| # | Title | Journal | Year | Citations |
|---|
| 1 | Effects of Genistein and Hormone-Replacement Therapy on Bone Loss in Early Postmenopausal Women: A Randomized Double-Blind Placebo-Controlled Study | Journal of Bone and Mineral Research | 2002 | 371 |
| 2 | Cellular stress responses, hormetic phytochemicals and vitagenes in aging and longevity | Biochimica Et Biophysica Acta - Molecular Basis of Disease | 2012 | 351 |
| 3 | Antiinflammatory Activity of Melatonin in Central Nervous System | Current Neuropharmacology | 2010 | 325 |
| 4 | Influence of CYP2C9 and CYP2C19 genetic polymorphisms on warfarin maintenance dose and metabolic clearance | Clinical Pharmacology and Therapeutics | 2002 | 322 |
| 5 | Clinically relevant pharmacokinetic drug interactions with second-generation antidepressants: An update | Clinical Therapeutics | 2008 | 312 |
| 6 | Traumatic Brain Injury: Oxidative Stress and Neuroprotection | Antioxidants and Redox Signaling | 2013 | 261 |
| 7 | Epidemiology of gout and hyperuricaemia in Italy during the years 2005–2009: a nationwide population-based study | Annals of the Rheumatic Diseases | 2013 | 231 |
| 8 | Metabolic Drug Interactions with Newer Antipsychotics: A Comparative Review | Basic and Clinical Pharmacology and Toxicology | 2007 | 223 |
| 9 | The effect of the phytoestrogen genistein on plasma nitric oxide concentrations, endothelin-1 levels and endothelium dependent vasodilation in postmenopausal women | Atherosclerosis | 2002 | 211 |
| 10 | Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-γ, reduces acute inflammation | European Journal of Pharmacology | 2004 | 198 |
| 11 | Sertindole: pharmacological and clinical profile and role in the treatment of schizophrenia | Expert Opinion on Drug Metabolism and Toxicology | 2008 | 180 |
| 12 | Recombinant Human Erythropoietin Stimulates Angiogenesis and Wound Healing in the Genetically Diabetic Mouse | Diabetes | 2004 | 174 |
| 13 | Antiepileptic drugs: indications other than epilepsy | Epileptic Disorders | 2004 | 167 |
| 14 | Data mining on electronic health record databases for signal detection in pharmacovigilance: which events to monitor? | Pharmacoepidemiology and Drug Safety | 2009 | 162 |
| 15 | Recombinant human erythropoietin improves angiogenesis and wound healing in experimental burn wounds* | Critical Care Medicine | 2006 | 157 |
| 16 | Reactive Oxygen Species, Inflammation, and Lung Diseases | Current Pharmaceutical Design | 2012 | 157 |
| 17 | Metabolic drug interactions with new psychotropic agents | Fundamental and Clinical Pharmacology | 2003 | 152 |
| 18 | Effect of genistein on endothelial function in postmenopausal women: a randomized, double-blind, controlled study | American Journal of Medicine | 2003 | 151 |
| 19 | Neuroprotective Activities of Palmitoylethanolamide in an Animal Model of Parkinson's Disease | PLoS ONE | 2012 | 145 |
| 20 | Breast Safety and Efficacy of Genistein Aglycone for Postmenopausal Bone Loss: A Follow-Up Study | Journal of Clinical Endocrinology and Metabolism | 2008 | 142 |
| 21 | Effect of rosiglitazone and 15-deoxy- 12,14-prostaglandin J2 on bleomycin-induced lung injury | European Respiratory Journal | 2005 | 140 |
| 22 | Inhibition of nitric oxide biosynthesis by anthocyanin fraction of blackberry extract | Nitric Oxide - Biology and Chemistry | 2006 | 140 |
| 23 | Potential Therapeutic Effect of Antioxidant Therapy in Shock and Inflammation | Current Medicinal Chemistry | 2004 | 138 |
| 24 | Intake of Energy Drinks in Association With Alcoholic Beverages in a Cohort of Students of the School of Medicine of the University of Messina | Alcoholism: Clinical and Experimental Research | 2007 | 138 |
| 25 | Immunomodulatory Effects of Etanercept in an Experimental Model of Spinal Cord Injury | Journal of Pharmacology and Experimental Therapeutics | 2006 | 136 |
