| # | Title | Journal | Year | Citations |
|---|
| 1 | Antibody neutralization and escape by HIV-1 | Nature | 2003 | 2,233 |
| 2 | Overview of the immune response | Journal of Allergy and Clinical Immunology | 2010 | 1,318 |
| 3 | Th17: An Effector CD4 T Cell Lineage with Regulatory T Cell Ties | Immunity | 2006 | 1,272 |
| 4 | Glycosylation in health and disease | Nature Reviews Nephrology | 2019 | 1,166 |
| 5 | Toll-like receptor–mediated cytokine production is differentially regulated by glycogen synthase kinase 3 | Nature Immunology | 2005 | 999 |
| 6 | Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry | Nature Medicine | 1998 | 985 |
| 7 | Immunoglobulin A (IgA): Molecular and Cellular Interactions Involved in IgA Biosynthesis and Immune Response | Advances in Immunology | 1987 | 919 |
| 8 | Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trial | Gene Therapy | 2000 | 914 |
| 9 | Marginal Zone and B1 B Cells Unite in the Early Response against T-Independent Blood-Borne Particulate Antigens | Immunity | 2001 | 891 |
| 10 | The mucosal immune system: from fundamental concepts to vaccine development | Vaccine | 1992 | 856 |
| 11 | Case Definitions, Diagnostic Algorithms, and Priorities in Encephalitis: Consensus Statement of the International Encephalitis Consortium | Clinical Infectious Diseases | 2013 | 792 |
| 12 | Marginal-zone B cells | Nature Reviews Immunology | 2002 | 762 |
| 13 | Reading DNA at single-nucleotide resolution with a mutant MspA nanopore and phi29 DNA polymerase | Nature Biotechnology | 2012 | 744 |
| 14 | Virus taxonomy: the database of the International Committee on Taxonomy of Viruses (ICTV) | Nucleic Acids Research | 2018 | 733 |
| 15 | Sensitivity of Human Immunodeficiency Virus Type 1 to the Fusion Inhibitor T-20 Is Modulated by Coreceptor Specificity Defined by the V3 Loop of gp120 | Journal of Virology | 2000 | 714 |
| 16 | Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus | Immunity | 2018 | 661 |
| 17 | Controlled vaccine release in the gut-associated lymphoid tissues. I. Orally administered biodegradable microspheres target the peyer's patches | Journal of Controlled Release | 1990 | 631 |
| 18 | Envelope-Constrained Neutralization-Sensitive HIV-1 After Heterosexual Transmission | Science | 2004 | 572 |
| 19 | PI3 Kinase Signals BCR-Dependent Mature B Cell Survival | Cell | 2009 | 564 |
| 20 | The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection | Journal of Experimental Medicine | 2009 | 562 |
| 21 | Epitopes on protein antigens: Misconceptions and realities | Cell | 1990 | 550 |
| 22 | Regulatory T cells expressing interleukin 10 develop from Foxp3+ and Foxp3− precursor cells in the absence of interleukin 10 | Nature Immunology | 2007 | 534 |
| 23 | Disclosure of the mycobacterial outer membrane: Cryo-electron tomography and vitreous sections reveal the lipid bilayer structure | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 511 |
| 24 | T‐cell exhaustion: characteristics, causes and conversion | Immunology | 2010 | 506 |
| 25 | Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens | Nature Genetics | 2014 | 505 |
| 26 | Grape Exosome-like Nanoparticles Induce Intestinal Stem Cells and Protect Mice From DSS-Induced Colitis | Molecular Therapy | 2013 | 495 |
| 27 | Nanopore DNA sequencing with MspA | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 472 |
| 28 | A Vital Role for Interleukin-21 in the Control of a Chronic Viral Infection | Science | 2009 | 466 |
| 29 | Helper T cell subsets for immunoglobulin A responses: oral immunization with tetanus toxoid and cholera toxin as adjuvant selectively induces Th2 cells in mucosa associated tissues. | Journal of Experimental Medicine | 1993 | 463 |
| 30 | Efficient recovery of infectious vesicular stomatitis virus entirely from cDNA clones. | Proceedings of the National Academy of Sciences of the United States of America | 1995 | 463 |
| 31 | Extensive variation of human immunodeficiency virus type-1 in vivo | Nature | 1988 | 450 |
| 32 | Origin of the human malaria parasite Plasmodium falciparum in gorillas | Nature | 2010 | 445 |
| 33 | Nucleotide sequence of Mason-Pfizer monkey virus: An immunosuppressive D-type retrovirus | Cell | 1986 | 414 |
| 34 | Discovery of a New Capsular Serotype (6C) within Serogroup 6 of Streptococcus pneumoniae | Journal of Clinical Microbiology | 2007 | 404 |
| 35 | Pneumococcal Virulence Factors: Structure and Function | Microbiology and Molecular Biology Reviews | 2001 | 395 |
| 36 | Adipose Tissue Exosome-Like Vesicles Mediate Activation of Macrophage-Induced Insulin Resistance | Diabetes | 2009 | 395 |
| 37 | CD4+ T Cell Help Is Required for the Formation of a Cytolytic CD8+ T Cell Subset that Protects against Chronic Infection and Cancer | Immunity | 2019 | 393 |
| 38 | The complete sequence of the mucosal pathogen Ureaplasma urealyticum | Nature | 2000 | 383 |
| 39 | Autoreactivity by design: innate B and T lymphocytes | Nature Reviews Immunology | 2001 | 379 |
| 40 | A Conserved Tryptophan-Rich Motif in the Membrane-Proximal Region of the Human Immunodeficiency Virus Type 1 gp41 Ectodomain Is Important for Env-Mediated Fusion and Virus Infectivity | Journal of Virology | 1999 | 377 |
| 41 | Aberrantly glycosylated IgA1 in IgA nephropathy patients is recognized by IgG antibodies with restricted heterogeneity | Journal of Clinical Investigation | 2009 | 356 |
| 42 | Innate and adaptive immune responses regulated by glycogen synthase kinase-3 (GSK3) | Trends in Immunology | 2010 | 341 |
| 43 | B1 cells: similarities and differences with other B cell subsets | Current Opinion in Immunology | 2001 | 337 |
| 44 | Aminoglycoside antibiotics mediate context-dependent suppression of termination codons in a mammalian translation system | Rna | 2000 | 335 |
| 45 | Patients with IgA nephropathy have increased serum galactose-deficient IgA1 levels | Kidney International | 2007 | 334 |
| 46 | Influenza type A virus neuraminidase does not play a role in viral entry, replication, assembly, or budding | Journal of Virology | 1995 | 331 |
| 47 | Mucosal adjuvant effect of cholera toxin in mice results from induction of T helper 2 (Th2) cells and IL-4. | Journal of Immunology | 1995 | 325 |
| 48 | Mycoplasma pneumoniae and Chlamydia pneumoniae in Asthma | Chest | 2002 | 323 |
| 49 | Positive Selection from Newly Formed to Marginal Zone B Cells Depends on the Rate of Clonal Production, CD19, and btk | Immunity | 2000 | 322 |
| 50 | IgA nephropathy | Nature Reviews Disease Primers | 2016 | 322 |
