| # | Title | Journal | Year | Citations |
|---|
| 1 | Identification of a novel non-coding RNA, MIAT, that confers risk of myocardial infarction | Journal of Human Genetics | 2006 | 597 |
| 2 | Japan Atherosclerosis Society (JAS) Guidelines for Prevention of Atherosclerotic Cardiovascular Diseases 2017 | Journal of Atherosclerosis and Thrombosis | 2018 | 541 |
| 3 | JCS 2018 Guideline on Diagnosis and Treatment of Acute Coronary Syndrome | Circulation Journal | 2019 | 324 |
| 4 | Screening and eradication of Helicobacter pylori for gastric cancer prevention: the Taipei global consensus | Gut | 2020 | 239 |
| 5 | A Scoring System to Stratify Curability after Endoscopic Submucosal Dissection for Early Gastric Cancer: “eCura system” | American Journal of Gastroenterology | 2017 | 198 |
| 6 | Evaluation of combination therapy using aciclovir and corticosteroid in adult patients with herpes simplex virus encephalitis | Journal of Neurology, Neurosurgery and Psychiatry | 2005 | 190 |
| 7 | Apoptosis and non-alcoholic fatty liver diseases | World Journal of Gastroenterology | 2018 | 189 |
| 8 | Molecular Mechanisms Driving Progression of Liver Cirrhosis towards Hepatocellular Carcinoma in Chronic Hepatitis B and C Infections: A Review | International Journal of Molecular Sciences | 2019 | 184 |
| 9 | High-Dose Versus Low-Dose Pitavastatin in Japanese Patients With Stable Coronary Artery Disease (REAL-CAD) | Circulation | 2018 | 174 |
| 10 | DPPX antibody–associated encephalitis | Neurology | 2017 | 170 |
| 11 | Seven-day vonoprazan and low-dose amoxicillin dual therapy as first-line Helicobacter pylori treatment: a multicentre randomised trial in Japan | Gut | 2020 | 148 |
| 12 | Is radical surgery necessary in all patients who do not meet the curative criteria for endoscopic submucosal dissection in early gastric cancer? A multi-center retrospective study in Japan | Journal of Gastroenterology | 2017 | 111 |
| 13 | Dedifferentiated fat cells convert to cardiomyocyte phenotype and repair infarcted cardiac tissue in rats | Journal of Molecular and Cellular Cardiology | 2009 | 109 |
| 14 | Conventional versus traction-assisted endoscopic submucosal dissection for gastric neoplasms: a multicenter, randomized controlled trial (with video) | Gastrointestinal Endoscopy | 2018 | 109 |
| 15 | Defective autophagy in vascular smooth muscle cells enhances cell death and atherosclerosis | Autophagy | 2018 | 104 |
| 16 | Qualitative and Quantitative Changes in Coronary Plaque Associated With Atorvastatin Therapy | Circulation Journal | 2009 | 98 |
| 17 | Effects of Evolocumab (AMG 145), a Monoclonal Antibody to PCSK9, in Hypercholesterolemic, Statin-Treated Japanese Patients at High Cardiovascular Risk | Circulation Journal | 2014 | 97 |
| 18 | Losartan Improves the Impaired Function of Endothelial Progenitor Cells in Hypertension via an Antioxidant Effect | Hypertension Research | 2007 | 95 |
| 19 | Width and depth of resection for small colorectal polyps: hot versus cold snare polypectomy | Gastrointestinal Endoscopy | 2018 | 94 |
| 20 | Oxidative Stress on Progenitor and Stem Cells in Cardiovascular Diseases | Current Pharmaceutical Biotechnology | 2006 | 93 |
| 21 | A Phase 3 Study of Evolocumab (AMG 145) in Statin-Treated Japanese Patients at High Cardiovascular Risk | American Journal of Cardiology | 2016 | 93 |
| 22 | Impact of Biomarkers of Inflammation and Extracellular Matrix Turnover on the Outcome of Atrial Fibrillation Ablation: Importance of Matrix Metalloproteinase-2 as a Predictor of Atrial Fibrillation Recurrence | Journal of Cardiovascular Electrophysiology | 2011 | 92 |
| 23 | Does Location of Epicardial Adipose Tissue Correspond to Endocardial High Dominant Frequency or Complex Fractionated Atrial Electrogram Sites During Atrial Fibrillation? | Circulation: Arrhythmia and Electrophysiology | 2012 | 92 |
| 24 | Exosomes and Hepatocellular Carcinoma: From Bench to Bedside | International Journal of Molecular Sciences | 2019 | 91 |
| 25 | Oral rivaroxaban for Japanese patients with symptomatic venous thromboembolism – the J-EINSTEIN DVT and PE program | Thrombosis Journal | 2015 | 90 |
| 26 | Effects of an ARB on Endothelial Progenitor Cell Function and Cardiovascular Oxidation in Hypertension | American Journal of Hypertension | 2008 | 89 |
| 27 | Association Between Epicardial Adipose Tissue Volumes on 3-Dimensional Reconstructed CT Images and Recurrence of Atrial Fibrillation After Catheter Ablation | Circulation Journal | 2011 | 89 |
