| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | UALCAN: A Portal for Facilitating Tumor Subgroup Gene Expression and Survival Analyses | Neoplasia | 2017 | 4,166 |
| 3 | Interleukin 17–producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages | Nature Immunology | 2005 | 4,106 |
| 4 | Transforming growth factor-β induces development of the TH17 lineage | Nature | 2006 | 3,086 |
| 5 | Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing | Nature Genetics | 2019 | 1,962 |
| 6 | The Tumor Microenvironment Innately Modulates Cancer Progression | Cancer Research | 2019 | 1,781 |
| 7 | Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease | Nature Genetics | 2011 | 1,676 |
| 8 | IL-17 Family Cytokines and the Expanding Diversity of Effector T Cell Lineages | Annual Review of Immunology | 2007 | 1,672 |
| 9 | Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation | Nature Medicine | 2003 | 1,606 |
| 10 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 11 | Reciprocal interactions of the intestinal microbiota and immune system | Nature | 2012 | 1,278 |
| 12 | Th17: An Effector CD4 T Cell Lineage with Regulatory T Cell Ties | Immunity | 2006 | 1,272 |
| 13 | A Novel Nanoparticle Drug Delivery System: The Anti-inflammatory Activity of Curcumin Is Enhanced When Encapsulated in Exosomes | Molecular Therapy | 2010 | 1,267 |
| 14 | Cell-Surface Calreticulin Initiates Clearance of Viable or Apoptotic Cells through trans-Activation of LRP on the Phagocyte | Cell | 2005 | 1,225 |
| 15 | The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic Neoplasms | Leukemia | 2022 | 1,211 |
| 16 | TGF-β and BMP signaling in osteoblast, skeletal development, and bone formation, homeostasis and disease | Bone Research | 2016 | 1,099 |
| 17 | Thrombospondin-1 Is a Major Activator of TGF-β1 In Vivo | Cell | 1998 | 1,094 |
| 18 | Treatment of Brain Inflammatory Diseases by Delivering Exosome Encapsulated Anti-inflammatory Drugs From the Nasal Region to the Brain | Molecular Therapy | 2011 | 1,070 |
| 19 | Mycoplasma pneumoniaeand Its Role as a Human Pathogen | Clinical Microbiology Reviews | 2004 | 1,069 |
| 20 | Eosinophilic esophagitis attributed to gastroesophageal reflux: Improvement with an amino acid-based formula | Gastroenterology | 1995 | 1,028 |
| 21 | The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms | Leukemia | 2022 | 1,023 |
| 22 | TGF-β1–induced migration of bone mesenchymal stem cells couples bone resorption with formation | Nature Medicine | 2009 | 1,001 |
| 23 | Late Developmental Plasticity in the T Helper 17 Lineage | Immunity | 2009 | 934 |
| 24 | Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trial | Gene Therapy | 2000 | 914 |
| 25 | Disorders of Bone Remodeling | Annual Review of Pathology: Mechanisms of Disease | 2011 | 904 |
| 26 | Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease | Nature Genetics | 2017 | 783 |
| 27 | UALCAN: An update to the integrated cancer data analysis platform | Neoplasia | 2022 | 666 |
| 28 | Th17 cells transdifferentiate into regulatory T cells during resolution of inflammation | Nature | 2015 | 653 |
| 29 | Insulin Receptor Signaling in Osteoblasts Regulates Postnatal Bone Acquisition and Body Composition | Cell | 2010 | 651 |
| 30 | The hypoxia-inducible factor α pathway couples angiogenesis to osteogenesis during skeletal development | Journal of Clinical Investigation | 2007 | 616 |
| 31 | Intracellular cyclic GMP receptor proteins | FASEB Journal | 1993 | 612 |
| 32 | Amniotic Infection Syndrome: Nosology and Reproducibility of Placental Reaction Patterns | Pediatric and Developmental Pathology | 2003 | 574 |
| 33 | Autoimmune hemolytic anemia | American Journal of Hematology | 2002 | 564 |
| 34 | Pneumococcal Capsules and Their Types: Past, Present, and Future | Clinical Microbiology Reviews | 2015 | 557 |
| 35 | Activation of latent TGF-β by thrombospondin-1: mechanisms and physiology | Cytokine and Growth Factor Reviews | 2000 | 537 |
| 36 | Expanding the effector CD4 T-cell repertoire: the Th17 lineage | Current Opinion in Immunology | 2006 | 535 |
| 37 | Regulatory T cells expressing interleukin 10 develop from Foxp3+ and Foxp3− precursor cells in the absence of interleukin 10 | Nature Immunology | 2007 | 534 |
| 38 | Cellular mechanisms of redox cell signalling: role of cysteine modification in controlling antioxidant defences in response to electrophilic lipid oxidation products | Biochemical Journal | 2004 | 531 |
| 39 | Essential Role of β-Catenin in Postnatal Bone Acquisition | Journal of Biological Chemistry | 2005 | 530 |
| 40 | The AP-1 transcription factor Batf controls TH17 differentiation | Nature | 2009 | 524 |
| 41 | Proteoglycans in cancer biology, tumour microenvironment and angiogenesis | Journal of Cellular and Molecular Medicine | 2011 | 484 |
| 42 | Induction of myeloid‐derived suppressor cells by tumor exosomes | International Journal of Cancer | 2009 | 483 |
| 43 | Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity | Nature Communications | 2020 | 480 |
| 44 | Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions | Nature Genetics | 2010 | 479 |
| 45 | Invited Review: cGMP-dependent protein kinase signaling mechanisms in smooth muscle: from the regulation of tone to gene expression | Journal of Applied Physiology | 2001 | 452 |
| 46 | Experimental models of inflammatory bowel disease reveal innate, adaptive, and regulatory mechanisms of host dialogue with the microbiota | Immunological Reviews | 2005 | 449 |
| 47 | Hypoxia, red blood cells, and nitrite regulate NO-dependent hypoxic vasodilation | Blood | 2006 | 444 |
| 48 | Activation of the hypoxia-inducible factor-1α pathway accelerates bone regeneration | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 442 |
| 49 | Guidelines on the use of therapeutic apheresis in clinical practice—Evidence‐based approach from the apheresis applications committee of the American Society for Apheresis | Journal of Clinical Apheresis | 2010 | 441 |
| 50 | The de-adhesive activity of matricellular proteins: is intermediate cell adhesion an adaptive state? | Journal of Clinical Investigation | 2001 | 412 |
