| # | Title | Journal | Year | Citations |
|---|
| 1 | Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines | Journal of Extracellular Vesicles | 2018 | 6,961 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 3 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 4 | Analysis of shared heritability in common disorders of the brain | Science | 2018 | 1,085 |
| 5 | AAA+ proteins: have engine, will work | Nature Reviews Molecular Cell Biology | 2005 | 1,009 |
| 6 | Functional recovery in parkinsonian monkeys treated with GDNF | Nature | 1996 | 940 |
| 7 | The Beclin 1–VPS34 complex – at the crossroads of autophagy and beyond | Trends in Cell Biology | 2010 | 687 |
| 8 | Loss of FBP1 by Snail-Mediated Repression Provides Metabolic Advantages in Basal-like Breast Cancer | Cancer Cell | 2013 | 660 |
| 9 | Neuro-inflammation induced by lipopolysaccharide causes cognitive impairment through enhancement of beta-amyloid generation | Journal of Neuroinflammation | 2008 | 620 |
| 10 | Function and Regulation of Yeast Hexose Transporters | Microbiology and Molecular Biology Reviews | 1999 | 616 |
| 11 | Transcriptome of Arabidopsis leaf senescence | Plant, Cell and Environment | 2004 | 536 |
| 12 | Effective fiber hypertrophy in satellite cell-depleted skeletal muscle | Development (Cambridge) | 2011 | 531 |
| 13 | Estradiol Protects against Ischemic Injury | Journal of Cerebral Blood Flow and Metabolism | 1998 | 520 |
| 14 | A comprehensive review of EEG-based brain–computer interface paradigms | Journal of Neural Engineering | 2019 | 512 |
| 15 | Polymyxin B Sulfate and Colistin: Old Antibiotics for Emerging Multiresistant Gram-Negative Bacteria | Annals of Pharmacotherapy | 1999 | 492 |
| 16 | Alternative splicing and disease | Biochimica Et Biophysica Acta - Molecular Basis of Disease | 2009 | 468 |
| 17 | Increase in Single L-Type Calcium Channels in Hippocampal Neurons During Aging | Science | 1996 | 452 |
| 18 | Estradiol Modulates bcl-2 in Cerebral Ischemia: A Potential Role for Estrogen Receptors | Journal of Neuroscience | 1999 | 435 |
| 19 | Intraoperative Transfusion of 1 U to 2 U Packed Red Blood Cells Is Associated with Increased 30-Day Mortality, Surgical-Site Infection, Pneumonia, and Sepsis in General Surgery Patients | Journal of the American College of Surgeons | 2009 | 412 |
| 20 | Consequences of oxidative stress in age-related macular degeneration | Molecular Aspects of Medicine | 2012 | 412 |
| 21 | Vitamin D Hormone Confers Neuroprotection in Parallel with Downregulation of L-Type Calcium Channel Expression in Hippocampal Neurons | Journal of Neuroscience | 2001 | 402 |
| 22 | Disrupting the Interaction of BRD4 with Diacetylated Twist Suppresses Tumorigenesis in Basal-like Breast Cancer | Cancer Cell | 2014 | 401 |
| 23 | G9a interacts with Snail and is critical for Snail-mediated E-cadherin repression in human breast cancer | Journal of Clinical Investigation | 2012 | 400 |
| 24 | The hemodynamics of cardiac tamponade and constrictive pericarditis | American Journal of Cardiology | 1970 | 399 |
| 25 | Recent Advances in Flow Cytometry: Application to the Diagnosis of Hematologic Malignancy | Blood | 1997 | 390 |
| 26 | Importance of Weight Management in Type 2 Diabetes: Review with Meta-analysis of Clinical Studies | Journal of the American College of Nutrition | 2003 | 374 |
| 27 | Inducible depletion of satellite cells in adult, sedentary mice impairs muscle regenerative capacity without affecting sarcopenia | Nature Medicine | 2015 | 358 |
| 28 | Pharmacogenetics and pharmacogenomics of schizophrenia: a review of last decade of research | Molecular Psychiatry | 2007 | 331 |
| 29 | Tooth loss, dementia and neuropathology in the Nun Study | Journal of the American Dental Association | 2007 | 307 |
| 30 | Carbohydrate and Fiber Recommendations for Individuals with Diabetes: A Quantitative Assessment and Meta-Analysis of the Evidence | Journal of the American College of Nutrition | 2004 | 290 |
| 31 | Involvement of hippocampal synaptic plasticity in age-related memory decline | Brain Research Reviews | 1999 | 285 |
| 32 | Direct detection of ototoxicant-induced reactive oxygen species generation in cochlear explants | Hearing Research | 1996 | 283 |
| 33 | Opioid use disorder | Nature Reviews Disease Primers | 2020 | 278 |
| 34 | Application of a new phased-array ultrasound imaging catheter in the assessment of vascular dimensions. In vivo comparison to cineangiography. | Circulation | 1990 | 273 |
| 35 | Identification of glucose-regulated miRNAs from pancreatic β cells reveals a role for miR-30d in insulin transcription | Rna | 2009 | 262 |
| 36 | Metabolic Reprogramming of Cancer-Associated Fibroblasts by IDH3α Downregulation | Cell Reports | 2015 | 258 |
| 37 | Alpha1-adrenergic receptors: new insights and directions | Journal of Pharmacology and Experimental Therapeutics | 2001 | 258 |
| 38 | Serum folate and the severity of atrophy of the neocortex in Alzheimer disease: findings from the Nun Study | American Journal of Clinical Nutrition | 2000 | 256 |
| 39 | PSYCHOMETRICS FOR TWO SHORT FORMS OF THE CENTER FOR EPIDEMIOLOGIC STUDIES-DEPRESSION SCALE | Issues in Mental Health Nursing | 1998 | 255 |
| 40 | Rapid repurposing of drugs for COVID-19 | Science | 2020 | 253 |
| 41 | Microneedles permit transdermal delivery of a skin-impermeant medication to humans | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 248 |
| 42 | Inflammasome Activation Triggers Blood Clotting and Host Death through Pyroptosis | Immunity | 2019 | 246 |
| 43 | Mitochondrial DNA damage and its potential role in retinal degeneration | Progress in Retinal and Eye Research | 2008 | 231 |
| 44 | The YTH Domain Is a Novel RNA Binding Domain | Journal of Biological Chemistry | 2010 | 226 |
| 45 | Regulation of the muscle fiber micro environment by activated satellite cells during hypertrophy | FASEB Journal | 2014 | 225 |
| 46 | Campylobacter jejuni Cytolethal Distending Toxin Causes a G 2 -Phase Cell Cycle Block | Infection and Immunity | 1998 | 225 |
| 47 | Oxidative stress and metal carcinogenesis | Free Radical Biology and Medicine | 2012 | 223 |
| 48 | Dietary fiber and coronary heart disease | Critical Reviews in Food Science and Nutrition | 1990 | 222 |
| 49 | Minireview: Neuroprotective Effects of Estrogen—New Insights into Mechanisms of Action | Endocrinology | 2001 | 221 |
| 50 | A Theory-Based Model for Teaching and Assessing Residents in the Operating Room | Journal of Surgical Education | 2013 | 221 |
