Institute for Organic Chemistry and Chemical Biology

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#	Title	Journal	Year	Citations
1	A Highly Enantioselective Brønsted Acid Catalyzed Cascade Reaction: Organocatalytic Transfer Hydrogenation of Quinolines and their Application in the Synthesis of Alkaloids	Angewandte Chemie - International Edition	2006	681
2	NMR Spectroscopy of RNA	ChemBioChem	2003	428
3	Discovery of protein phosphatase inhibitor classes by biology-oriented synthesis	Proceedings of the National Academy of Sciences of the United States of America	2006	288
4	Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation	Nature Medicine	2016	222
5	Asymmetric Organocatalysis: An Efficient Enantioselective Access to Benzopyranes and Chromenes	Chemistry - A European Journal	2008	210
6	Asymmetric Brønsted Acid Catalysis: Catalytic Enantioselective Synthesis of Highly Biologically Active Dihydroquinazolinones	Angewandte Chemie - International Edition	2009	197
7	Highly Enantioselective Organocatalytic Carbonyl‐Ene Reaction with Strongly Acidic, Chiral Brønsted Acids as Efficient Catalysts	Angewandte Chemie - International Edition	2008	170
8	Activity-dependent spatially localized miRNA maturation in neuronal dendrites	Science	2017	166
9	Structures of RNA Switches: Insight into Molecular Recognition and Tertiary Structure	Angewandte Chemie - International Edition	2007	159
10	Molecular Mechanism of Inhibition of the Human Protein Complex Hsp90–Cdc37, a Kinome Chaperone–Cochaperone, by Triterpene Celastrol	Angewandte Chemie - International Edition	2009	153
11	Asymmetric Iminium Ion Catalysis: An Efficient Enantioselective Synthesis of Pyranonaphthoquinones and β‐Lapachones	Angewandte Chemie - International Edition	2008	149
12	Time-resolved NMR methods resolving ligand-induced RNA folding at atomic resolution	Proceedings of the National Academy of Sciences of the United States of America	2007	126
13	A Highly Enantioselective Brønsted Acid Catalyzed Reaction Cascade	Angewandte Chemie - International Edition	2008	117
14	Metal-Free Catalysts for the Hydrolysis of RNA Derived from Guanidines, 2-Aminopyridines, and 2-Aminobenzimidazoles	Journal of the American Chemical Society	2005	107
15	Light-inducible antimiR-92a as a therapeutic strategy to promote skin repair in healing-impaired diabetic mice	Nature Communications	2017	106
16	Direct observation of the temperature-induced melting process of the Salmonella fourU RNA thermometer at base-pair resolution	Nucleic Acids Research	2010	105
17	Kinetics of Photoinduced RNA Refolding by Real-Time NMR Spectroscopy	Angewandte Chemie - International Edition	2005	98
18	Tandem Phosphorylation of Serines 221 and 318 by Protein Kinase Cδ Coordinates mRNA Binding and Nucleocytoplasmic Shuttling of HuR	Molecular and Cellular Biology	2010	88
19	Ultrafast Dynamics of a Spiropyran in Water	Journal of the American Chemical Society	2012	79
20	Site-Specific Cleavage of RNA by a Metal-Free Artificial Nuclease Attached to Antisense Oligonucleotides	Journal of the American Chemical Society	2006	77
21	Mapping the Landscape of RNA Dynamics with NMR Spectroscopy	Accounts of Chemical Research	2011	77
22	The molecular basis of subtype selectivity of human kinin G-protein-coupled receptors	Nature Chemical Biology	2018	74
23	Four Levels of Wavelength-Selective Uncaging for Oligonucleotides	Organic Letters	2013	72
24	Structure determination of noncanonical RNA motifs guided by 1H NMR chemical shifts	Nature Methods	2014	72
25	Molecular tuning of farnesoid X receptor partial agonism	Nature Communications	2019	71
