| # | Title | Journal | Year | Citations |
|---|
| 1 | Isoflavones: estrogenic activity, biological effect and bioavailability | European Journal of Drug Metabolism and Pharmacokinetics | 2013 | 360 |
| 2 | Role of Omega-3 Fatty Acids in the Treatment of Depressive Disorders: A Comprehensive Meta-Analysis of Randomized Clinical Trials | PLoS ONE | 2014 | 358 |
| 3 | A comprehensive meta-analysis on evidence of Mediterranean diet and cardiovascular disease: Are individual components equal? | Critical Reviews in Food Science and Nutrition | 2017 | 325 |
| 4 | New pharmacological strategies for treatment of Alzheimer's disease: focus on disease modifying drugs | British Journal of Clinical Pharmacology | 2012 | 253 |
| 5 | Omega-3 Fatty Acids and Depression: Scientific Evidence and Biological Mechanisms | Oxidative Medicine and Cellular Longevity | 2014 | 215 |
| 6 | A review of recent evidence in human studies of n-3 and n-6 PUFA intake on cardiovascular disease, cancer, and depressive disorders: does the ratio really matter? | International Journal of Food Sciences and Nutrition | 2015 | 186 |
| 7 | Antioxidants as Antidepressants | CNS Drugs | 2012 | 144 |
| 8 | Coffee, tea, caffeine and risk of depression: A systematic review and dose–response meta‐analysis of observational studies | Molecular Nutrition and Food Research | 2016 | 143 |
| 9 | Clinically Significant Drug Interactions with Newer Antidepressants | CNS Drugs | 2012 | 135 |
| 10 | Factors Associated with Adherence to the Mediterranean Diet among Adolescents Living in Sicily, Southern Italy | Nutrients | 2013 | 127 |
| 11 | Eriodictyol prevents early retinal and plasma abnormalities in streptozotocin-induced diabetic rats | Biochemical Pharmacology | 2012 | 126 |
| 12 | Stress and corticosterone increase the readily releasable pool of glutamate vesicles in synaptic terminals of prefrontal and frontal cortex | Molecular Psychiatry | 2014 | 125 |
| 13 | Legume consumption and CVD risk: a systematic review and meta-analysis | Public Health Nutrition | 2017 | 118 |
| 14 | Dopamine D3 receptor as a new pharmacological target for the treatment of depression | European Journal of Pharmacology | 2013 | 115 |
| 15 | Association of daily coffee and tea consumption and metabolic syndrome: results from the Polish arm of the HAPIEE study | European Journal of Nutrition | 2015 | 100 |
| 16 | Red Orange: Experimental Models and Epidemiological Evidence of Its Benefits on Human Health | Oxidative Medicine and Cellular Longevity | 2013 | 97 |
| 17 | Dysfunction of TGF-β1 signaling in Alzheimer’s disease: perspectives for neuroprotection | Cell and Tissue Research | 2012 | 96 |
| 18 | Ocular drug delivery: a clue from nanotechnology | Frontiers in Pharmacology | 2012 | 94 |
| 19 | Sleep quality and duration is related with diet and obesity in young adolescent living in Sicily, Southern Italy | Sleep Science | 2016 | 86 |
| 20 | Evaluation of CHI3L-1 and CHIT-1 Expression in Differentiated and Polarized Macrophages | Inflammation | 2013 | 81 |
| 21 | Astroglial type-1 cannabinoid receptor (CB1): A new player in the tripartite synapse | Neuroscience | 2016 | 74 |
| 22 | Influence of different surfactants on the technological properties and in vivo ocular tolerability of lipid nanoparticles | International Journal of Pharmaceutics | 2014 | 72 |
| 23 | Cationic solid lipid nanoparticles enhance ocular hypotensive effect of melatonin in rabbit | International Journal of Pharmaceutics | 2015 | 71 |
| 24 | Role of phospholipases A2 in diabetic retinopathy: In vitro and in vivo studies | Biochemical Pharmacology | 2013 | 67 |
| 25 | Laparoscopic vs. open approach for colorectal cancer: evolution over time of minimal invasive surgery | BMC Surgery | 2013 | 66 |
| 26 | Pharmacological management of ocular hypertension: current approaches and future prospective | Current Opinion in Pharmacology | 2013 | 66 |
