| # | Title | Journal | Year | Citations |
|---|
| 1 | Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2 | Nature | 2004 | 1,039 |
| 2 | Long-term follow-up of hematologic relapse-free survival in a phase 2 study of blinatumomab in patients with MRD in B-lineage ALL | Blood | 2012 | 435 |
| 3 | Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation | Nature Medicine | 2016 | 222 |
| 4 | Elevated endothelin-1 levels after cigarette smoking | Metabolism: Clinical and Experimental | 1994 | 145 |
| 5 | Bioelectrical Impedance Analysis as a Predictor of Survival in Patients with Human Immunodeficiency Virus Infection | Journal of Acquired Immune Deficiency Syndromes | 1995 | 145 |
| 6 | High-dose methotrexate-based immuno-chemotherapy for elderly primary CNS lymphoma patients (PRIMAIN study) | Leukemia | 2017 | 134 |
| 7 | Increased Plasma Levels of Endothelin in Diabetic Patients With Hypertension: An Alternative Viewpoint | American Journal of Hypertension | 1992 | 100 |
| 8 | Long-term relapse-free survival in a phase 2 study of blinatumomab for the treatment of patients with minimal residual disease in B-lineage acute lymphoblastic leukemia | Haematologica | 2017 | 81 |
| 9 | Heterogeneous lipoprotein (a) size isoforms differ by their interaction with the low density lipoprotein receptor and the low density lipoprotein receptor-related protein/α2-macroglobulin receptor | FEBS Letters | 1993 | 74 |
| 10 | Gallstone dissolution with methyltert-butyl ether in 120 patients?Efficacy and safety | Digestive Diseases and Sciences | 1991 | 65 |
| 11 | Clinical Course of Myelodysplastic Syndromes | Hematology/Oncology Clinics of North America | 1992 | 49 |
| 12 | The Effect of α-Lipoic Acid on the Neurovascular Reflex Arc in Patients with Diabetic Neuropathy Assessed by Capillary Microscopy | Microvascular Research | 1999 | 41 |
| 13 | An endogenous retroviral long terminal repeat at the HLA-DQB1 gene locus confers susceptibility to rheumatoid arthritis | Human Immunology | 1999 | 39 |
| 14 | Safety and efficacy of Temsirolimus in combination with Bendamustine and Rituximab in relapsed mantle cell and follicular lymphoma | Leukemia | 2015 | 39 |
| 15 | Fluvastatin therapy improves microcirculation in patients with hyperlipidaemia | Atherosclerosis | 2001 | 38 |
| 16 | Dissolution of gallbladder stones with methyl tert-butyl ether and stone recurrence: a European survey | Digestive Diseases and Sciences | 1998 | 37 |
| 17 | Studies About Unconjugated Androstenediol in Human Peripheral Plasma1 | Journal of Clinical Endocrinology and Metabolism | 1973 | 33 |
| 18 | Pharmacodynamic aspects of tolbutamide, glibenclamide, glibornuride and glisoxepide | Diabetologia | 1971 | 32 |
| 19 | High performance liquid chromatographic determination of free and conjugated bile acids in serum, liver biopsies, bile, gastric juice and feces by fluorescence labeling | Clinica Chimica Acta | 1993 | 31 |
| 20 | Toxicity of ethanol and acetaldehyde in hepatocytes treated with ursodeoxycholic or tauroursodeoxycholic acid | Biochimica Et Biophysica Acta - Molecular Cell Research | 2004 | 30 |
| 21 | Treatment of Myelodysplastic Syndromes with Hematopoietic Growth Factors | Hematology/Oncology Clinics of North America | 1992 | 29 |
| 22 | Post-myocardial infarction heart failure dysregulates the bone vascular niche | Nature Communications | 2021 | 23 |
| 23 | The effect of bile salts and calcium on isolated rat liver mitochondria | Biochimica Et Biophysica Acta - Molecular Basis of Disease | 1999 | 21 |
| 24 | Characterization of the gene for apolipoprotein E5-Frankfurt (Gln81 -> Lys, Cys112 -> Arg) by polymerase chain reaction, restriction isotyping, and temperature gradient gel electrophoresis | Electrophoresis | 1993 | 19 |
| 25 | Alteration of xanthine oxidase activity in sinusoidal endothelial cells and morphological changes of kupffer cells in hypoxic and reoxygenated rat liver | Hepatology | 1995 | 19 |