| 28 | The Efficacy and Tolerability of a Triple Therapy Containing a Potassium-Competitive Acid Blocker Compared With a 7-Day PPI-Based Low-Dose Clarithromycin Triple Therapy | American Journal of Gastroenterology | 2016 | 88 |
| 29 | Diabetes Mellitus Is a Major Negative Determinant of Coronary Plaque Regression During Statin Therapy in Patients With Acute Coronary Syndrome - Serial Intravascular Ultrasound Observations From the Japan Assessment of Pitavastatin and Atorvastatin in Acute Coronary Syndrome Trial (the JAPAN-ACS Trial) - | Circulation Journal | 2010 | 86 |
| 30 | Functional Precision Medicine Provides Clinical Benefit in Advanced Aggressive Hematologic Cancers and Identifies Exceptional Responders | Cancer Discovery | 2022 | 77 |
| 31 | Moderate low temperature preserves the stemness of neural stem cells and suppresses apoptosis of the cells via activation of the cold-inducible RNA binding protein | Brain Research | 2010 | 74 |
| 32 | Transcriptional inhibition of progressive renal disease by gene silencing pyrrole–imidazole polyamide targeting of the transforming growth factor-β1 promoter | Kidney International | 2011 | 73 |
| 33 | Complement 3 activates the renal renin-angiotensin system by induction of epithelial-to-mesenchymal transition of the nephrotubulus in mice | American Journal of Physiology - Renal Physiology | 2013 | 72 |
| 34 | APASL HCV guidelines of virus-eradicated patients by DAA on how to monitor HCC occurrence and HBV reactivation | Hepatology International | 2019 | 72 |
| 35 | Development of Helicobacter pylori treatment: How do we manage antimicrobial resistance? | World Journal of Gastroenterology | 2019 | 72 |
| 36 | A type 2 ryanodine receptor variant associated with reduced Ca2+ release and short-coupled torsades de pointes ventricular arrhythmia | Heart Rhythm | 2017 | 69 |
| 37 | Conventional versus traction-assisted endoscopic submucosal dissection for large esophageal cancers: a multicenter, randomized controlled trial (with video) | Gastrointestinal Endoscopy | 2020 | 69 |
| 38 | History and future perspectives in Japanese guidelines for endoscopic resection of early gastric cancer | Digestive Endoscopy | 2020 | 67 |
| 39 | Comparison of Quantitative EEGs Between Parkinson Disease and Age-Adjusted Normal Controls | Journal of Clinical Neurophysiology | 2008 | 66 |
| 40 | Molecular Mechanisms: Connections between Nonalcoholic Fatty Liver Disease, Steatohepatitis and Hepatocellular Carcinoma | International Journal of Molecular Sciences | 2020 | 66 |
| 41 | Comparison of In Vivo Tissue Temperature Profile and Lesion Geometry for Radiofrequency Ablation With High Power–Short Duration and Moderate Power–Moderate Duration: Effects of Thermal Latency and Contact Force on Lesion Formation | Circulation: Arrhythmia and Electrophysiology | 2021 | 63 |
| 42 | Epstein-Barr Virus Induces Erosive Arthritis in Humanized Mice | PLoS ONE | 2011 | 62 |
| 43 | Humanized mice: A brief overview on their diverse applications in biomedical research | Journal of Cellular Physiology | 2018 | 59 |
| 44 | SARS-CoV-2 Disinfection of Air and Surface Contamination by TiO2 Photocatalyst-Mediated Damage to Viral Morphology, RNA, and Protein | Viruses | 2021 | 59 |
| 45 | Stabilization and Regression of Coronary Plaques Treated With Pitavastatin Proven by Angioscopy and Intravascular Ultrasound - The TOGETHAR Trial - | Circulation Journal | 2010 | 58 |
| 46 | Coronary vein infusion of multipotent stromal cells from bone marrow preserves cardiac function in swine ischemic cardiomyopathy via enhanced neovascularization | Laboratory Investigation | 2011 | 58 |
| 47 | Significance of Imbalance in the Ratio of Serum n-3 to n-6 Polyunsaturated Fatty Acids in Patients With Acute Coronary Syndrome | American Journal of Cardiology | 2014 | 58 |
| 48 | Clinical-Radiomic Analysis for Pretreatment Prediction of Objective Response to First Transarterial Chemoembolization in Hepatocellular Carcinoma | Liver Cancer | 2021 | 58 |
| 49 | Comparison of Sustained Hemodiafiltration With Continuous Venovenous Hemodiafiltration for the Treatment of Critically Ill Patients With Acute Kidney Injury | Artificial Organs | 2010 | 57 |
| 50 | Evaluation of an e-learning system for diagnosis of gastric lesions using magnifying narrow-band imaging: a multicenter randomized controlled study | Endoscopy | 2017 | 57 |
