| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Tumor Exosomes Inhibit Differentiation of Bone Marrow Dendritic Cells | Journal of Immunology | 2007 | 373 |
| 3 | Regulation of EMT in Colorectal Cancer: A Culprit in Metastasis | Cancers | 2017 | 365 |
| 4 | Virologic and Immunologic Determinants of Heterosexual Transmission of Human Immunodeficiency Virus Type 1 in Africa | AIDS Research and Human Retroviruses | 2001 | 338 |
| 5 | Derivation and external validation of the PLASMIC score for rapid assessment of adults with thrombotic microangiopathies: a cohort study | Lancet Haematology,the | 2017 | 338 |
| 6 | Profiling the Specificity of Neutralizing Antibodies in a Large Panel of Plasmas from Patients Chronically Infected with Human Immunodeficiency Virus Type 1 Subtypes B and C | Journal of Virology | 2008 | 337 |
| 7 | Acute myeloid leukemia transforms the bone marrow niche into a leukemia-permissive microenvironment through exosome secretion | Leukemia | 2018 | 304 |
| 8 | Phase 3 trial of defibrotide for the treatment of severe veno-occlusive disease and multi-organ failure | Blood | 2016 | 255 |
| 9 | Talimogene laherparepvec: First in class oncolytic virotherapy | Human Vaccines and Immunotherapeutics | 2018 | 247 |
| 10 | Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemia | Nature Communications | 2016 | 218 |
| 11 | Brentuximab vedotin plus bendamustine: a highly active first salvage regimen for relapsed or refractory Hodgkin lymphoma | Blood | 2018 | 199 |
| 12 | Regions of the JAK2 Tyrosine Kinase Required for Coupling to the Growth Hormone Receptor | Journal of Biological Chemistry | 1995 | 152 |
| 13 | Warfarin Dosing in Patients With Impaired Kidney Function | American Journal of Kidney Diseases | 2010 | 147 |
| 14 | Palmitoylation-dependent activation of MC1R prevents melanomagenesis | Nature | 2017 | 143 |
| 15 | Treatment of relapsed and refractory multiple myeloma: recommendations from the International Myeloma Working Group | Lancet Oncology, The | 2021 | 136 |
| 16 | TopBP1 recruits Brg1/Brm to repress E2F1-induced apoptosis, a novel pRb-independent and E2F1-specific control for cell survival | Genes and Development | 2004 | 135 |
| 17 | Regulation of E2F1 by BRCT Domain-Containing Protein TopBP1 | Molecular and Cellular Biology | 2003 | 131 |
| 18 | Combined targeting of BCL-2 and BCR-ABL tyrosine kinase eradicates chronic myeloid leukemia stem cells | Science Translational Medicine | 2016 | 130 |
| 19 | First Clinical Study of the B-Cell Maturation Antigen (BCMA) 2+1 T Cell Engager (TCE) CC-93269 in Patients (Pts) with Relapsed/Refractory Multiple Myeloma (RRMM): Interim Results of a Phase 1 Multicenter Trial | Blood | 2019 | 127 |
| 20 | Resource Use and Medicare Costs During Lay Navigation for Geriatric Patients With Cancer | JAMA Oncology | 2017 | 126 |
| 21 | Association of Event-Free and Distant Recurrence–Free Survival With Individual-Level Pathologic Complete Response in Neoadjuvant Treatment of Stages 2 and 3 Breast Cancer | JAMA Oncology | 2020 | 119 |
| 22 | Safety of Polysorbate 80 in the Oncology Setting | Advances in Therapy | 2018 | 114 |
| 23 | Safety, Tolerance, and Efficacy of Posaconazole Therapy in Patients with Nonmeningeal Disseminated or Chronic Pulmonary Coccidioidomycosis | Clinical Infectious Diseases | 2007 | 110 |
| 24 | Pretreatment with Dexamethasone Increases Antitumor Activity of Carboplatin and Gemcitabine in Mice Bearing Human Cancer Xenografts | Clinical Cancer Research | 2004 | 105 |
| 25 | MIR106B and MIR93 Prevent Removal of Bacteria From Epithelial Cells by Disrupting ATG16L1-Mediated Autophagy | Gastroenterology | 2014 | 98 |