| 26 | Clinically Significant Drug Interactions with Newer Antidepressants | CNS Drugs | 2012 | 135 |
| 27 | Recombinant AAV vector encoding human VEGF165 enhances wound healing | Gene Therapy | 2002 | 123 |
| 28 | The Development and Maintenance of Paclitaxel-induced Neuropathic Pain Require Activation of the Sphingosine 1-Phosphate Receptor Subtype 1 | Journal of Biological Chemistry | 2014 | 123 |
| 29 | Glucocorticoid-Induced Leucine Zipper Is Protective in Th1-Mediated Models of Colitis | Gastroenterology | 2009 | 122 |
| 30 | Clinically Significant Drug Interactions with Antidepressants in the Elderly | Drugs and Aging | 2002 | 120 |
| 31 | Cranberry and Recurrent Cystitis: More than Marketing? | Critical Reviews in Food Science and Nutrition | 2014 | 118 |
| 32 | Simvastatin enhances VEGF production and ameliorates impaired wound healing in experimental diabetes | Pharmacological Research | 2008 | 117 |
| 33 | ROLE OF TUMOR NECROSIS FACTOR-α IN ACUTE PANCREATITIS | Shock | 2007 | 114 |
| 34 | Role of TNF-α in lung tight junction alteration in mouse model of acute lung inflammation | Respiratory Research | 2007 | 114 |
| 35 | Adrenocorticotropin reverses hemorrhagic shock in anesthetized rats through the rapid activation of a vagal anti-inflammatory pathway | Cardiovascular Research | 2004 | 113 |
| 36 | Molecular mechanisms involved in the reciprocal regulation of cyclooxygenase and nitric oxide synthase enzymes | Kidney International | 2007 | 107 |
| 37 | Plasma Concentrations of Risperidone and 9-Hydroxyrisperidone During Combined Treatment With Paroxetine | Therapeutic Drug Monitoring | 2001 | 106 |
| 38 | Inhibition of Risperidone Metabolism by Fluoxetine in Patients With Schizophrenia: A Clinically Relevant Pharmacokinetic Drug Interaction | Journal of Clinical Psychopharmacology | 2002 | 103 |
| 39 | Effects of genistein on hot flushes in early postmenopausal women: a randomized, double-blind EPT- and placebo-controlled study. | Menopause | 2004 | 102 |
| 40 | Anti-TNF therapy in the injured spinal cord | Trends in Pharmacological Sciences | 2011 | 102 |
| 41 | Glycyrrhizin attenuates the development of carrageenan-induced lung injury in mice | Pharmacological Research | 2008 | 101 |
| 42 | Flavocoxid, a dual inhibitor of cyclooxygenase and 5‐lipoxygenase, blunts pro‐inflammatory phenotype activation in endotoxin‐stimulated macrophages | British Journal of Pharmacology | 2009 | 100 |
| 43 | Attenuation in the evolution of experimental spinal cord trauma by treatment with melatonin | Journal of Pineal Research | 2005 | 98 |
| 44 | Effects of palmitoylethanolamide on release of mast cell peptidases and neurotrophic factors after spinal cord injury | Brain, Behavior, and Immunity | 2011 | 97 |
| 45 | Influence of CYP2C9, 2C19 and 2D6 Genetic Polymorphisms on the Steady-State Plasma Concentrations of the Enantiomers of Fluoxetine and Norfluoxetine | Basic and Clinical Pharmacology and Toxicology | 2005 | 94 |
| 46 | The effect of lamotrigine augmentation of clozapine in a sample of treatment-resistant schizophrenic patients: A double-blind, placebo-controlled study | Schizophrenia Research | 2007 | 93 |
| 47 | Use of antipsychotics in elderly patients with dementia: Do atypical and conventional agents have a similar safety profile? | Pharmacological Research | 2009 | 93 |
| 48 | Oxidative Stress as the Leading Cause of Acute Myocardial Infarction in Diabetics | Cardiovascular Drug Reviews | 2006 | 92 |
| 49 | Adverse drug reactions related to amoxicillin alone and in association with clavulanic acid: data from spontaneous reporting in Italy | Journal of Antimicrobial Chemotherapy | 2007 | 92 |
| 50 | ACTIVATION OF THE CHOLINERGIC ANTI-INFLAMMATORY PATHWAY REDUCES NF-κB ACTIVATION, BLUNTS TNF-α PRODUCTION, AND PROTECTS AGAINTS SPLANCHIC ARTERY OCCLUSION SHOCK | Shock | 2006 | 91 |
