| # | Title | Journal | Year | Citations |
|---|
| 1 | PTEN, a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer | Science | 1997 | 4,506 |
| 2 | The 2005 International Society of Urological Pathology (ISUP) Consensus Conference on Gleason Grading of Prostatic Carcinoma | American Journal of Surgical Pathology | 2005 | 2,334 |
| 3 | Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing | Cell | 2012 | 1,591 |
| 4 | Liver from bone marrow in humans | Hepatology | 2000 | 1,185 |
| 5 | Derivation of hepatocytes from bone marrow cells in mice after radiation-induced myeloablation | Hepatology | 2000 | 945 |
| 6 | Near real-time intraoperative brain tumor diagnosis using stimulated Raman histology and deep neural networks | Nature Medicine | 2020 | 413 |
| 7 | Rapid intraoperative histology of unprocessed surgical specimens via fibre-laser-based stimulated Raman scattering microscopy | Nature Biomedical Engineering | 2017 | 374 |
| 8 | Aristolochic acid-associated urothelial cancer in Taiwan | Proceedings of the National Academy of Sciences of the United States of America | 2012 | 347 |
| 9 | Potent Neuroprotective Properties against the Alzheimer β-Amyloid by an Endogenous Melatonin-related Indole Structure, Indole-3-propionic Acid | Journal of Biological Chemistry | 1999 | 317 |
| 10 | Hematopoietic Stem Cells Are the Major Source of Multilineage Hematopoiesis in Adult Animals | Immunity | 2016 | 317 |
| 11 | ORAI1 deficiency and lack of store-operated Ca2+ entry cause immunodeficiency, myopathy, and ectodermal dysplasia | Journal of Allergy and Clinical Immunology | 2009 | 289 |
| 12 | Whole-exome sequencing-based discovery of STIM1 deficiency in a child with fatal classic Kaposi sarcoma | Journal of Experimental Medicine | 2010 | 268 |
| 13 | Mechanism of STAT3 Activation by Insulin-like Growth Factor I Receptor | Journal of Biological Chemistry | 2000 | 221 |
| 14 | An empirical estimate of carrier frequencies for 400+ causal Mendelian variants: results from an ethnically diverse clinical sample of 23,453 individuals | Genetics in Medicine | 2013 | 220 |
| 15 | Pancreatic Cysts: Pathologic Classification, Differential Diagnosis, and Clinical Implications | Archives of Pathology and Laboratory Medicine | 2009 | 213 |
| 16 | Cleavage of Bax Enhances Its Cell Death Function | Experimental Cell Research | 2000 | 200 |
| 17 | CRAC channelopathies | Pflugers Archiv European Journal of Physiology | 2010 | 197 |
| 18 | The Repairability of Oxidative Free Radical Mediated Damage to DNA: A Review | International Journal of Radiation Biology | 1988 | 193 |
| 19 | Plasticity and Virus Specificity of the Airway Epithelial Cell Immune Response during Respiratory Virus Infection | Journal of Virology | 2012 | 176 |
| 20 | Polymorphous low-grade neuroepithelial tumor of the young (PLNTY): an epileptogenic neoplasm with oligodendroglioma-like components, aberrant CD34 expression, and genetic alterations involving the MAP kinase pathway | Acta Neuropathologica | 2017 | 172 |
| 21 | Podocyte cell cycle regulation and proliferation in collapsing glomerulopathies | Kidney International | 2000 | 171 |
| 22 | Clearance of amyloid β-peptide from brain: transport or metabolism? | Nature Medicine | 2000 | 171 |
| 23 | Immunohistochemical analysis of H3K27me3 demonstrates global reduction in group-A childhood posterior fossa ependymoma and is a powerful predictor of outcome | Acta Neuropathologica | 2017 | 168 |
| 24 | International investigation of breast MRI: results of a multicentre study (11 sites) concerning diagnostic parameters for contrast-enhanced MRI based on 519 histopathologically correlated lesions | European Radiology | 2001 | 163 |
