| # | Title | Journal | Year | Citations |
|---|
| 1 | The multiMiR R package and database: integration of microRNA–target interactions along with their disease and drug associations | Nucleic Acids Research | 2014 | 409 |
| 2 | Multitargeted therapy of cancer by silymarin | Cancer Letters | 2008 | 349 |
| 3 | A phase I and pharmacokinetic study of silybin-phytosome in prostate cancer patients | Investigational New Drugs | 2006 | 259 |
| 4 | Antimetastatic efficacy of silibinin: molecular mechanisms and therapeutic potential against cancer | Cancer and Metastasis Reviews | 2010 | 212 |
| 5 | Clinical and economic outcomes of involving pharmacists in the direct care of critically ill patients with infections* | Critical Care Medicine | 2008 | 203 |
| 6 | Gallic Acid, an Active Constituent of Grape Seed Extract, Exhibits Anti-proliferative, Pro-apoptotic and Anti-tumorigenic Effects Against Prostate Carcinoma Xenograft Growth in Nude Mice | Pharmaceutical Research | 2009 | 197 |
| 7 | The Effect of Lopinavir/Ritonavir on the Renal Clearance of Tenofovir in HIV-infected Patients | Clinical Pharmacology and Therapeutics | 2008 | 188 |
| 8 | Anticancer and Cancer Chemopreventive Potential of Grape Seed Extract and Other Grape-Based Products | Journal of Nutrition | 2009 | 188 |
| 9 | Silicone Oil Microdroplets and Protein Aggregates in Repackaged Bevacizumab and Ranibizumab: Effects of Long-term Storage and Product Mishandling | | 2011 | 166 |
| 10 | Grape Seed Extract Inhibits In vitro and In vivo Growth of Human Colorectal Carcinoma Cells | Clinical Cancer Research | 2006 | 155 |
| 11 | Natural products and colon cancer: current status and future prospects | Drug Development Research | 2008 | 149 |
| 12 | The human sirtuin family: Evolutionary divergences and functions | Human Genomics | 2011 | 148 |
| 13 | Silibinin Inhibits Colorectal Cancer Growth by Inhibiting Tumor Cell Proliferation and Angiogenesis | Cancer Research | 2008 | 147 |
| 14 | Silibinin Inhibits Established Prostate Tumor Growth, Progression, Invasion, and Metastasis and Suppresses Tumor Angiogenesis and Epithelial-Mesenchymal Transition in Transgenic Adenocarcinoma of the Mouse Prostate Model Mice | Clinical Cancer Research | 2008 | 146 |
| 15 | Clinical and Genetic Determinants of Intracellular Tenofovir Diphosphate Concentrations in HIV-Infected Patients | Journal of Acquired Immune Deficiency Syndromes (1999) | 2008 | 143 |
| 16 | Genetic Disruption of the Multifunctional CD98/LAT1 Complex Demonstrates the Key Role of Essential Amino Acid Transport in the Control of mTORC1 and Tumor Growth | Cancer Research | 2016 | 143 |
| 17 | The Cost Effectiveness of Anticoagulation Management Services for Patients with Atrial Fibrillation and at High Risk of Stroke in the US | Pharmacoeconomics | 2006 | 132 |
| 18 | Mechanisms and preclinical efficacy of silibinin in preventing skin cancer | European Journal of Cancer | 2005 | 131 |
| 19 | The glutamine transporter ASCT2 (SLC1A5) promotes tumor growth independently of the amino acid transporter LAT1 (SLC7A5) | Journal of Biological Chemistry | 2018 | 131 |
| 20 | Prostate cancer chemoprevention by silibinin: Bench to bedside | Molecular Carcinogenesis | 2006 | 126 |
| 21 | Cytochrome P450 2C8 pharmacogenetics: a review of clinical studies | Pharmacogenomics | 2009 | 122 |
| 22 | Factors Related to Adherence to Statin Therapy | Annals of Pharmacotherapy | 2007 | 114 |
| 23 | A Potential Role for Cyclized Quinones Derived from Dopamine, DOPA, and 3,4-Dihydroxyphenylacetic Acid in Proteasomal Inhibition | Molecular Pharmacology | 2006 | 108 |
| 24 | Medulloblastoma Exosome Proteomics Yield Functional Roles for Extracellular Vesicles | PLoS ONE | 2012 | 108 |
| 25 | 4-Hydroxynonenal Inhibits SIRT3 via Thiol-Specific Modification | Chemical Research in Toxicology | 2011 | 107 |
| 26 | Growth Inhibition and Regression of Lung Tumors by Silibinin: Modulation of Angiogenesis by Macrophage-Associated Cytokines and Nuclear Factor-κB and Signal Transducers and Activators of Transcription 3 | Cancer Prevention Research | 2009 | 105 |
