS Cells Generated from Autologous Skin | Science | 2007 | 1,399 |
| 2 | Glycosylation in health and disease | Nature Reviews Nephrology | 2019 | 1,166 |
| 3 | The Biology and Life-Cycle of Human Papillomaviruses | Vaccine | 2012 | 1,042 |
| 4 | ATF4 Is a Substrate of RSK2 and an Essential Regulator of Osteoblast Biology | Cell | 2004 | 749 |
| 5 | Sequestosome 1/p62 Is a Polyubiquitin Chain Binding Protein Involved in Ubiquitin Proteasome Degradation | Molecular and Cellular Biology | 2004 | 624 |
| 6 | Neurological abnormalities in a knock-in mouse model of Huntington's disease | Human Molecular Genetics | 2001 | 528 |
| 7 | DYNAMIC O-LINKED GLYCOSYLATION OF NUCLEAR AND CYTOSKELETAL PROTEINS | Annual Review of Biochemistry | 1997 | 504 |
| 8 | Global Reorganization of Replication Domains During Embryonic Stem Cell Differentiation | PLoS Biology | 2008 | 496 |
| 9 | Histone H3 and H4 Ubiquitylation by the CUL4-DDB-ROC1 Ubiquitin Ligase Facilitates Cellular Response to DNA Damage | Molecular Cell | 2006 | 447 |
| 10 | Discovery of a New Capsular Serotype (6C) within Serogroup 6 ofStreptococcus pneumoniae | Journal of Clinical Microbiology | 2007 | 404 |
| 11 | A KH Domain RNA Binding Protein, KSRP, Promotes ARE-Directed mRNA Turnover by Recruiting the Degradation Machinery | Molecular Cell | 2004 | 390 |
| 12 | c-Myc Is Glycosylated at Threonine 58, a Known Phosphorylation Site and a Mutational Hot Spot in Lymphomas | Journal of Biological Chemistry | 1995 | 365 |
| 13 | Ectopically Expressed CAG Repeats Cause Intranuclear Inclusions and a Progressive Late Onset Neurological Phenotype in the Mouse | Cell | 1997 | 350 |
| 14 | The flying ice cube: Velocity rescaling in molecular dynamics leads to violation of energy equipartition | Journal of Computational Chemistry | 1998 | 347 |
| 15 | Intraflagellar transport is essential for endochondral bone formation | Development (Cambridge) | 2007 | 343 |
| 16 | Expressed Murine and Human CDR-H3 Intervals of Equal Length Exhibit Distinct Repertoires that Differ in their Amino Acid Composition and Predicted Range of Structures | Journal of Molecular Biology | 2003 | 323 |
| 17 | O-Glycosylation of Nuclear and Cytosolic Proteins | Journal of Biological Chemistry | 2000 | 322 |
| 18 | Physical crosslinking of collagen fibers: Comparison of ultraviolet irradiation and dehydrothermal treatment | Journal of Biomedical Materials Research Part B | 1995 | 319 |
| 19 | KLF1 regulates BCL11A expression and γ- to β-globin gene switching | Nature Genetics | 2010 | 314 |
| 20 | Myeloperoxidase and Horseradish Peroxidase Catalyze Tyrosine Nitration in Proteins from Nitrite and Hydrogen Peroxide | Archives of Biochemistry and Biophysics | 1998 | 309 |
| 21 | The Microtubule-associated Protein Tau Is Extensively Modified with O-linked N-acetylglucosamine | Journal of Biological Chemistry | 1996 | 296 |
| 22 | Endolysins as Antimicrobials | Advances in Virus Research | 2012 | 291 |
| 23 | Regulation of cell cycle progression and gene expression by H2A deubiquitination | Nature | 2007 | 274 |
| 24 | Correction of sickle cell disease by homologous recombination in embryonic stem cells | Blood | 2006 | 255 |
| 25 | Mycobacterium tuberculosis WhiB3 Maintains Redox Homeostasis by Regulating Virulence Lipid Anabolism to Modulate Macrophage Response | PLoS Pathogens | 2009 | 253 |
| 26 | Knockout-Transgenic Mouse Model of Sickle Cell Disease | Science | 1997 | 252 |
| 27 | Recurrent Respiratory Papillomatosis: A Longitudinal Study Comparing Severity Associated With Human Papilloma Viral Types 6 and 11 and Other Risk Factors in a Large Pediatric Population | Laryngoscope | 2004 | 233 |
