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Institute of Clinical Pharmacology
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top-articles
Institute of Clinical Pharmacology
402
(top 1%)
papers
11.7K
(top 1%)
citations
53
(top 1%)
h
-index
85
(top 1%)
g
-index
422
all documents
12.5K
doc citations
2.5K
citing journals
Top Articles
#
Title
Journal
Year
Citations
1
Cyclooxygenase-2 Controls Energy Homeostasis in Mice by de Novo Recruitment of Brown Adipocytes
Science
2010
401
2
Pharmacokinetics of codeine and its metabolite morphine in ultra-rapid metabolizers due to CYP2D6 duplication
Pharmacogenomics Journal
2007
379
3
Pharmacokinetics of Opioids in Liver Disease
Clinical Pharmacokinetics
1999
259
4
Genetic Predictors of the Clinical Response to Opioid Analgesics
Clinical Pharmacokinetics
2004
230
5
S1PR1 on tumor-associated macrophages promotes lymphangiogenesis and metastasis via NLRP3/IL-1β
Journal of Experimental Medicine
2017
216
6
Analgesic effects of morphine and morphine-6-glucuronide in a transcutaneous electrical pain model in healthy volunteers
Clinical Pharmacology and Therapeutics
2003
187
7
Clinical Significance of Results from Olfactory Testing
Laryngoscope
2006
173
8
Different Odor Tests Contribute Differently to the Evaluation of Olfactory Loss
Chemical Senses
2008
148
9
Are μ-opioid receptor polymorphisms important for clinical opioid therapy?
Trends in Molecular Medicine
2005
143
10
The μ-opioid receptor gene polymorphism 118A>G depletes alfentanil-induced analgesia and protects against respiratory depression in homozygous carriers
Pharmacogenetics and Genomics
2006
137
11
A Common Human μ-Opioid Receptor Genetic Variant Diminishes the Receptor Signaling Efficacy in Brain Regions Processing the Sensory Information of Pain
Journal of Biological Chemistry
2009
135
12
Genetically Polymorphic OCT1: Another Piece in the Puzzle of the Variable Pharmacokinetics and Pharmacodynamics of the Opioidergic Drug Tramadol
Clinical Pharmacology and Therapeutics
2011
126
13
Machine learning in pain research
Pain
2018
122
14
Differential Opioid Action on Sensory and Affective Cerebral Pain Processing
Clinical Pharmacology and Therapeutics
2008
121
15
SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia
Nature Medicine
2017
121
16
Current evidence for a genetic modulation of the response to analgesics
Pain
2006
113
17
THP-1 and human peripheral blood mononuclear cell-derived macrophages differ in their capacity to polarize in vitro
Molecular Immunology
2017
111
18
Effects of ABCB1 (multidrug resistance transporter) gene mutations on disposition and central nervous effects of loperamide in healthy volunteers
Pharmacogenetics and Genomics
2003
106
19
Cross-sectional analysis of the influence of currently known pharmacogenetic modulators on opioid therapy in outpatient pain centers
Pharmacogenetics and Genomics
2009
106
20
Anticoagulant Therapy with the Oral Direct Factor Xa Inhibitors Rivaroxaban, Apixaban and Edoxaban and the Thrombin Inhibitor Dabigatran Etexilate in Patients with Hepatic Impairment
Clinical Pharmacokinetics
2013
106
21
Regulation of the heat stress response in
Arabidopsis
by MPK6-targeted phosphorylation of the heat stress factor HsfA2
PeerJ
2013
106
22
Genetic–epigenetic interaction modulates µ-opioid receptor regulation
Human Molecular Genetics
2012
105
23
Genetic variants altering dopamine D2 receptor expression or function modulate the risk of opiate addiction and the dosage requirements of methadone substitution
Pharmacogenetics and Genomics
2009
104
24
5,6-EET Is Released upon Neuronal Activity and Induces Mechanical Pain Hypersensitivity via TRPA1 on Central Afferent Terminals
Journal of Neuroscience
2012
103
25
Identification of Inhibitors of SARS-CoV-2 3CL-Pro Enzymatic Activity Using a Small Molecule in Vitro Repurposing Screen
ACS Pharmacology and Translational Science
2021
101
26
Reduced hyperalgesia in homozygous carriers of a GTP cyclohydrolase 1 haplotype
European Journal of Pain
2008
97
27
Modulation of the central nervous effects of levomethadone by genetic polymorphisms potentially affecting its metabolism, distribution, and drug action
Clinical Pharmacology and Therapeutics
2006
91
28
Genetic modulation of the pharmacological treatment of pain
2009
91
29
The clinical significance of electrophysiological measures of olfactory function
Behavioural Brain Research
2006
90
30
Clinical Usefulness of Self-Rated Olfactory Performance—A Data Science-Based Assessment of 6000 Patients
Chemical Senses
2019
87
31
Characterization of the Micro-Environment of the Testis that Shapes the Phenotype and Function of Testicular Macrophages
Journal of Immunology
2017
86
32
Genetic mutations that prevent pain: implications for future pain medication
Pharmacogenomics
2008
85
33
Comparative clinical effects of hydromorphone and morphine: a meta-analysis
British Journal of Anaesthesia
2011
82
34
The human μ-opioid receptor gene polymorphism 118A > G decreases cortical activation in response to specific nociceptive stimulation.
Behavioral Neuroscience
2006
80
35
Relevance of frequent μ-opioid receptor polymorphisms for opioid activity in healthy volunteers
Pharmacogenomics Journal
2006
80
36
Targeting CYP2J to reduce paclitaxel-induced peripheral neuropathic pain
Proceedings of the National Academy of Sciences of the United States of America
2016
79
37
Fatal Respiratory Depression after??Multiple Intravenous Morphine Injections
Clinical Pharmacokinetics
2006
75
38
Lipoxin and resolvin biosynthesis is dependent on 5‐lipoxygenase activating protein
FASEB Journal
2015
70
39
Macrophages programmed by apoptotic cells promote angiogenesis
via
prostaglandin E
2
FASEB Journal
2011
69
40
Separating brain processing of pain fromthat of stimulus intensity
Human Brain Mapping
2012
69
41
A Dual Modulator of Farnesoid X Receptor and Soluble Epoxide Hydrolase To Counter Nonalcoholic Steatohepatitis
Journal of Medicinal Chemistry
2017
69
42
Evidence for morphine-independent central nervous opioid effects after administration of codeine: Contribution of other codeine metabolites
Clinical Pharmacology and Therapeutics
2006
68
43
Can extremely low or high morphine formation from codeine be predicted prior to therapy initiation?
Pain
2009
68
44
Common non-epigenetic drugs as epigenetic modulators
Trends in Molecular Medicine
2013
68
45
Machine-learned cluster identification in high-dimensional data
Journal of Biomedical Informatics
2017
68
46
IL-38 Ameliorates Skin Inflammation and Limits IL-17 Production from γδ T Cells
Cell Reports
2019
68
47
A GTP cyclohydrolase 1 genetic variant delays cancer pain
Pain
2010
67
48
Inhibition of macrophage fatty acid β-oxidation exacerbates palmitate-induced inflammatory and endoplasmic reticulum stress responses
Diabetologia
2014
64
49
Computed ABC Analysis for Rational Selection of Most Informative Variables in Multivariate Data
PLoS ONE
2015
64
50
PGD2 metabolism in plasma: Kinetics and relationship with bioactivity on DP1 and CRTH2 receptors
Biochemical Pharmacology
2007
63
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