| 26 | Myristoylation confers noncanonical AMPK functions in autophagy selectivity and mitochondrial surveillance | Nature Communications | 2015 | 98 |
| 27 | Myelodysplastic syndrome unrelated to lentiviral vector in a patient treated with gene therapy for sickle cell disease | Blood Advances | 2020 | 93 |
| 28 | A phase 1b study of AFM13 in combination with pembrolizumab in patients with relapsed or refractory Hodgkin lymphoma | Blood | 2020 | 92 |
| 29 | Regulation of TopBP1 oligomerization by Akt/PKB for cell survival | EMBO Journal | 2006 | 87 |
| 30 | Parsaclisib, a potent and highly selective PI3Kδ inhibitor, in patients with relapsed or refractory B-cell malignancies | Blood | 2019 | 84 |
| 31 | Comparing and Validating Machine Learning Models for Mycobacterium tuberculosis Drug Discovery | Molecular Pharmaceutics | 2018 | 83 |
| 32 | The coxsackievirus and adenovirus receptor acts as a tumour suppressor in malignant glioma cells | British Journal of Cancer | 2003 | 80 |
| 33 | MCPH1/BRIT1 cooperates with E2F1 in the activation of checkpoint, DNA repair and apoptosis | EMBO Reports | 2008 | 80 |
| 34 | Implementation and Impact of Patient Lay Navigator-Led Advance Care Planning Conversations | Journal of Pain and Symptom Management | 2017 | 79 |
| 35 | A Role for 14-3-3τ in E2F1 Stabilization and DNA Damage-induced Apoptosis | Journal of Biological Chemistry | 2004 | 77 |
| 36 | γδ T cells: A new frontier for immunotherapy? | Biology of Blood and Marrow Transplantation | 2005 | 75 |
| 37 | Phase 1 Trial of ALRN-6924, a Dual Inhibitor of MDMX and MDM2, in Patients with Solid Tumors and Lymphomas Bearing Wild-type TP53 | Clinical Cancer Research | 2021 | 74 |
| 38 | Metformin impairs the growth of liver kinase B1-intact cervical cancer cells | Gynecologic Oncology | 2012 | 72 |
| 39 | Resectability of Pancreatic Adenocarcinoma in Patients with Locally Advanced Disease Downstaged by Preoperative Therapy: A Challenge for MDCT | American Journal of Roentgenology | 2010 | 71 |
| 40 | Piperlongumine induces autophagy by targeting p38 signaling | Cell Death and Disease | 2013 | 71 |
| 41 | Tumor-intrinsic and -extrinsic determinants of response to blinatumomab in adults with B-ALL | Blood | 2021 | 70 |
| 42 | Effect of Cigarette Smoking on Epithelial to Mesenchymal Transition (EMT) in Lung Cancer | Journal of Clinical Medicine | 2016 | 69 |
| 43 | STRAP Promotes Stemness of Human Colorectal Cancer via Epigenetic Regulation of the NOTCH Pathway | Cancer Research | 2017 | 69 |
| 44 | International harmonization in performing and reporting minimal residual disease assessment in multiple myeloma trials | Leukemia | 2021 | 69 |
| 45 | Using a Tropism-Modified Adenoviral Vector to Circumvent Inhibitory Factors in Ascites Fluid | Human Gene Therapy | 2000 | 68 |
| 46 | SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function | Cell Stem Cell | 2018 | 68 |
| 47 | A randomized, controlled phase III trial of nab-Paclitaxel versus dacarbazine in chemotherapy-naïve patients with metastatic melanoma | Annals of Oncology | 2015 | 67 |
| 48 | ATM-Mediated Stabilization of hMutL DNA Mismatch Repair Proteins Augments p53 Activation during DNA Damage | Molecular and Cellular Biology | 2004 | 66 |
| 49 | Docetaxel or pemetrexed with or without cetuximab in recurrent or progressive non-small-cell lung cancer after platinum-based therapy: a phase 3, open-label, randomised trial | Lancet Oncology, The | 2013 | 66 |
| 50 | Disparities in Utilization of Autologous Hematopoietic Cell Transplantation for Treatment of Multiple Myeloma | Biology of Blood and Marrow Transplantation | 2015 | 66 |
