| # | Title | Journal | Year | Citations |
|---|
| 1 | Chemical genetics of Plasmodium falciparum | Nature | 2010 | 515 |
| 2 | The Anti-Cancer Effect of Quercetin: Molecular Implications in Cancer Metabolism | International Journal of Molecular Sciences | 2019 | 361 |
| 3 | A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria | Science Translational Medicine | 2015 | 254 |
| 4 | Doxorubicin resistance in breast cancer cells is mediated by extracellular matrix proteins | BMC Cancer | 2018 | 234 |
| 5 | Advanced Cell Culture Techniques for Cancer Drug Discovery | Biology | 2014 | 210 |
| 6 | Leishmaniasis drug discovery: recent progress and challenges in assay development | Drug Discovery Today | 2017 | 145 |
| 7 | Identification of inhibitors of Plasmodium falciparum gametocyte development | Malaria Journal | 2013 | 130 |
| 8 | Screening the Medicines for Malaria Venture Pathogen Box across Multiple Pathogens Reclassifies Starting Points for Open-Source Drug Discovery | Antimicrobial Agents and Chemotherapy | 2017 | 106 |
| 9 | HBO1 is required for the maintenance of leukaemia stem cells | Nature | 2020 | 105 |
| 10 | Identification of MMV Malaria Box Inhibitors of Plasmodium falciparum Early-Stage Gametocytes Using a Luciferase-Based High-Throughput Assay | Antimicrobial Agents and Chemotherapy | 2013 | 102 |
| 11 | Identification of Compounds with Anti-Proliferative Activity against Trypanosoma brucei brucei Strain 427 by a Whole Cell Viability Based HTS Campaign | PLoS Neglected Tropical Diseases | 2012 | 77 |
| 12 | Approaches to Protozoan Drug Discovery: Phenotypic Screening | Journal of Medicinal Chemistry | 2013 | 70 |
| 13 | Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles | ACS Central Science | 2016 | 68 |
| 14 | Evaluation of chemotherapeutics in a three-dimensional breast cancer model | Journal of Cancer Research and Clinical Oncology | 2015 | 67 |
| 15 | Luciferase-Based, High-Throughput Assay for Screening and Profiling Transmission-Blocking Compounds against Plasmodium falciparum Gametocytes | Antimicrobial Agents and Chemotherapy | 2016 | 62 |
| 16 | Screening a Natural Product-Based Library against Kinetoplastid Parasites | Molecules | 2017 | 53 |
| 17 | Miniaturized Three-Dimensional Cancer Model for Drug Evaluation | Assay and Drug Development Technologies | 2013 | 52 |
| 18 | Two-Pronged Attack: Dual Inhibition of Plasmodium falciparum M1 and M17 Metalloaminopeptidases by a Novel Series of Hydroxamic Acid-Based Inhibitors | Journal of Medicinal Chemistry | 2014 | 52 |
| 19 | Large-scale production of Plasmodium falciparum gametocytes for malaria drug discovery | Nature Protocols | 2016 | 49 |
| 20 | The cubane paradigm in bioactive molecule discovery: further scope, limitations and the cyclooctatetraene complement | Organic and Biomolecular Chemistry | 2019 | 49 |
| 21 | Screening and hit evaluation of a chemical library against blood-stage Plasmodium falciparum | Malaria Journal | 2014 | 47 |
| 22 | Hexahydroquinolines are antimalarial candidates with potent blood-stage and transmission-blocking activity | Nature Microbiology | 2017 | 47 |
| 23 | A simple and predictive phenotypic High Content Imaging assay for Plasmodium falciparum mature gametocytes to identify malaria transmission blocking compounds | Scientific Reports | 2015 | 46 |
| 24 | Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions | European Journal of Medicinal Chemistry | 2016 | 46 |
| 25 | Histone Methyltransferase Inhibitors Are Orally Bioavailable, Fast-Acting Molecules with Activity against Different Species Causing Malaria in Humans | Antimicrobial Agents and Chemotherapy | 2015 | 43 |
| 26 | Optimization of 2-Anilino 4-Amino Substituted Quinazolines into Potent Antimalarial Agents with Oral in Vivo Activity | Journal of Medicinal Chemistry | 2017 | 43 |