| 26 | Inflammatory signatures are associated with increased mortality after transfemoral transcatheter aortic valve implantation | ESC Heart Failure | 2020 | 19 |
| 27 | Pharmacodynamic aspects of tolbutamide, glibenclamide, glibornuride, and glisoxepide | Diabetologia | 1971 | 17 |
| 28 | HLA Antigens in Patients with Idiopathic Hemochromatosis (IH) | Tissue Antigens | 1978 | 17 |
| 29 | Beat-to-beat variation of heart rate in diabetic patients with autonomic neuropathy and in completely cardiac denervated patients following orthotopic heart transplantation | International Journal of Cardiology | 1991 | 16 |
| 30 | Double long-wire technique for percutaneous transluminal coronary angioplasty for narrowings at major bifurcations | American Journal of Cardiology | 1987 | 15 |
| 31 | New developments in the treatment of type 1 diabetes mellitus | Experimental and Clinical Endocrinology and Diabetes | 1999 | 14 |
| 32 | Screening for iron deficiency in surgical patients based on noninvasive zinc protoporphyrin measurements | Transfusion | 2020 | 14 |
| 33 | Pathogenesis of pigment stones and medical treatment | Journal of Gastroenterology and Hepatology (Australia) | 1994 | 12 |
| 34 | The inhibiting effect of trilostane on adrenal steroid synthesis: Hormonal and morphological alterations induced by subchronic trilostane treatment in normal rats | Research in Experimental Medicine | 1982 | 11 |
| 35 | The somatostatin analogue octreotide protects against ethanol-induced microcirculatory stasis and elevated vascular permeability in rat gastric mucosa | European Journal of Pharmacology | 1994 | 11 |
| 36 | In vivo evidence that human atrial natriuretic factor-(99–126) (hANF) stimulates parasympathetic activity in man | European Journal of Clinical Pharmacology | 1990 | 10 |
| 37 | Continuous recording of local myocardial function in normal and ischemic myocardium | Basic Research in Cardiology | 1976 | 9 |
| 38 | The effect of metoclopramide and haloperidol on plasma renin activity and aldosterone levels in rats | Research in Experimental Medicine | 1983 | 8 |
| 39 | Manual and automatic gallstone dissolution with methyltert-butyl ether | Digestive Diseases and Sciences | 1994 | 8 |
| 40 | Polymorphisms of tumor necrosis factor receptor 2 are not associated with insulin‐dependent diabetes mellitus or Graves' disease | Tissue Antigens | 1997 | 7 |
| 41 | Distribution of Testosterone in Plasma Proteins during Replacement Therapy with Testosterone Enanthate in Patients Suffering from Hypogonadism* | Andrologia | 2009 | 7 |
| 42 | Final Results of a Phase I/II Trial of the Combination Bendamustine and Rituximab With Temsirolimus (BeRT) in Relapsed Mantle Cell Lymphoma and Follicular Lymphoma | HemaSphere | 2020 | 7 |
| 43 | Aldosterone and prolactin responsiveness after prolonged treatment of congestive heart failure with captopril | European Journal of Clinical Pharmacology | 1985 | 6 |
| 44 | Activity of Cellular Thymidine Kinase 1 in PBMC of HIV-1-Infected Patients: Novel Therapy Marker | Infection | 2000 | 6 |
| 45 | Isolation of Lipoprotein (a) Using the Regenerate of a Dextran Sulfate Cellulose LDL Apheresis System | Protein Expression and Purification | 1994 | 5 |
| 46 | The Bioengineered Combo Dual-Therapy CD34 Antibody-Covered Sirolimus-Eluting Coronary Stent in Patients with Chronic Total Occlusion Evaluated by Clinical Outcome and Optical Coherence Tomography Imaging Analysis | Journal of Clinical Medicine | 2021 | 5 |
| 47 | Diurnal Rhythm of Bile Lipid Composition after Cholecystectomy and Papillotomy: Postpapillotomy Biliary Lithogenicity | Scandinavian Journal of Gastroenterology | 1985 | 4 |
| 48 | Studies on the site of action of tolbutamide in the lipolytic system | Diabetologia | 1972 | 3 |
| 49 | Clinical examination, laparoscopy and histology in the diagnosis of liver diseases A prospective study in 900 patients | Acta Endoscopica | 1982 | 3 |
| 50 | Blind liver biopsy or guided biopsy? A prospective study | Acta Endoscopica | 1982 | 3 |
