| # | Title | Journal | Year | Citations |
|---|
| 1 | Better reporting of interventions: template for intervention description and replication (TIDieR) checklist and guide | BMJ, The | 2014 | 5,661 |
| 2 | Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials | BMJ: British Medical Journal | 2011 | 4,743 |
| 3 | Biological, clinical and population relevance of 95 loci for blood lipids | Nature | 2010 | 3,249 |
| 4 | A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease | Nature Genetics | 2015 | 2,054 |
| 5 | Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study | Lancet, The | 2012 | 1,937 |
| 6 | Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease | Nature Genetics | 2011 | 1,685 |
| 7 | Comparison of Two Methods to Detect Publication Bias in Meta-analysis | JAMA - Journal of the American Medical Association | 2006 | 1,658 |
| 8 | Large-scale association analysis identifies new risk loci for coronary artery disease | Nature Genetics | 2013 | 1,439 |
| 9 | What to add to nothing? Use and avoidance of continuity corrections in meta-analysis of sparse data | Statistics in Medicine | 2004 | 1,376 |
| 10 | Sedentary time in adults and the association with diabetes, cardiovascular disease and death: systematic review and meta-analysis | Diabetologia | 2012 | 1,371 |
| 11 | Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants | Nature Genetics | 2007 | 1,298 |
| 12 | Contour-enhanced meta-analysis funnel plots help distinguish publication bias from other causes of asymmetry | Journal of Clinical Epidemiology | 2008 | 1,291 |
| 13 | Synthesising qualitative and quantitative evidence: A review of possible methods | Journal of Health Services Research and Policy | 2005 | 1,270 |
| 14 | Meta-analysis of individual participant data: rationale, conduct, and reporting | BMJ: British Medical Journal | 2010 | 1,256 |
| 15 | Conducting a critical interpretive synthesis of the literature on access to healthcare by vulnerable groups | BMC Medical Research Methodology | 2006 | 1,217 |
| 16 | A framework for the investigation of pleiotropy in two‐sample summary data Mendelian randomization | Statistics in Medicine | 2017 | 975 |
| 17 | Pharmacological and lifestyle interventions to prevent or delay type 2 diabetes in people with impaired glucose tolerance: systematic review and meta-analysis | BMJ: British Medical Journal | 2007 | 930 |
| 18 | Mapping genomic loci implicates genes and synaptic biology in schizophrenia | Nature | 2022 | 929 |
| 19 | Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits | Nature Genetics | 2018 | 924 |
| 20 | Evidence Synthesis for Decision Making 2 | Medical Decision Making | 2013 | 899 |
| 21 | LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis | Bioinformatics | 2017 | 822 |
| 22 | Identification of seven loci affecting mean telomere length and their association with disease | Nature Genetics | 2013 | 808 |
| 23 | Development and validation of a Hospital Frailty Risk Score focusing on older people in acute care settings using electronic hospital records: an observational study | Lancet, The | 2018 | 806 |
| 24 | The epidemiology and global burden of autism spectrum disorders | Psychological Medicine | 2015 | 801 |
| 25 | Assessing the suitability of summary data for two-sample Mendelian randomization analyses using MR-Egger regression: the role of the I2 statistic | International Journal of Epidemiology | 2016 | 787 |
| 26 | Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease | Nature Genetics | 2017 | 783 |
| 27 | Autism spectrum disorder | Nature Reviews Disease Primers | 2020 | 746 |
| 28 | Epidemiology of Autism Spectrum Disorders in Adults in the Community in England | Archives of General Psychiatry | 2011 | 725 |
| 29 | A checklist for identifying determinants of practice: A systematic review and synthesis of frameworks and taxonomies of factors that prevent or enable improvements in healthcare professional practice | Implementation Science | 2013 | 701 |
| 30 | DNA methylation and body-mass index: a genome-wide analysis | Lancet, The | 2014 | 686 |
| 31 | Detecting pleiotropy in Mendelian randomisation studies with summary data and a continuous outcome | Statistics in Medicine | 2015 | 671 |
| 32 | Guidelines for performing Mendelian randomization investigations | Wellcome Open Research | 2019 | 661 |
| 33 | Neurological and developmental outcome in extremely preterm children born in England in 1995 and 2006: the EPICure studies | BMJ, The | 2012 | 647 |
| 34 | Progress in cancer survival, mortality, and incidence in seven high-income countries 1995–2014 (ICBP SURVMARK-2): a population-based study | Lancet Oncology, The | 2019 | 634 |
| 35 | Effectiveness of the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: cluster randomised controlled trial | BMJ: British Medical Journal | 2008 | 617 |
| 36 | Using simulation studies to evaluate statistical methods | Statistics in Medicine | 2019 | 597 |
| 37 | Meta-analysis and imputation refines the association of 15q25 with smoking quantity | Nature Genetics | 2010 | 581 |
| 38 | Adjusting for treatment effects in studies of quantitative traits: antihypertensive therapy and systolic blood pressure | Statistics in Medicine | 2005 | 571 |
| 39 | Tailored interventions to overcome identified barriers to change: effects on professional practice and health care outcomes | Statistics in Medicine | 2010 | 568 |
| 40 | Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults | Journal of the American College of Cardiology | 2018 | 557 |
| 41 | Performance of the trim and fill method in the presence of publication bias and between-study heterogeneity | Statistics in Medicine | 2007 | 544 |
| 42 | In meta-analyses of proportion studies, funnel plots were found to be an inaccurate method of assessing publication bias | Journal of Clinical Epidemiology | 2014 | 514 |
| 43 | Evidence Synthesis for Decision Making 4 | Medical Decision Making | 2013 | 513 |
| 44 | Guidelines for performing Mendelian randomization investigations | Wellcome Open Research | 2019 | 511 |
| 45 | Explaining Michigan: Developing an Ex Post Theory of a Quality Improvement Program | Milbank Quarterly | 2011 | 507 |
| 46 | Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk | Nature Genetics | 2017 | 492 |
| 47 | Recent developments in meta-analysis | Statistics in Medicine | 2008 | 491 |
| 48 | Anxiety and depression in adults with autism spectrum disorder: a systematic review and meta-analysis | Psychological Medicine | 2019 | 483 |
| 49 | Prevalence and correlates of self-reported psychotic symptoms in the British population | British Journal of Psychiatry | 2004 | 482 |
| 50 | A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium | Nature Genetics | 2009 | 481 |