| 27 | Development and application of a sensitive, phenotypic, high-throughput image-based assay to identify compound activity against Trypanosoma cruzi amastigotes | International Journal for Parasitology: Drugs and Drug Resistance | 2015 | 39 |
| 28 | N-Aryl-2-aminobenzimidazoles: Novel, Efficacious, Antimalarial Lead Compounds | Journal of Medicinal Chemistry | 2014 | 37 |
| 29 | Repositioning: the fast track to new anti-malarial medicines? | Malaria Journal | 2014 | 36 |
| 30 | The synthesis, antimalarial activity and CoMFA analysis of novel aminoalkylated quercetin analogs | Bioorganic and Medicinal Chemistry Letters | 2015 | 36 |
| 31 | Dexmedetomidine Improves Cardiovascular and Ventilatory Outcomes in Critically Ill Patients: Basic and Clinical Approaches | Frontiers in Pharmacology | 2019 | 36 |
| 32 | Copper, Nickel, and Zinc Cyclam–Amino Acid and Cyclam–Peptide Complexes May Be Synthesized with “Click” Chemistry and Are Noncytotoxic | Inorganic Chemistry | 2011 | 35 |
| 33 | Whole-cell in vitro screening for gametocytocidal compounds | Future Medicinal Chemistry | 2012 | 35 |
| 34 | A novel approach for the discovery of chemically diverse anti-malarial compounds targeting the Plasmodium falciparum Coenzyme A synthesis pathway | Malaria Journal | 2014 | 34 |
| 35 | Bone-stromal cells up-regulate tumourigenic markers in a tumour-stromal 3D model of prostate cancer | Molecular Cancer | 2013 | 33 |
| 36 | Rotenoids, Flavonoids, and Chalcones from the Root Bark of Millettia usaramensis | Journal of Natural Products | 2015 | 33 |
| 37 | Hydroxamic Acid Inhibitors Provide Cross-Species Inhibition of Plasmodium M1 and M17 Aminopeptidases | Journal of Medicinal Chemistry | 2019 | 30 |
| 38 | Antimalarial activity of natural product extracts from Papua New Guinean and Australian plants against Plasmodium falciparum | Phytotherapy Research | 2008 | 28 |
| 39 | Metabolomics and lipidomics reveal perturbation of sphingolipid metabolism by a novel anti-trypanosomal 3-(oxazolo[4,5-b]pyridine-2-yl)anilide | Metabolomics | 2016 | 28 |
| 40 | Organometallic Conjugates of the Drug Sulfadoxine for Combatting Antimicrobial Resistance | Chemistry - A European Journal | 2018 | 28 |
| 41 | Polyoxygenated Cyclohexenes and Other Constituents of Cleistochlamys kirkii Leaves | Journal of Natural Products | 2017 | 27 |
| 42 | Orthoscuticellines A–E, β-Carboline Alkaloids from the Bryozoan Orthoscuticella ventricosa Collected in Australia | Journal of Natural Products | 2020 | 27 |
| 43 | Watsonianone A–C, anti-plasmodial β-triketones from the Australian tree, Corymbia watsoniana | Organic and Biomolecular Chemistry | 2013 | 26 |
| 44 | Inhibition of Plasmepsin V Activity Blocks Plasmodium falciparum Gametocytogenesis and Transmission to Mosquitoes | Cell Reports | 2019 | 25 |
| 45 | A Plasmodium vivax experimental human infection model for evaluating efficacy of interventions | Journal of Clinical Investigation | 2020 | 25 |
| 46 | Antimalarial 3-arylamino-6-benzylamino-1,2,4,5-tetrazines | Bioorganic and Medicinal Chemistry Letters | 2010 | 24 |
| 47 | Aminoazabenzimidazoles, a Novel Class of Orally Active Antimalarial Agents | Journal of Medicinal Chemistry | 2014 | 24 |
| 48 | An evaluation of Minor Groove Binders as anti- Trypanosoma brucei brucei therapeutics | European Journal of Medicinal Chemistry | 2016 | 24 |
| 49 | Plasmodium falciparum in vitro continuous culture conditions: A comparison of parasite susceptibility and tolerance to anti-malarial drugs throughout the asexual intra-erythrocytic life cycle | International Journal for Parasitology: Drugs and Drug Resistance | 2017 | 24 |
| 50 | Mechanisms of Cardiovascular Protection Associated with Intermittent Hypobaric Hypoxia Exposure in a Rat Model: Role of Oxidative Stress | International Journal of Molecular Sciences | 2018 | 24 |