| 25 | Dual mode of degradation of Cdc25 A phosphatase | EMBO Journal | 2002 | 163 |
| 26 | Immunodeficiency due to mutations in ORAI1 and STIM1 | Clinical Immunology | 2010 | 159 |
| 27 | Antiviral and Regulatory T Cell Immunity in a Patient with Stromal Interaction Molecule 1 Deficiency | Journal of Immunology | 2012 | 156 |
| 28 | Loss of integrated viral DNA sequences in polyoma-transformed cells is associated with an active viral A function | Cell | 1979 | 155 |
| 29 | STUDIES ON HYPERSENSITIVITY | Journal of Experimental Medicine | 1961 | 146 |
| 30 | Matrix Metalloproteinases in Abdominal Aortic Aneurysm: Characterization, Purification, And Their Possible Sources | Connective Tissue Research | 1994 | 142 |
| 31 | PHF6 mutations in adult acute myeloid leukemia | Leukemia | 2011 | 142 |
| 32 | Inhibition of cancer cell proliferation and prostaglandin E2 synthesis by Scutellaria baicalensis | Cancer Research | 2003 | 140 |
| 33 | MED12 and HMGA2 mutations: two independent genetic events in uterine leiomyoma and leiomyosarcoma | Modern Pathology | 2014 | 138 |
| 34 | Receptor for advanced glycation end products and its ligand high-mobility group box-1 mediate allergic airway sensitization and airway inflammation | Journal of Allergy and Clinical Immunology | 2014 | 133 |
| 35 | Mutant IDH1 and thrombosis in gliomas | Acta Neuropathologica | 2016 | 130 |
| 36 | Carcinoma of the Collecting Ducts of Bellini and Renal Medullary Carcinoma | American Journal of Surgical Pathology | 2012 | 127 |
| 37 | Extramedullary Plasmacytoma: A Form of Marginal Zone Cell Lymphoma? | American Journal of Clinical Pathology | 1999 | 125 |
| 38 | Suboptimal Activation of Antigen-Specific CD4+ Effector Cells Enables Persistence of M. tuberculosis In Vivo | PLoS Pathogens | 2011 | 125 |
| 39 | Fasciola hepatica: Parasite-Secreted Proteinases Degrade All Human IgG Subclasses: Determination of the Specific Cleavage Sites and Identification of the Immunoglobulin Fragments Produced | Experimental Parasitology | 2000 | 118 |
| 40 | Best Practices Recommendations in the Application of Immunohistochemistry in the Kidney Tumors | American Journal of Surgical Pathology | 2014 | 110 |
| 41 | Perivascular epithelioid cell tumor (PEComa) of the uterine cervix associated with intraabdominal "PEComatosis": A clinicopathological study with comparative genomic hybridization analysis | World Journal of Surgical Oncology | 2004 | 107 |
| 42 | Food group intake and risk of subtypes of esophageal and gastric cancer | International Journal of Cancer | 2008 | 106 |
| 43 | Karyotypic progression in human tumors | Cancer and Metastasis Reviews | 1983 | 105 |
| 44 | Regulation of lymphocyte function by ORAI and STIM proteins in infection and autoimmunity | Journal of Physiology | 2012 | 103 |
| 45 | Mitochondrial Oxidative Phosphorylation Regulates the Fate Decision between Pathogenic Th17 and Regulatory T Cells | Cell Reports | 2020 | 103 |
| 46 | TRANSCRIPTION OF PROTEIN- CODING GENES IN TRYPANOSOMES BY RNA POLYMERASE I | Annual Review of Microbiology | 1997 | 101 |
| 47 | Human Immunodeficiency Virus (HIV) Envelope Binds to CXCR4 Independently of CD4, and Binding Can Be Enhanced by Interaction with Soluble CD4 or by HIV Envelope Deglycosylation | Journal of Virology | 1998 | 101 |
| 48 | Periodontal pathogens are a risk factor of oral cavity squamous cell carcinoma, independent of tobacco and alcohol and human papillomavirus | International Journal of Cancer | 2019 | 101 |
| 49 | Knockdown of Stat3 activity in vivo prevents diabetic glomerulopathy | Kidney International | 2009 | 95 |
| 50 | The Pathology of Diverticulosis Coli | Journal of Clinical Gastroenterology | 2004 | 94 |