26	Isotope labeling of mammalian GPCRs in HEK293 cells and characterization of the C-terminus of bovine rhodopsin by high resolution liquid NMR spectroscopy	Journal of Biomolecular NMR	2008	63
27	Residue Specific Ribose and Nucleobase Dynamics of the cUUCGg RNA Tetraloop Motif by MNMR 13C Relaxation	Journal of Biomolecular NMR	2005	61
28	Conformational Dynamics of Bistable RNAs Studied by Time-Resolved NMR Spectroscopy	Journal of the American Chemical Society	2007	61
29	Modulation of the stability of the Salmonella fourU-type RNA thermometer	Nucleic Acids Research	2011	61
30	Spiropyran Photoswitches in the Context of DNA: Synthesis and Photochromic Properties	Chemistry - A European Journal	2013	61
31	The Human Cdc37·Hsp90 Complex Studied by Heteronuclear NMR Spectroscopy	Journal of Biological Chemistry	2009	60
32	Reversible Photoswitching of RNA Hybridization at Room Temperature with an Azobenzene C‐Nucleoside	Chemistry - A European Journal	2015	59
33	NMR Backbone Assignment of a Protein Kinase Catalytic Domain by a Combination of Several Approaches: Application to the Catalytic Subunit of cAMP‐Dependent Protein Kinase	ChemBioChem	2004	58
34	Postsynthetic on Column RNA Labeling via Stille Coupling	Bioconjugate Chemistry	2012	56
35	New NMR experiments for RNA nucleobase resonance assignment and chemical shift analysis of an RNA UUCG tetraloop	Journal of Biomolecular NMR	2004	55
36	Modulation of Compactness and Long-Range Interactions of Unfolded Lysozyme by Single Point Mutations	Angewandte Chemie - International Edition	2004	55
37	Water-Soluble Py-BIPS Spiropyrans as Photoswitches for Biological Applications	Organic Letters	2015	55
38	Exploring the Druggability of Conserved RNA Regulatory Elements in the SARS‐CoV‐2 Genome	Angewandte Chemie - International Edition	2021	55
39	Motional properties of unfolded ubiquitin: a model for a random coil protein	Journal of Biomolecular NMR	2006	54
40	Differential regulation of local mRNA dynamics and translation following long-term potentiation and depression	Proceedings of the National Academy of Sciences of the United States of America	2021	54
41	L11 domain rearrangement upon binding to RNA and thiostrepton studied by NMR spectroscopy	Nucleic Acids Research	2007	53
42	Solution NMR Structure of a Ligand/Hybrid‐2‐G‐Quadruplex Complex Reveals Rearrangements that Affect Ligand Binding	Angewandte Chemie - International Edition	2017	52
43	Photoresponsive Formation of an Intermolecular Minimal G‐Quadruplex Motif	Angewandte Chemie - International Edition	2016	50
44	Regulating Angiogenesis with Light‐Inducible AntimiRs	Angewandte Chemie - International Edition	2013	49
45	Click chemistry facilitates direct labelling and super-resolution imaging of nucleic acids and proteins	RSC Advances	2014	49
46	Editorial: New 1.2 GHz NMR Spectrometers— New Horizons?	Angewandte Chemie - International Edition	2017	49
47	Enzymatic Polymerization of Dimethyl 2,5-Furandicarboxylate and Heteroatom Diamines	ACS Omega	2018	46
48	A Caged Uridine for the Selective Preparation of an RNA Fold and Determination of its Refolding Kinetics by Real-Time NMR	ChemBioChem	2006	45
49	Dissecting the influence of Mg 2+ on 3D architecture and ligand-binding of the guanine-sensing riboswitch aptamer domain	Nucleic Acids Research	2010	44
50	Visible-light-activated photoCORMs: rational design of CO-releasing organic molecules absorbing in the tissue-transparent window	Photochemical and Photobiological Sciences	2018	43

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