| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | The CYP2D6 Activity Score: Translating Genotype Information into a Qualitative Measure of Phenotype | Clinical Pharmacology and Therapeutics | 2008 | 650 |
| 3 | A recurrent 16p12.1 microdeletion supports a two-hit model for severe developmental delay | Nature Genetics | 2010 | 539 |
| 4 | MicroRNAs in NF- B signaling | Journal of Molecular Cell Biology | 2011 | 530 |
| 5 | TLR-signaling Networks | Journal of Dental Research | 2011 | 472 |
| 6 | Estrogen receptor interaction with co-activators and co-repressors☆ | Steroids | 2000 | 413 |
| 7 | Acute hyperglycemia and the innate immune system: Clinical, cellular, and molecular aspects | Critical Care Medicine | 2005 | 405 |
| 8 | Probiotics restore bowel flora and improve liver enzymes in human alcohol-induced liver injury: a pilot study | Alcohol | 2008 | 398 |
| 9 | Comparison of the Safety of Early Enteral vs Parenteral Nutrition in Mild Acute Pancreatitis | Journal of Parenteral and Enteral Nutrition | 1997 | 376 |
| 10 | Body Fat and the Activity of the Autonomic Nervous System | New England Journal of Medicine | 1988 | 373 |
| 11 | The Presence of Gonadotropin Receptors in Nonpregnant Human Uterus, Human Placenta, Fetal Membranes, and Decidua* | Journal of Clinical Endocrinology and Metabolism | 1990 | 363 |
| 12 | Mechanism of Oxidative Stress and Synapse Dysfunction in the Pathogenesis of Alzheimer’s Disease: Understanding the Therapeutics Strategies | Molecular Neurobiology | 2016 | 352 |
| 13 | Impact of Symptom Prevalence and Symptom Burden on Quality of Life in Patients with Heart Failure | European Journal of Cardiovascular Nursing | 2005 | 348 |
| 14 | Pachytene piRNAs instruct massive mRNA elimination during late spermiogenesis | Cell Research | 2014 | 344 |
| 15 | Nuclear factor-kappa B signaling in skeletal muscle atrophy | Journal of Molecular Medicine | 2008 | 338 |
| 16 | Mechanisms of homocysteine-induced oxidative stress | American Journal of Physiology - Heart and Circulatory Physiology | 2005 | 327 |
| 17 | Safety and Efficacy of Microwave Ablation of Hepatic Tumors: A Prospective Review of a 5-Year Experience | Annals of Surgical Oncology | 2010 | 322 |
| 18 | Uric acid: A new look at an old risk marker for cardiovascular disease, metabolic syndrome, and type 2 diabetes mellitus: The urate redox shuttle | Nutrition and Metabolism | 2004 | 310 |
| 19 | Monocyte HLA-DR antigen expression characterizes clinical outcome in the trauma patient | British Journal of Surgery | 2005 | 310 |
| 20 | A novel miR-155/miR-143 cascade controls glycolysis by regulatinghexokinase 2in breast cancer cells | EMBO Journal | 2012 | 309 |
| 21 | Generation of Oligodendrocyte Precursor Cells from Mouse Dorsal Spinal Cord Independent of Nkx6 Regulation and Shh Signaling | Neuron | 2005 | 305 |
| 22 | HPV vaccines – A review of the first decade | Gynecologic Oncology | 2017 | 304 |
| 23 | Control of oligodendrocyte differentiation by theNkx2.2homeodomain transcription factor | Development (Cambridge) | 2001 | 303 |
| 24 | Taxonomy of the order Bunyavirales: update 2019 | Archives of Virology | 2019 | 285 |
| 25 | Exosomes: Mediators of Neurodegeneration, Neuroprotection and Therapeutics | Molecular Neurobiology | 2014 | 281 |
| 26 | Charting a future for epidemiologic training | Annals of Epidemiology | 2015 | 280 |
| 27 | Chondroitinase ABC Digestion of the Perineuronal Net Promotes Functional Collateral Sprouting in the Cuneate Nucleus after Cervical Spinal Cord Injury | Journal of Neuroscience | 2006 | 276 |
| 28 | Steroid-hormone receptors in breast cancer | Cancer | 1984 | 275 |
| 29 | Cretaceous eutherians and Laurasian origin for placental mammals near the K/T boundary | Nature | 2007 | 262 |
| 30 | Prehistoric genomes reveal the genetic foundation and cost of horse domestication | Proceedings of the National Academy of Sciences of the United States of America | 2014 | 260 |
| 31 | Mechanisms of Molecular Mimicry Involving the Microbiota in Neurodegeneration | Journal of Alzheimer's Disease | 2015 | 259 |
| 32 | Doxorubicin and Paclitaxel-Loaded Lipid-Based Nanoparticles Overcome Multidrug Resistance by Inhibiting P-Glycoprotein and Depleting ATP | Cancer Research | 2009 | 257 |
| 33 | Bruising Characteristics Discriminating Physical Child Abuse From Accidental Trauma | Pediatrics | 2010 | 255 |
| 34 | Negative regulation of the tumor suppressor p53 gene by microRNAs | Oncogene | 2011 | 255 |
| 35 | Novel role of human chorionic gonadotropin in differentiation of human cytotrophoblasts. | Endocrinology | 1993 | 250 |
| 36 | Implications of Deltatheridium specimens for early marsupial history | Nature | 1998 | 240 |
| 37 | Integrin α2β1 mediates outside-in regulation of platelet spreading on collagen through activation of Src kinases and PLCγ2 | Journal of Cell Biology | 2003 | 231 |
| 38 | Nrf2 is critical in defense against high glucose-induced oxidative damage in cardiomyocytes | Journal of Molecular and Cellular Cardiology | 2009 | 225 |
| 39 | Contribution of the hydrophobic effect to microbial infection | Microbes and Infection | 2000 | 220 |
| 40 | Oral Magnesium Oxide Prophylaxis of Frequent Migrainous Headache in Children: A Randomized, Double-Blind, Placebo-Controlled Trial | Headache | 2003 | 207 |
| 41 | Epithelial-Mesenchymal Transition and Proliferation of Retinal Pigment Epithelial Cells Initiated upon Loss of Cell-Cell Contact | Headache | 2010 | 204 |
| 42 | miR-301a as an NF-κB activator in pancreatic cancer cells | EMBO Journal | 2011 | 204 |
| 43 | Oxidative and nitrative stress in neurodegeneration | Neurobiology of Disease | 2015 | 204 |
| 44 | Articular step-off and risk of post-traumatic osteoarthritis. Evidence today | Injury | 2010 | 202 |
| 45 | Loss of the miR-21 allele elevates the expression of its target genes and reduces tumorigenesis | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 202 |
| 46 | Curcumin-loaded embryonic stem cell exosomes restored neurovascular unit following ischemia-reperfusion injury | International Journal of Biochemistry and Cell Biology | 2016 | 200 |
| 47 | Tumor-derived exosomes drive immunosuppressive macrophages in a pre-metastatic niche through glycolytic dominant metabolic reprogramming | Cell Metabolism | 2021 | 200 |
| 48 | Quantitative Cell Composition of Human and Bovine Corpora Lutea from Various Reproductive States1 | Biology of Reproduction | 1991 | 198 |
| 49 | Tube Thoracostomy | Archives of Surgery | 1995 | 198 |
| 50 | Physiologic and other effects and compliance with long-term respirator use among medical intensive care unit nurses | American Journal of Infection Control | 2013 | 198 |
