| # | Title | Journal | Year | Citations |
|---|
| 1 | Hydrogen sulfide is an endogenous stimulator of angiogenesis | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 768 |
| 2 | Zinc and human health: an update | Archives of Toxicology | 2012 | 732 |
| 3 | Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology | Nature Genetics | 2021 | 629 |
| 4 | Hydrogen sulfide and nitric oxide are mutually dependent in the regulation of angiogenesis and endothelium-dependent vasorelaxation | Proceedings of the National Academy of Sciences of the United States of America | 2012 | 572 |
| 5 | Defining the disease liability of variants in the cystic fibrosis transmembrane conductance regulator gene | Nature Genetics | 2013 | 513 |
| 6 | Calcium carbonate phase analysis using XRD and FT-Raman spectroscopy | Analyst, The | 2000 | 487 |
| 7 | PLGA–mPEG nanoparticles of cisplatin: in vitro nanoparticle degradation, in vitro drug release and in vivo drug residence in blood properties | Journal of Controlled Release | 2002 | 452 |
| 8 | Exosomes and Exosome-Inspired Vesicles for Targeted Drug Delivery | Pharmaceutics | 2018 | 390 |
| 9 | Nose-to-brain drug delivery: An update on clinical challenges and progress towards approval of anti-Alzheimer drugs | Journal of Controlled Release | 2018 | 377 |
| 10 | Pegylated Poly(Lactide) and Poly(Lactide-Co-Glycolide) Nanoparticles: Preparation, Properties and Possible Applications in Drug Delivery | Current Drug Delivery | 2004 | 347 |
| 11 | Selectivity of commonly used pharmacological inhibitors for cystathionine β synthase (CBS) and cystathionine γ lyase (CSE) | British Journal of Pharmacology | 2013 | 340 |
| 12 | Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin | Nature Genetics | 2010 | 323 |
| 13 | Quantitative analysis of synthetic calcium carbonate polymorphs using FT-IR spectroscopy | Talanta | 2003 | 316 |
| 14 | Muscle and neuronal nicotinic acetylcholine receptors | FEBS Journal | 2007 | 270 |
| 15 | Computational approaches in target identification and drug discovery | Computational and Structural Biotechnology Journal | 2016 | 270 |
| 16 | Hydrogen sulfide replacement therapy protects the vascular endothelium in hyperglycemia by preserving mitochondrial function | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 254 |
| 17 | Recent advancements in liposomes targeting strategies to cross blood-brain barrier (BBB) for the treatment of Alzheimer's disease | Journal of Controlled Release | 2017 | 251 |
| 18 | Implementing Pharmacogenomics in Europe: Design and Implementation Strategy of the Ubiquitous Pharmacogenomics Consortium | Clinical Pharmacology and Therapeutics | 2017 | 240 |
| 19 | A Potential Role for Multiple Tissue Kallikrein Serine Proteases in Epidermal Desquamation | Journal of Biological Chemistry | 2007 | 235 |
| 20 | Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs | Bioorganic and Medicinal Chemistry | 2010 | 220 |
| 21 | Effect of dose on the biodistribution and pharmacokinetics of PLGA and PLGA–mPEG nanoparticles | International Journal of Pharmaceutics | 2001 | 201 |
| 22 | Multifunctional nanoliposomes with curcumin–lipid derivative and brain targeting functionality with potential applications for Alzheimer disease | European Journal of Medicinal Chemistry | 2014 | 201 |
| 23 | Effect of copolymer composition on the physicochemical characteristics, in vitro stability, and biodistribution of PLGA–mPEG nanoparticles | International Journal of Pharmaceutics | 2003 | 200 |
| 24 | Angiopoietin-2 Causes Inflammation in Vivo by Promoting Vascular Leakage | Journal of Pharmacology and Experimental Therapeutics | 2005 | 200 |
| 25 | Curcumin-decorated nanoliposomes with very high affinity for amyloid-β1-42 peptide | Biomaterials | 2011 | 198 |
| 26 | Functional Roles of Human Kallikrein-related Peptidases | Journal of Biological Chemistry | 2009 | 193 |