| 27 | Evaluation of four comorbidity indices and Charlson comorbidity index adjustment for colorectal cancer patients | International Journal of Colorectal Disease | 2014 | 66 |
| 28 | Neutralization of TNFSF10 ameliorates functional outcome in a murine model of Alzheimer’s disease | Brain | 2015 | 62 |
| 29 | Homology Modeling of Dopamine D2 and D3 Receptors: Molecular Dynamics Refinement and Docking Evaluation | PLoS ONE | 2012 | 62 |
| 30 | Low levels of 17-β-oestradiol, oestrone and testosterone correlate with severe evaporative dysfunctional tear syndrome in postmenopausal women: a case–control study | British Journal of Ophthalmology | 2014 | 58 |
| 31 | Factors Associated with Colorectal Cancer in the Context of the Mediterranean Diet: A Case-Control Study | Nutrition and Cancer | 2014 | 53 |
| 32 | Protective role of the Mediterranean diet on several cardiovascular risk factors: Evidence from Sicily, southern Italy | Nutrition, Metabolism and Cardiovascular Diseases | 2014 | 53 |
| 33 | Dopamine D3 Receptor Is Necessary for Ethanol Consumption: An Approach with Buspirone | Neuropsychopharmacology | 2014 | 52 |
| 34 | PACAP and VIP increase the expression of myelin-related proteins in rat schwannoma cells: Involvement of PAC1/VPAC2 receptor-mediated activation of PI3K/Akt signaling pathways | Experimental Cell Research | 2014 | 49 |
| 35 | The predictive value of ABCB1, ABCG2, CYP3A4/5 and CYP2D6 polymorphisms for risperidone and aripiprazole plasma concentrations and the occurrence of adverse drug reactions | Pharmacogenomics Journal | 2018 | 47 |
| 36 | Protecting the retinal neurons from glaucoma: Lowering ocular pressure is not enough | Pharmacological Research | 2012 | 45 |
| 37 | The selective norepinephrine reuptake inhibitor atomoxetine counteracts behavioral impairments in trimethyltin-intoxicated rats | European Journal of Pharmacology | 2012 | 39 |
| 38 | Fortified Extract of Red Berry,Ginkgo biloba, and White Willow Bark in Experimental Early Diabetic Retinopathy | Journal of Diabetes Research | 2013 | 39 |
| 39 | GIRK channel modulation by assembly with allosterically regulated RGS proteins | Proceedings of the National Academy of Sciences of the United States of America | 2012 | 38 |
| 40 | POOLED ESTIMATES OF INCIDENCE OF ENDOPHTHALMITIS AFTER INTRAVITREAL INJECTION OF ANTI–VASCULAR ENDOTHELIAL GROWTH FACTOR AGENTS WITH AND WITHOUT TOPICAL ANTIBIOTIC PROPHYLAXIS | Retina | 2018 | 37 |
| 41 | Antiproliferative Effects of PACAP and VIP in Serum-Starved Glioma Cells | Journal of Molecular Neuroscience | 2013 | 34 |
| 42 | Increasing the Coding Potential of Genomes Through Alternative Splicing: The Case of PARK2 Gene | Current Genomics | 2014 | 32 |
| 43 | Antioxidant vitamin intake and mortality in three Central and Eastern European urban populations: the HAPIEE study | European Journal of Nutrition | 2016 | 32 |
| 44 | Davunetide (NAP) Protects the Retina Against Early Diabetic Injury by Reducing Apoptotic Death | Journal of Molecular Neuroscience | 2014 | 31 |
| 45 | Expression profile of parkin isoforms in human gliomas | International Journal of Oncology | 2015 | 29 |
| 46 | Dopamine-3 receptor modulates intraocular pressure: Implications for glaucoma | Biochemical Pharmacology | 2012 | 28 |
| 47 | Protocatechuic Acid Prevents oxLDL-Induced Apoptosis by Activating JNK/Nrf2 Survival Signals in Macrophages | Oxidative Medicine and Cellular Longevity | 2015 | 28 |
| 48 | Dopamine D3 receptor-dependent changes in alpha6 GABAA subunit expression in striatum modulate anxiety-like behaviour: Responsiveness and tolerance to diazepam | European Neuropsychopharmacology | 2015 | 28 |
| 49 | Ischemic tolerance modulates TRAIL expression and its receptors and generates a neuroprotected phenotype | Cell Death and Disease | 2014 | 27 |
| 50 | NAP Reduces Murine Microvascular Endothelial Cells Proliferation Induced by Hyperglycemia | Journal of Molecular Neuroscience | 2014 | 25 |
