| # | Title | Journal | Year | Citations |
|---|
| 1 | Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent | Analytical Biochemistry | 1968 | 6,535 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 3 | EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update | Annals of the Rheumatic Diseases | 2017 | 3,366 |
| 4 | Clinical Practice Guidelines for the Management Candidiasis: 2009 Update by the Infectious Diseases Society of America | Clinical Infectious Diseases | 2009 | 2,644 |
| 5 | Antibody neutralization and escape by HIV-1 | Nature | 2003 | 2,233 |
| 6 | Genetics of rheumatoid arthritis contributes to biology and drug discovery | Nature | 2014 | 1,974 |
| 7 | EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2019 update | Annals of the Rheumatic Diseases | 2020 | 1,860 |
| 8 | Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017 | JAMA Oncology | 2019 | 1,691 |
| 9 | Emergence of Resistant Human Immunodeficiency Virus Type 1 in Patients Receiving Fusion Inhibitor (T-20) Monotherapy | Antimicrobial Agents and Chemotherapy | 2002 | 1,483 |
| 10 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 11 | Revision and Update of the Consensus Definitions of Invasive Fungal Disease From the European Organization for Research and Treatment of Cancer and the Mycoses Study Group Education and Research Consortium | Clinical Infectious Diseases | 2020 | 1,429 |
| 12 | The Biological Basis for Cardiac Repair After Myocardial Infarction | Circulation Research | 2016 | 1,408 |
| 13 | Origin of HIV-1 in the chimpanzee Pan troglodytes troglodytes | Nature | 1999 | 1,405 |
| 14 | Benefits of Modest Weight Loss in Improving Cardiovascular Risk Factors in Overweight and Obese Individuals With Type 2 Diabetes | Diabetes Care | 2011 | 1,342 |
| 15 | Structure and function of immunoglobulins | Journal of Allergy and Clinical Immunology | 2010 | 1,322 |
| 16 | High levels of HIV-1 in plasma during all stages of infection determined by competitive PCR | Science | 1993 | 1,290 |
| 17 | Reciprocal interactions of the intestinal microbiota and immune system | Nature | 2012 | 1,278 |
| 18 | A Novel Nanoparticle Drug Delivery System: The Anti-inflammatory Activity of Curcumin Is Enhanced When Encapsulated in Exosomes | Molecular Therapy | 2010 | 1,267 |
| 19 | Glycosylation in health and disease | Nature Reviews Nephrology | 2019 | 1,166 |
| 20 | Antiviral pressure exerted by HIV-l-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus | Nature Medicine | 1997 | 1,138 |
| 21 | Experimental models of inflammatory bowel disease | Gastroenterology | 1995 | 1,124 |
| 22 | Treatment of Brain Inflammatory Diseases by Delivering Exosome Encapsulated Anti-inflammatory Drugs From the Nasal Region to the Brain | Molecular Therapy | 2011 | 1,070 |
| 23 | Recent Developments in Myofibroblast Biology | American Journal of Pathology | 2012 | 1,043 |
| 24 | In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors | Nature | 1995 | 1,023 |
| 25 | AIDS as a Zoonosis: Scientific and Public Health Implications | Science | 2000 | 1,012 |
| 26 | Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry | Nature Medicine | 1998 | 985 |
| 27 | Characteristics associated with hospitalisation for COVID-19 in people with rheumatic disease: data from the COVID-19 Global Rheumatology Alliance physician-reported registry | Annals of the Rheumatic Diseases | 2020 | 908 |
| 28 | A revised airway epithelial hierarchy includes CFTR-expressing ionocytes | Nature | 2018 | 878 |
| 29 | The mucosal immune system: from fundamental concepts to vaccine development | Vaccine | 1992 | 856 |
| 30 | miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis | Journal of Experimental Medicine | 2010 | 822 |
| 31 | Timing of renal replacement therapy and clinical outcomes in critically ill patients with severe acute kidney injury | Journal of Critical Care | 2009 | 820 |
| 32 | The ABCs of solute carriers: physiological, pathological and therapeutic implications of human membrane transport proteins | Pflugers Archiv European Journal of Physiology | 2004 | 817 |
| 33 | Case Definitions, Diagnostic Algorithms, and Priorities in Encephalitis: Consensus Statement of the International Encephalitis Consortium | Clinical Infectious Diseases | 2013 | 792 |
| 34 | Effect of Intensive vs Standard Blood Pressure Control on Probable Dementia | JAMA - Journal of the American Medical Association | 2019 | 786 |
| 35 | Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry | Nature Immunology | 2019 | 760 |
| 36 | Insights From the NHLBI-Sponsored Women’s Ischemia Syndrome Evaluation (WISE) Study | Journal of the American College of Cardiology | 2006 | 727 |
| 37 | Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function | Nature Genetics | 2005 | 695 |
| 38 | Interleukin-1 Receptor Blockade Is Associated With Reduced Mortality in Sepsis Patients With Features of Macrophage Activation Syndrome | Critical Care Medicine | 2016 | 659 |
| 39 | Interleukin 17–producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice | Nature Immunology | 2008 | 639 |
| 40 | Innate lymphoid cells regulate CD4+ T-cell responses to intestinal commensal bacteria | Nature | 2013 | 639 |
| 41 | Increasing arteriovenous fistulas in hemodialysis patients: Problems and solutions | Kidney International | 2002 | 636 |
| 42 | Major expansion of CD8+ T cells with a predominant Vβ usage during the primary immune response to HIV | Nature | 1994 | 630 |
| 43 | A novel polymorphism of FcgammaRIIIa (CD16) alters receptor function and predisposes to autoimmune disease. | Journal of Clinical Investigation | 1997 | 627 |
| 44 | Insights From the NHLBI-Sponsored Women’s Ischemia Syndrome Evaluation (WISE) Study | Journal of the American College of Cardiology | 2006 | 620 |
| 45 | Elective Stenting of the Extracranial Carotid Arteries | Circulation | 1997 | 617 |
| 46 | Estimated glomerular filtration rate and albuminuria for prediction of cardiovascular outcomes: a collaborative meta-analysis of individual participant data | Lancet Diabetes and Endocrinology,the | 2015 | 604 |
| 47 | New insights into the mechanisms of polyphenols beyond antioxidant properties; lessons from the green tea polyphenol, epigallocatechin 3-gallate | Redox Biology | 2014 | 603 |
| 48 | Smoking and Mortality — Beyond Established Causes | New England Journal of Medicine | 2015 | 587 |
| 49 | Thematic review series: The Pathogenesis of Atherosclerosis The oxidation hypothesis of atherogenesis: the role of oxidized phospholipids and HDL | Journal of Lipid Research | 2004 | 585 |
| 50 | Behavioral vs Drug Treatment for Urge Urinary Incontinence in Older Women | JAMA - Journal of the American Medical Association | 1998 | 578 |