| 27 | Editorial: Nicotine and SARS-CoV-2: COVID-19 may be a disease of the nicotinic cholinergic system | Toxicology Reports | 2020 | 191 |
| 28 | Sulfonamide-1,2,4-triazole derivatives as antifungal and antibacterial agents: Synthesis, biological evaluation, lipophilicity, and conformational studies | Bioorganic and Medicinal Chemistry | 2008 | 189 |
| 29 | Hydrogen sulphide and angiogenesis: mechanisms and applications | British Journal of Pharmacology | 2011 | 186 |
| 30 | Investigation of the release mechanism of a sparingly water-soluble drug from solid dispersions in hydrophilic carriers based on physical state of drug, particle size distribution and drug–polymer interactions | European Journal of Pharmaceutics and Biopharmaceutics | 2007 | 185 |
| 31 | The Overgrowth of Calcium Carbonate on Poly(vinyl chloride-co-vinyl acetate-co-maleic acid) | Langmuir | 1999 | 183 |
| 32 | E‐cigarettes generate high levels of aldehydes only in ‘dry puff’ conditions | Addiction | 2015 | 168 |
| 33 | Overcoming barriers by local drug delivery with liposomes | Advanced Drug Delivery Reviews | 2021 | 157 |
| 34 | Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies | Bioorganic and Medicinal Chemistry | 2012 | 150 |
| 35 | Emerging roles of microRNAs as molecular switches in the integrated circuit of the cancer cell | Rna | 2009 | 147 |
| 36 | Global implementation of genomic medicine: We are not alone | Science Translational Medicine | 2015 | 146 |
| 37 | DNA Methylation of Tumor Suppressor and Metastasis Suppressor Genes in Circulating Tumor Cells | Clinical Chemistry | 2011 | 145 |
| 38 | Saffron as a Source of Novel Acetylcholinesterase Inhibitors: Molecular Docking and in Vitro Enzymatic Studies | Journal of Agricultural and Food Chemistry | 2012 | 143 |
| 39 | Systematic documentation and analysis of human genetic variation in hemoglobinopathies using the microattribution approach | Nature Genetics | 2011 | 142 |
| 40 | Inkjet printing of transdermal microneedles for the delivery of anticancer agents | International Journal of Pharmaceutics | 2015 | 141 |
| 41 | Comparison of the effects of e-cigarette vapor with cigarette smoke on lung function and inflammation in mice | American Journal of Physiology - Lung Cellular and Molecular Physiology | 2018 | 138 |
| 42 | Characterization of the enzymatic activity of human kallikrein 6: autoactivation, substrate specificity, and regulation by inhibitors | Biochemical and Biophysical Research Communications | 2003 | 134 |
| 43 | Curcumin-conjugated nanoliposomes with high affinity for Aβ deposits: Possible applications to Alzheimer disease | Nanomedicine: Nanotechnology, Biology, and Medicine | 2013 | 134 |
| 44 | Current smoking, former smoking, and adverse outcome among hospitalized COVID-19 patients: a systematic review and meta-analysis | Therapeutic Advances in Chronic Disease | 2020 | 133 |
| 45 | New polymer electrolytes based on blends of sulfonated polysulfones with polybenzimidazole | Electrochimica Acta | 2001 | 132 |
| 46 | Nicotine absorption from electronic cigarette use: comparison between experienced consumers (vapers) and naïve users (smokers) | Scientific Reports | 2015 | 130 |
| 47 | Realities and expectations of pharmacogenomics and personalized medicine: impact of translating genetic knowledge into clinical practice | Pharmacogenomics | 2010 | 129 |
| 48 | Electronic cigarette use in the European Union: analysis of a representative sample of 27 460 Europeans from 28 countries | Addiction | 2016 | 128 |
| 49 | Anticancer activity of cisplatin-loaded PLGA-mPEG nanoparticles on LNCaP prostate cancer cells | European Journal of Pharmaceutics and Biopharmaceutics | 2007 | 127 |
| 50 | Krüppeling erythropoiesis: an unexpected broad spectrum of human red blood cell disorders due to KLF1 variants | Blood | 2016 | 124 |
