| # | Title | Journal | Year | Citations |
|---|
| 1 | Comparison of Central-Venous to Mixed-Venous Oxygen Saturation During Changes in Oxygen Supply/Demand | Chest | 1989 | 1,047 |
| 2 | Altered regulation of airway epithelial cell chloride channels in cystic fibrosis | Science | 1986 | 566 |
| 3 | Advantages of RGD peptides for directing cell association with biomaterials | Biomaterials | 2011 | 555 |
| 4 | Chloride conductance expressed by delta F508 and other mutant CFTRs in Xenopus oocytes | Science | 1991 | 507 |
| 5 | A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation | Nature Medicine | 2006 | 433 |
| 6 | Motoneuron Death Triggered by a Specific Pathway Downstream of Fas | Neuron | 2002 | 407 |
| 7 | CFTR Is a Conductance Regulator as well as a Chloride Channel | Physiological Reviews | 1999 | 394 |
| 8 | Extracellular ATP as a signaling molecule for epithelial cells | Biochimica Et Biophysica Acta - Biomembranes | 2003 | 393 |
| 9 | Stoichiometry of a Recombinant GABAAReceptor | Journal of Neuroscience | 1996 | 391 |
| 10 | Interactions between the Neuroendocrine and Immune Systems: Common Hormones and Receptors | Immunological Reviews | 1987 | 362 |
| 11 | Cloning, sequencing, and expression of human gonadotropin releasing hormone (GnRH) receptor | Biochemical and Biophysical Research Communications | 1992 | 346 |
| 12 | Regulation of plasma membrane recycling by CFTR | Science | 1992 | 344 |
| 13 | The concept of a critical oxygen delivery | Intensive Care Medicine | 1987 | 324 |
| 14 | Suppression of a CFTR premature stop mutation in a bronchial epithelial cell line | Nature Medicine | 1997 | 315 |
| 15 | Angiotensin II type-1 receptor subtype cDNAs: Differential tissue expression and hormonal regulation | Biochemical and Biophysical Research Communications | 1992 | 302 |
| 16 | Free Radicals, Mitochondria, and Oxidized Lipids | Circulation Research | 2006 | 301 |
| 17 | Efficacy of myonuclear addition may explain differential myofiber growth among resistance-trained young and older men and women | American Journal of Physiology - Endocrinology and Metabolism | 2006 | 300 |
| 18 | A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosis | Brain Research Reviews | 2004 | 274 |
| 19 | Increasing the pore sizes of bone-mimetic electrospun scaffolds comprised of polycaprolactone, collagen I and hydroxyapatite to enhance cell infiltration | Biomaterials | 2012 | 249 |
| 20 | Correction of lethal intestinal defect in a mouse model of cystic fibrosis by human CFTR | Science | 1994 | 239 |
| 21 | Gut and muscle tissue PO2 in endotoxemic dogs during shock and resuscitation | Journal of Applied Physiology | 1994 | 231 |
| 22 | DETECTION OF HORMONE RELEASE FROM INDIVIDUAL CELLS IN MIXED POPULATIONS USING A REVERSE HEMOLYTIC PLAQUE ASSAY | Endocrinology | 1983 | 226 |
| 23 | Cerebellotectal pathways in the macaque: Implications for collicular generation of saccades | Neuroscience | 1990 | 222 |
| 24 | Deficiency in the Inhibitory Serine-Phosphorylation of Glycogen Synthase Kinase-3 Increases Sensitivity to Mood Disturbances | Neuropsychopharmacology | 2010 | 211 |
| 25 | CD133 Is a Marker of Bioenergetic Stress in Human Glioma | PLoS ONE | 2008 | 208 |
| 26 | Age differences in knee extension power, contractile velocity, and fatigability | Journal of Applied Physiology | 2005 | 207 |
| 27 | Regulation of Hypertrophic and Apoptotic Signaling Pathways by Reactive Oxygen Species in Cardiac Myocytes | Antioxidants and Redox Signaling | 2003 | 200 |