| 27 | Acrolein Inhibits Cytokine Gene Expression by Alkylating Cysteine and Arginine Residues in the NF-κB1 DNA Binding Domain | Journal of Biological Chemistry | 2007 | 103 |
| 28 | Exploring the Biology of Lipid Peroxidation-Derived Protein Carbonylation | Chemical Research in Toxicology | 2011 | 102 |
| 29 | Sulfonylurea pharmacogenomics in Type 2 diabetes: the influence of drug target and diabetes risk polymorphisms | Expert Review of Cardiovascular Therapy | 2010 | 97 |
| 30 | Determination of nucleoside analog mono-, di-, and tri-phosphates in cellular matrix by solid phase extraction and ultra-sensitive LC–MS/MS detection | Journal of Pharmaceutical and Biomedical Analysis | 2011 | 97 |
| 31 | Stage-Specific Inhibitory Effects and Associated Mechanisms of Silibinin on Tumor Progression and Metastasis in Transgenic Adenocarcinoma of the Mouse Prostate Model | Cancer Research | 2008 | 96 |
| 32 | Cytotoxic and Anti-oxidant Activities of Lanostane-Type Triterpenes Isolated from Poria cocos | Chemical and Pharmaceutical Bulletin | 2008 | 93 |
| 33 | Silibinin Suppresses Growth of Human Prostate Carcinoma PC-3 Orthotopic Xenograft via Activation of Extracellular Signal-Regulated Kinase 1/2 and Inhibition of Signal Transducers and Activators of Transcription Signaling | Clinical Cancer Research | 2009 | 93 |
| 34 | Natural Flavonoids Targeting Deregulated Cell Cycle Progression in Cancer Cells | Current Drug Targets | 2006 | 92 |
| 35 | Effects of Pharmacist Participation in Intensive Care Units on Clinical and Economic Outcomes of Critically Ill Patients with Thromboembolic or Infarction‐Related Events | Pharmacotherapy | 2009 | 91 |
| 36 | Erythromycin vs Metoclopramide for Facilitating Gastric Emptying and Tolerance to Intragastric Nutrition in Critically Ill Patients | Journal of Parenteral and Enteral Nutrition | 2008 | 90 |
| 37 | Oral Silibinin Inhibits In vivo Human Bladder Tumor Xenograft Growth Involving Down-Regulation of Survivin | Clinical Cancer Research | 2008 | 88 |
| 38 | Chemoprevention of Intestinal Tumorigenesis in APCmin/+ Mice by Silibinin | Cancer Research | 2010 | 84 |
| 39 | Silibinin suppresses growth and induces apoptotic death of human colorectal carcinoma LoVo cells in culture and tumor xenograft | Molecular Cancer Therapeutics | 2009 | 81 |
| 40 | Silibinin inhibits human nonsmall cell lung cancer cell growth through cell‐cycle arrest by modulating expression and function of key cell‐cycle regulators | Molecular Carcinogenesis | 2010 | 81 |
| 41 | Fisetin inhibits various attributes of angiogenesis in vitro and in vivo--implications for angioprevention | Carcinogenesis | 2012 | 80 |
| 42 | Prolonged Period of Cortical Plasticity upon Redox Dysregulation in Fast-Spiking Interneurons | Biological Psychiatry | 2015 | 80 |
| 43 | Synthesis of 19-substituted geldanamycins with altered conformations and their binding to heat shock protein Hsp90 | Nature Chemistry | 2013 | 78 |
| 44 | Sulfur mustard analog induces oxidative stress and activates signaling cascades in the skin of SKH-1 hairless mice | Free Radical Biology and Medicine | 2009 | 76 |
| 45 | Association of Pancreatitis with Glucagon-Like Peptide-1 Agonist Use | Annals of Pharmacotherapy | 2010 | 76 |
| 46 | Inflammatory Biomarkers of Sulfur Mustard Analog 2-Chloroethyl Ethyl Sulfide–Induced Skin Injury in SKH-1 Hairless Mice | Toxicological Sciences | 2009 | 75 |
| 47 | Residue-Specific Adduction of Tubulin by 4-Hydroxynonenal and 4-Oxononenal Causes Cross-Linking and Inhibits Polymerization | Chemical Research in Toxicology | 2007 | 72 |
| 48 | Emerging Role of Anticoagulants and Fibrinolytics in the Treatment of Acute Respiratory Distress Syndrome | Pharmacotherapy | 2007 | 70 |
| 49 | Role of E-cadherin in Antimigratory and Antiinvasive Efficacy of Silibinin in Prostate Cancer Cells | Cancer Prevention Research | 2011 | 70 |
| 50 | Effect of silibinin in human colorectal cancer cells: Targeting the activation of NF‐κB signaling | Molecular Carcinogenesis | 2013 | 69 |
