| # | Title | Journal | Year | Citations |
|---|
| 1 | Genetic Restriction of HIV-1 Infection and Progression to AIDS by a Deletion Allele of the CKR5 Structural Gene | Science | 1996 | 2,365 |
| 2 | Mixed linear model approach adapted for genome-wide association studies | Nature Genetics | 2010 | 2,022 |
| 3 | Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer | Cell | 2017 | 1,742 |
| 4 | Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017 | JAMA Oncology | 2019 | 1,691 |
| 5 | Global Burden of Hypertension and Systolic Blood Pressure of at Least 110 to 115 mm Hg, 1990-2015 | JAMA - Journal of the American Medical Association | 2017 | 1,492 |
| 6 | The Recent Prevalence of Osteoporosis and Low Bone Mass in the United States Based on Bone Mineral Density at the Femoral Neck or Lumbar Spine | Journal of Bone and Mineral Research | 2014 | 1,305 |
| 7 | Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2016 | JAMA Oncology | 2018 | 1,260 |
| 8 | Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program | Nature | 2021 | 1,069 |
| 9 | The Reasons for Geographic and Racial Differences in Stroke Study: Objectives and Design | Neuroepidemiology | 2005 | 948 |
| 10 | Influence of combinations of human major histocompatibility complex genes on the course of HIV–1 infection | Nature Medicine | 1996 | 911 |
| 11 | Effect of Intensive vs Standard Blood Pressure Control on Probable Dementia | JAMA - Journal of the American Medical Association | 2019 | 786 |
| 12 | Alpha-2 macroglobulin is genetically associated with Alzheimer disease | Nature Genetics | 1998 | 680 |
| 13 | Potential US Population Impact of the 2017 ACC/AHA High Blood Pressure Guideline | Circulation | 2018 | 656 |
| 14 | Metabolic Syndrome Prevalence by Race/Ethnicity and Sex in the United States, National Health and Nutrition Examination Survey, 1988–2012 | Preventing Chronic Disease | 2017 | 633 |
| 15 | Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction | Nature | 2015 | 581 |
| 16 | Trends in Blood Pressure Control Among US Adults With Hypertension, 1999-2000 to 2017-2018 | JAMA - Journal of the American Medical Association | 2020 | 498 |
| 17 | Validation of the Atherosclerotic Cardiovascular Disease Pooled Cohort Risk Equations | JAMA - Journal of the American Medical Association | 2014 | 474 |
| 18 | Incidence and outcomes of neonatal acute kidney injury (AWAKEN): a multicentre, multinational, observational cohort study | The Lancet Child and Adolescent Health | 2017 | 453 |
| 19 | γ-Glutamyltransferase Is a Predictor of Incident Diabetes and Hypertension: The Coronary Artery Risk Development in Young Adults (CARDIA) Study | Clinical Chemistry | 2003 | 409 |
| 20 | Effectiveness of mRNA-1273 against SARS-CoV-2 Omicron and Delta variants | Nature Medicine | 2022 | 398 |
| 21 | The Relationship Between Visit-to-Visit Variability in Systolic Blood Pressure and All-Cause Mortality in the General Population | Hypertension | 2011 | 397 |
| 22 | Disparities in stroke incidence contributing to disparities in stroke mortality | Annals of Neurology | 2011 | 379 |
| 23 | Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases | JAMA Oncology | 2017 | 376 |
| 24 | Inherited causes of clonal haematopoiesis in 97,691 whole genomes | Nature | 2020 | 376 |
| 25 | Incidence Rates of Salivary Gland Tumors: Results from a Population-Based Study | Otolaryngology - Head and Neck Surgery | 1999 | 375 |
| 26 | Atrial Fibrillation and the Risk of Myocardial Infarction | JAMA Internal Medicine | 2014 | 362 |
| 27 | The non-Hodgkin lymphomas: A review of the epidemiologic literature | International Journal of Cancer | 2007 | 359 |
| 28 | Genome-Wide Association Study of Plasma Polyunsaturated Fatty Acids in the InCHIANTI Study | PLoS Genetics | 2009 | 351 |
| 29 | Global stroke statistics | International Journal of Stroke | 2017 | 351 |
| 30 | Plasma homocyst(e)ine, folate, and vitamin B-12 concentrations and risk for early-onset coronary artery disease | American Journal of Clinical Nutrition | 1994 | 350 |
| 31 | Global Stroke Statistics | International Journal of Stroke | 2014 | 329 |
| 32 | Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders | American Journal of Human Genetics | 2018 | 326 |
| 33 | Genetic Loci Associated with Plasma Phospholipid n-3 Fatty Acids: A Meta-Analysis of Genome-Wide Association Studies from the CHARGE Consortium | PLoS Genetics | 2011 | 324 |
| 34 | Meta-analysis of Correlated Traits via Summary Statistics from GWASs with an Application in Hypertension | American Journal of Human Genetics | 2015 | 321 |
| 35 | Hypertension Awareness, Treatment, and Control in Adults With CKD: Results From the Chronic Renal Insufficiency Cohort (CRIC) Study | American Journal of Kidney Diseases | 2010 | 320 |
| 36 | Prevalence of polycystic ovary syndrome (PCOS) in first-degree relatives of patients with PCOS | Fertility and Sterility | 2001 | 315 |
| 37 | Systemic lupus erythematosus in three ethnic groups. XII. Risk factors for lupus nephritis after diagnosis | Lupus | 2002 | 315 |
| 38 | Position paper Statin intolerance – an attempt at a unified definition. Position paper from an International Lipid Expert Panel | Archives of Medical Science | 2015 | 311 |
| 39 | The maximum standardized uptake values on positron emission tomography of a non-small cell lung cancer predict stage, recurrence, and survival | Journal of Thoracic and Cardiovascular Surgery | 2005 | 301 |
| 40 | Systemic lupus erythematosus in three ethnic groups. VIII. Predictors of early mortality in the LUMINA cohort | Arthritis and Rheumatism | 2001 | 299 |
| 41 | Abundant Lipid and Protein Components of Drusen | PLoS ONE | 2010 | 293 |
| 42 | Prevention and Control of Hypertension | Journal of the American College of Cardiology | 2018 | 290 |
| 43 | A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study | BMC Medical Genetics | 2007 | 289 |
| 44 | Association of Intensive vs Standard Blood Pressure Control With Cerebral White Matter Lesions | JAMA - Journal of the American Medical Association | 2019 | 285 |
| 45 | Potential U.S. Population Impact of the 2017 ACC/AHA High Blood Pressure Guideline | Journal of the American College of Cardiology | 2018 | 283 |
| 46 | A DNA methylation biomarker of alcohol consumption | Molecular Psychiatry | 2018 | 280 |
| 47 | Aspirin and reduced risk of esophageal carcinoma | Cancer | 1995 | 272 |
| 48 | Acute Kidney Injury Reduces Survival in Very Low Birth Weight Infants | Pediatric Research | 2011 | 272 |
| 49 | Predictors of Nonadherence to Statins: A Systematic Review and Meta-Analysis | Annals of Pharmacotherapy | 2010 | 267 |
| 50 | Aging and dark adaptation | Vision Research | 1999 | 266 |
