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Top Articles

#TitleJournalYearCitations
1Proposed minimum reporting standards for chemical analysisMetabolomics20073,589
2The Henry reaction: recent examplesTetrahedron2001703
3The Metabolic Profile of Tumors Depends on Both the Responsible Genetic Lesion and Tissue TypeCell Metabolism2012553
4Representation of the molecular electrostatic potential by a net atomic charge modelJournal of Computational Chemistry1981514
5Altered regulation of metabolic pathways in human lung cancer discerned by 13C stable isotope-resolved metabolomics (SIRM)Molecular Cancer2009369
6Analysis of deuterium nuclear magnetic resonance line shapes in anisotropic mediaJournal of Chemical Physics1987341
7Crystal structure prediction of small organic molecules: a second blind testActa Crystallographica Section B: Structural Science2002334
8Ligand Effects and Ligand Design in Homogeneous Gold(I) CatalysisJournal of the American Chemical Society2012308
9Size-Dependent Electrochemical Oxidation of Silver NanoparticlesJournal of the American Chemical Society2010299
10Recent advances in the isolation and reactivity of organogold complexesChemical Society Reviews2012290
11Synthesis and Structural Characterization of Stable Organogold(I) Compounds. Evidence for the Mechanism of Gold-Catalyzed CyclizationsJournal of the American Chemical Society2008277
12The Synthesis and Fabrication of One-Dimensional Nanoscale HeterojunctionsSmall2007273
13Helix-stabilized cyclic peptides as selective inhibitors of steroid receptor-coactivator interactionsProceedings of the National Academy of Sciences of the United States of America2003206
14Tumor-derived exosomes drive immunosuppressive macrophages in a pre-metastatic niche through glycolytic dominant metabolic reprogrammingCell Metabolism2021200
15Evolution of Solvents in Organic ChemistryACS Sustainable Chemistry and Engineering2016199
16Calculation of the crystal structures of hydrocarbons by molecular packing analysisComputers & Chemistry1977192
17Recent synthetic additions to the visible light photoredox catalysis toolboxOrganic and Biomolecular Chemistry2015187
18Stable isotope-resolved metabolomics and applications for drug development2012186
19Nanoparticles in Measurement ScienceAnalytical Chemistry2012185
20Chronic Alcohol Exposure Stimulates Adipose Tissue Lipolysis in MiceAmerican Journal of Pathology2012183
21Aldehyde Detection in Electronic Cigarette AerosolsACS Omega2017181
22Probiotic Lactobacillus rhamnosus GG Prevents Liver Fibrosis Through Inhibiting Hepatic Bile Acid Synthesis and Enhancing Bile Acid Excretion in MiceHepatology2020178
23Structures and Solid-State Dynamics of One-Dimensional Water Chains Stabilized by Imidazole ChannelsAngewandte Chemie - International Edition2003177
24Designer HF-Based Fluorination Reagent: Highly Regioselective Synthesis of Fluoroalkenes and gem-Difluoromethylene Compounds from AlkynesJournal of the American Chemical Society2014169
25Representation of the molecular electrostatic potential by atomic multipole and bond dipole modelsJournal of Computational Chemistry1988167
26Intestinal HIF-1α deletion exacerbates alcoholic liver disease by inducing intestinal dysbiosis and barrier dysfunctionJournal of Hepatology2018160
27Multi-dimensional liquid chromatography in proteomics—A reviewAnalytica Chimica Acta2010158
28Exacerbation of diabetes-induced testicular apoptosis by zinc deficiency is most likely associated with oxidative stress, p38 MAPK activation, and p53 activation in miceToxicology Letters2011158
29Fully Integrated On-Chip Electrochemical Detection for Capillary Electrophoresis in a Microfabricated DeviceAnalytical Chemistry2002156
30Fluorine‐Enabled Cationic Gold Catalysis: Functionalized Hydration of AlkynesAngewandte Chemie - International Edition2010144
31Resolution and characterization of the structural polymorphism of a single quadruplex-forming sequenceNucleic Acids Research2010141
32In Situ MALDI-TOF MS Regional Analysis of Neutral Phospholipids in Lens TissueAnalytical Chemistry2004135
33Surface properties of SnO2 nanowires for enhanced performance with dye-sensitized solar cellsEnergy and Environmental Science2009131
34Optimization of Catalysts and Conditions in Gold(I) Catalysis—Counterion and Additive EffectsChemical Reviews2021131
35Improved intermolecular force field for molecules containing H, C, N, and O atoms, with application to nucleoside and peptide crystalsJournal of Computational Chemistry2001129
36Lipid-mediated delivery of RNA is more efficient than delivery of DNA in non-dividing cellsInternational Journal of Pharmaceutics2010129
37Dectin-1 Activation by a Natural Product β-Glucan Converts Immunosuppressive Macrophages into an M1-like PhenotypeJournal of Immunology2015129
38Lipids and the ocular lensJournal of Lipid Research2010128
39Chemiresistive Sensing with Chemically Modified Metal and Alloy NanoparticlesSmall2012127
40Chemically modified electrodes in liquid chromatography detection: A reviewTalanta1991120
41Chemically modified carbon paste electrodesJournal of Electroanalytical Chemistry and Interfacial Electrochemistry1981117
42Alternative approaches for the detection of various phospholipid classes by matrix-assisted laser desorption/ionization time-of-flight mass spectrometryJournal of Mass Spectrometry2004114
43Detection of pesticides using an amperometric biosensor based on ferophthalocyanine chemically modified carbon paste electrode and immobilized bienzymatic systemBiosensors and Bioelectronics2003112
44Performance of DFT in modeling electronic and structural properties of cobalaminsJournal of Computational Chemistry2006111
45Determination of carbohydrates, sugar acids and alditols by capillary electrophoresis and electrochemical detection at a copper electrodeJournal of Chromatography A1994110
46Synthesis, Cytotoxicity, and Anti-Trypanosoma cruzi Activity of New ChalconesJournal of Medicinal Chemistry2008110
47Isotopomer‐Based Metabolomic Analysis by NMR and Mass SpectrometryMethods in Cell Biology2008109
48Hydrogen Reactivity of Palladium Nanoparticles Coated with Mixed Monolayers of Alkyl Thiols and Alkyl Amines for Sensing and Catalysis ApplicationsJournal of the American Chemical Society2011107
49Noninvasive detection of lung cancer using exhaled breathCancer Medicine2014105
50Quantitative Observation of Backbone Disorder in Native ElastinJournal of Biological Chemistry2004104