| 28 | Astrocytic production of nerve growth factor in motor neuron apoptosis: implications for amyotrophic lateral sclerosis | Journal of Neurochemistry | 2004 | 200 |
| 29 | Differential gene expression profiling in human brain tumors | Physiological Genomics | 2001 | 195 |
| 30 | Production of immunoreactive growth hormone by mononuclear leukocytes | FASEB Journal | 1988 | 187 |
| 31 | Polarization-dependent apical membrane CFTR targeting underlies cAMP-stimulated Cl- secretion in epithelial cells | American Journal of Physiology - Cell Physiology | 1994 | 187 |
| 32 | Individual differences in diffuse noxious inhibitory controls (DNIC): association with clinical variables | Pain | 2003 | 187 |
| 33 | Protein hormones and immunity | Brain, Behavior, and Immunity | 2007 | 187 |
| 34 | Sialylation of the Fas Death Receptor by ST6Gal-I Provides Protection against Fas-mediated Apoptosis in Colon Carcinoma Cells | Journal of Biological Chemistry | 2011 | 180 |
| 35 | Expression and polarized targeting of a rab3 isoform in epithelial cells. | Journal of Cell Biology | 1994 | 178 |
| 36 | Cystic Fibrosis Transmembrane Conductance Regulator Facilitates ATP Release by Stimulating a Separate ATP Release Channel for Autocrine Control of Cell Volume Regulation | Journal of Biological Chemistry | 2001 | 176 |
| 37 | Estradiol-Induced Increase in the Magnitude of Long-Term Potentiation Is Prevented by Blocking NR2B-Containing Receptors | Journal of Neuroscience | 2006 | 169 |
| 38 | The immune system as the sixth sense | Journal of Internal Medicine | 2005 | 164 |
| 39 | Eye movements induced by pontine stimulation: interaction with visually triggered saccades | Journal of Neurophysiology | 1987 | 163 |
| 40 | Envelope glycoprotein gp120 of human immunodeficiency virus type 1 alters ion transport in astrocytes: implications for AIDS dementia complex. | Proceedings of the National Academy of Sciences of the United States of America | 1994 | 162 |
| 41 | Emerging Role of α2,6-Sialic Acid as a Negative Regulator of Galectin Binding and Function | Journal of Biological Chemistry | 2011 | 162 |
| 42 | Peroxynitrite triggers a phenotypic transformation in spinal cord astrocytes that induces motor neuron apoptosis | Journal of Neuroscience Research | 2002 | 161 |
| 43 | Aminoglycoside suppression of a premature stop mutation in a Cftr–/– mouse carrying a human CFTR-G542X transgene | Journal of Molecular Medicine | 2002 | 160 |
| 44 | The Cystic Fibrosis-causing Mutation ΔF508 Affects Multiple Steps in Cystic Fibrosis Transmembrane Conductance Regulator Biogenesis | Journal of Biological Chemistry | 2010 | 160 |
| 45 | Refractory Hypertension: Definition, Prevalence, and Patient Characteristics | Journal of Clinical Hypertension | 2012 | 160 |
| 46 | A nitric oxide releasing, self assembled peptide amphiphile matrix that mimics native endothelium for coating implantable cardiovascular devices | Biomaterials | 2010 | 159 |
| 47 | A Pharmacologic Approach to Acquired Cystic Fibrosis Transmembrane Conductance Regulator Dysfunction in Smoking Related Lung Disease | PLoS ONE | 2012 | 159 |
| 48 | Functional domains within the degenerin/epithelial sodium channel (Deg/ENaC) superfamily of ion channels | Journal of Physiology | 1999 | 154 |
| 49 | Variant glycosylation: an underappreciated regulatory mechanism for β1 integrins | Biochimica Et Biophysica Acta - Biomembranes | 2004 | 152 |
| 50 | A switch between two modes of synaptic transmission mediated by presynaptic inhibition | Nature | 1995 | 147 |