| 28 | Binding of Xanthine Oxidase to Vascular Endothelium | Journal of Biological Chemistry | 1999 | 231 |
| 29 | ATF4 is an oxidative stress–inducible, prodeath transcription factor in neurons in vitro and in vivo | Journal of Experimental Medicine | 2008 | 219 |
| 30 | Complete Relaxation and Conformational Exchange Matrix (CORCEMA) Analysis of Intermolecular Saturation Transfer Effects in Reversibly Forming Ligand–Receptor Complexes | Journal of Magnetic Resonance | 2002 | 218 |
| 31 | Structural models of human apolipoprotein A-I: a critical analysis and review | Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids | 2001 | 212 |
| 32 | p38-Dependent Phosphorylation of the mRNA Decay-Promoting Factor KSRP Controls the Stability of Select Myogenic Transcripts | Molecular Cell | 2005 | 212 |
| 33 | Atf4 Regulates Obesity, Glucose Homeostasis, and Energy Expenditure | Diabetes | 2009 | 206 |
| 34 | Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2) | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 202 |
| 35 | Structure and function of a membrane component SecDF that enhances protein export | Nature | 2011 | 202 |
| 36 | 17‐Beta Hydroxysteroid Dehydrogenase 13 Is a Hepatic Retinol Dehydrogenase Associated With Histological Features of Nonalcoholic Fatty Liver Disease | Hepatology | 2019 | 200 |
| 37 | Targeted disruption of the activating transcription factor 4 gene results in severe fetal anemia in mice | Blood | 2002 | 199 |
| 38 | Role of Erythroid Kruppel-like Factor in Human γ- to β-Globin Gene Switching | Journal of Biological Chemistry | 1995 | 197 |
| 39 | Mesenchymal stem cells as a vehicle for targeted delivery of CRAds to lung metastases of breast carcinoma | Breast Cancer Research and Treatment | 2007 | 194 |
| 40 | Atrial Natriuretic Peptide Inhibits Transforming Growth Factor β–Induced Smad Signaling and Myofibroblast Transformation in Mouse Cardiac Fibroblasts | Circulation Research | 2008 | 188 |
| 41 | Polycistronic Lentiviral Vector for “Hit and Run” Reprogramming of Adult Skin Fibroblasts to Induced Pluripotent Stem Cells | Stem Cells | 2009 | 186 |
| 42 | Selective Detection and Site-Analysis of O-GlcNAc-Modified Glycopeptides by β-Elimination and Tandem Electrospray Mass Spectrometry | Analytical Biochemistry | 1996 | 185 |
| 43 | Novel Oligosaccharide Side Chains of the Collagen-like Region of BclA, the Major Glycoprotein of the Bacillus anthracis Exosporium | Journal of Biological Chemistry | 2004 | 185 |
| 44 | DNA instability in postmitotic neurons | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 184 |
| 45 | Effect of physical crosslinking methods on collagen-fiber durability in proteolytic solutions | | 1996 | 183 |
| 46 | Induction of KLF4 in basal keratinocytes blocks the proliferation–differentiation switch and initiates squamous epithelial dysplasia | Oncogene | 2005 | 183 |
| 47 | Correction of a mouse model of sickle cell disease: lentiviral/antisickling β-globin gene transduction of unmobilized, purified hematopoietic stem cells | Blood | 2003 | 182 |
| 48 | Dynamic O-GlcNAcylation of the Small Heat Shock Protein αB-Crystallin† | Biochemistry | 1996 | 170 |
| 49 | The natural history of human papillomavirus infections of the mucosal epithelia | Apmis | 2010 | 169 |
| 50 | microRNAs are biomarkers of oncogenic human papillomavirus infections | Proceedings of the National Academy of Sciences of the United States of America | 2014 | 168 |
