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Top Articles

#TitleJournalYearCitations
1Obesity cardiomyopathy: evidence, mechanisms, and therapeutic implicationsPhysiological Reviews2021150
2Stapled Helical Peptides Bearing Different Anchoring ResiduesChemical Reviews2020134
3TNF antagonist sensitizes synovial fibroblasts to ferroptotic cell death in collagen-induced arthritis mouse modelsNature Communications202278
4Prevalence, awareness, and treatment of anemia in Chinese patients with nondialysis chronic kidney diseaseMedicine (United States)201670
5CD147 antibody specifically and effectively inhibits infection and cytokine storm of SARS-CoV-2 and its variants delta, alpha, beta, and gammaSignal Transduction and Targeted Therapy202164
6Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2Nature Microbiology202263
7mRNA Delivery by a pH‐Responsive DNA Nano‐HydrogelSmall202152
8Stimulus-responsive self-assembled prodrugs in cancer therapyChemical Science202248
9Rapid and sensitive detection of PD-L1 exosomes using Cu-TCPP 2D MOF as a SPR sensitizerBiosensors and Bioelectronics202243
10Meningeal lymphatic vessels mediate neurotropic viral drainage from the central nervous systemNature Neuroscience202243
113D bioprinting for fabricating artificial skin tissueColloids and Surfaces B: Biointerfaces202139
12C(sp3)–H functionalization with isocyanidesOrganic Chemistry Frontiers202138
13ADAR2 increases in exercised heart and protects against myocardial infarction and doxorubicin-induced cardiotoxicityMolecular Therapy202236
14Image denoising based on the adaptive weighted TV regularizationSignal Processing202035
15Gut microbiome mediates the protective effects of exercise after myocardial infarctionMicrobiome202235
16Exercise training maintains cardiovascular health: signaling pathways involved and potential therapeuticsSignal Transduction and Targeted Therapy202234
17Exosomes: Multifaceted Messengers in AtherosclerosisCurrent Atherosclerosis Reports202033
183D bioprinting of proangiogenic constructs with induced immunomodulatory microenvironments through a dual cross-linking procedure using laponite incorporated bioinkComposites Part B: Engineering202233
19Ginger Alleviates DSS-Induced Ulcerative Colitis Severity by Improving the Diversity and Function of Gut MicrobiotaFrontiers in Pharmacology202132
20miR-486 attenuates cardiac ischemia/reperfusion injury and mediates the beneficial effect of exercise for myocardial protectionMolecular Therapy202232
21CRISPR/Cas9-Mediated miR-29b Editing as a Treatment of Different Types of Muscle Atrophy in MiceMolecular Therapy202031
22Tissue Engineering Strategies for Peripheral Nerve RegenerationFrontiers in Neurology202130
23Bioprinted Constructs that Mimic the Ossification Center Microenvironment for Targeted Innervation in Bone RegenerationAdvanced Functional Materials202230
24Irisin alleviates FFA induced β-cell insulin resistance and inflammatory response through activating PI3K/AKT/FOXO1 signaling pathwayEndocrine202229
25Near-Infrared Fluorescent Probes as Imaging and Theranostic Modalities for Amyloid-Beta and Tau Aggregates in Alzheimer’s DiseaseJournal of Medicinal Chemistry202229
26Inhibition of lncRNA MAAT Controls Multiple Types of Muscle Atrophy by cis- and trans-Regulatory ActionsMolecular Therapy202126
27Recent advances in cell membrane camouflage-based biosensing applicationBiosensors and Bioelectronics202126
28Exercise attenuates angiotensinⅡ-induced muscle atrophy by targeting PPARγ/miR-29bJournal of Sport and Health Science202225
29Exercise downregulates HIPK2 and HIPK2 inhibition protects against myocardial infarctionEBioMedicine202125
30Tanshinone IIA Protects Against Cerebral Ischemia Reperfusion Injury by Regulating Microglial Activation and Polarization via NF-κB PathwayFrontiers in Pharmacology202124
31A Novel Anti-Osteoporosis Mechanism of VK2: Interfering with Ferroptosis via AMPK/SIRT1 Pathway in Type 2 Diabetic OsteoporosisJournal of Agricultural and Food Chemistry202324
32HIPK2 phosphorylates HDAC3 for NF-κB acetylation to ameliorate colitis-associated colorectal carcinoma and sepsisProceedings of the National Academy of Sciences of the United States of America202123
33A DNA logic gate with dual-anchored proximity aptamers for the accurate identification of circulating tumor cellsChemical Communications202022
34Non-coding RNA basis of muscle atrophyMolecular Therapy - Nucleic Acids202122
35Generating 3D human cardiac constructs from pluripotent stem cellsEBioMedicine202222
36Programmable DNA-Fueled Electrochemical Analysis of Lung Cancer ExosomesAnalytical Chemistry202222
37Cysteine carboxyethylation generates neoantigens to induce HLA-restricted autoimmunityScience202322
38Tetraalkylammonium-l-tartrate ionic liquids as sole chiral selectors in capillary electrophoresisSeparation and Purification Technology202121
39Targets identified from exercised heart: killing multiple birds with one stoneNpj Regenerative Medicine202121
40Therapeutic effect of SIRT3 on glucocorticoid-induced osteonecrosis of the femoral head via intracellular oxidative suppressionFree Radical Biology and Medicine202121
41Physical Exercise Protects Against Endothelial Dysfunction in Cardiovascular and Metabolic DiseasesJournal of Cardiovascular Translational Research202221
42Bone Regeneration Using MMP-Cleavable Peptides-Based HydrogelsGels202121
43Excessive mechanical stress-induced intervertebral disc degeneration is related to Piezo1 overexpression triggering the imbalance of autophagy/apoptosis in human nucleus pulpousArthritis Research and Therapy202221
44Early Warning Indicators of Severe COVID-19: A Single-Center Study of Cases From Shanghai, ChinaFrontiers in Medicine202020
45Two Reference-Quality Sea Snake Genomes Reveal Their Divergent Evolution of Adaptive Traits and Venom SystemsMolecular Biology and Evolution202120
46Magnetic field-aligned Fe3O4-coated silver magnetoplasmonic nanochain with enhanced sensitivity for detection of Siglec-15Biosensors and Bioelectronics202120
47Photothermal and Photodynamic Therapies via NIR-Activated Nanoagents in Combating Alzheimer’s DiseaseACS Biomaterials Science and Engineering202117
48Evaluation of a composite nanomaterial consist of gold nanoparticles and graphene-carbon nitride as capillary electrochromatography stationary phase for enantioseparationMicrochemical Journal202117
49Gelsevirine improves age-related and surgically induced osteoarthritis in mice by reducing STING availability and local inflammationBiochemical Pharmacology202217
50Extracellular vesicles enclosed‐miR‐421 suppresses air pollution (PM2.5)‐induced cardiac dysfunction via ACE2 signallingJournal of Extracellular Vesicles202217