| # | Title | Journal | Year | Citations |
|---|
| 1 | Effect of Metformin and Rosiglitazone Combination Therapy in Patients With Type 2 Diabetes Mellitus | JAMA - Journal of the American Medical Association | 2000 | 476 |
| 2 | A two-site monoclonal antibody ELISA for the quantification of the major Dermatophagoides spp. allergens, Der p I and Der f I | Journal of Immunological Methods | 1989 | 390 |
| 3 | Mutations in the pre-core region of hepatitis B virus serve to enhance the stability of the secondary structure of the pre-genome encapsidation signal. | Proceedings of the National Academy of Sciences of the United States of America | 1994 | 364 |
| 4 | A randomized comparison of indwelling pleural catheter and doxycycline pleurodesis in the management of malignant pleural effusions | Cancer | 1999 | 362 |
| 5 | Ebola and Marburg Viruses Replicate in Monocyte‐Derived Dendritic Cells without Inducing the Production of Cytokines and Full Maturation | Journal of Infectious Diseases | 2003 | 268 |
| 6 | Coronary Artery Calcification and Risk of Cardiovascular Disease and Death Among Patients With Chronic Kidney Disease | JAMA Cardiology | 2017 | 251 |
| 7 | Genetic Epidemiology of Obesity | Epidemiologic Reviews | 2007 | 237 |
| 8 | The pathogenesis of heartburn in nonerosive reflux disease: A unifying hypothesis | Gastroenterology | 2005 | 228 |
| 9 | AKI and Collapsing Glomerulopathy Associated with COVID-19 and APOL 1 High-Risk Genotype | Journal of the American Society of Nephrology: JASN | 2020 | 204 |
| 10 | Pituitary Adenylate Cyclase Activating Polypeptide: A Potential Neuroprotective Peptide | Current Pharmaceutical Design | 2004 | 195 |
| 11 | The George Fahr Lecture | Circulation | 1952 | 179 |
| 12 | INTRAVENTRICULARLY INJECTED GROWTH HORMONE STIMULATES SOMATOSTATIN RELEASE INTO RAT HYPOPHYSIAL PORTAL BLOOD | Endocrinology | 1981 | 173 |
| 13 | Depth and durability of response to ibrutinib in CLL: 5-year follow-up of a phase 2 study | Blood | 2018 | 166 |
| 14 | Effect of coenzyme Q10 supplementation on heart failure: a meta-analysis | American Journal of Clinical Nutrition | 2013 | 158 |
| 15 | Detection of retroviral antibodies in primary biliary cirrhosis and other idiopathic biliary disorders | Lancet, The | 1998 | 154 |
| 16 | An in Vivo Model for Elucidation of the Mechanism of Tumor Necrosis Factor-α (TNF-α)-Induced Insulin Resistance: Evidence for Differential Regulation of Insulin Signaling by TNF-α | Endocrinology | 1998 | 143 |
| 17 | Principles and characteristics of food allergens | Critical Reviews in Food Science and Nutrition | 1996 | 141 |
| 18 | Differences in Gastric Carcinoma Microenvironment Stratify According to EBV Infection Intensity: Implications for Possible Immune Adjuvant Therapy | PLoS Pathogens | 2013 | 140 |
| 19 | Oncogenic HER2Δ16 suppresses miR-15a/16 and deregulates BCL-2 to promote endocrine resistance of breast tumors | Carcinogenesis | 2010 | 137 |
| 20 | Localization of Endomorphin-2-Like Immunoreactivity in the Rat Medulla and Spinal Cord | Peptides | 1997 | 136 |
| 21 | Prevalence, awareness, treatment and control of hypertension in North America, North Africa and Asia | Journal of Human Hypertension | 2004 | 133 |
| 22 | Endocrine Disruptor Regulation of MicroRNA Expression in Breast Carcinoma Cells | PLoS ONE | 2012 | 128 |
| 23 | Emphysematous Lesions, Inflammation, and Fibrosis in the Lungs of Transgenic Mice Overexpressing Platelet-Derived Growth Factor | American Journal of Pathology | 1999 | 125 |
| 24 | The role of pepsin in acid injury to esophageal epithelium | American Journal of Gastroenterology | 2001 | 124 |
| 25 | Blood Pressure and Risk of All-Cause Mortality in Advanced Chronic Kidney Disease and Hemodialysis | Hypertension | 2015 | 122 |
| 26 | Effect of dietary fiber intake on blood pressure | Journal of Hypertension | 2004 | 108 |
| 27 | Therapeutic Approaches to Target Inflammation in Type 2 Diabetes | Clinical Chemistry | 2011 | 102 |
| 28 | The Yeast Retrograde Response as a Model of Intracellular Signaling of Mitochondrial Dysfunction | Frontiers in Physiology | 2012 | 98 |
| 29 | Ovarian cancers overexpress the antimicrobial protein hCAP‐18 and its derivative LL‐37 increases ovarian cancer cell proliferation and invasion | International Journal of Cancer | 2008 | 96 |
| 30 | Sex Differences in Barriers to Antihypertensive Medication Adherence: Findings from the Cohort Study of Medication Adherence Among Older Adults | Journal of the American Geriatrics Society | 2013 | 96 |
| 31 | Serum Antioxidant Vitamins and Blood Pressure in the United States Population | Hypertension | 2002 | 94 |
| 32 | Brain pathologies in extreme old age | Neurobiology of Aging | 2016 | 94 |
| 33 | Trends in Incidence of Early-Onset Colorectal Cancer in the United States Among Those Approaching Screening Age | JAMA Network Open | 2020 | 92 |
| 34 | HBV and HIV Coinfection and Liver Transplant | American Journal of Transplantation | 2010 | 89 |
| 35 | The addition of androgen deprivation therapy and pelvic lymph node treatment to prostate bed salvage radiotherapy (NRG Oncology/RTOG 0534 SPPORT): an international, multicentre, randomised phase 3 trial | Lancet, The | 2022 | 89 |
| 36 | Prevention of bleeds in hemophilia patients with inhibitors: Emerging data and clinical direction | American Journal of Hematology | 2004 | 86 |
| 37 | Dual regulation by microRNA-200b-3p and microRNA-200b-5p in the inhibition of epithelial-to-mesenchymal transition in triple-negative breast cancer | Oncotarget | 2015 | 86 |
| 38 | THE OXIDATION OF GLYCOLIC ACID BY A LIVER ENZYME | Journal of Biological Chemistry | 1954 | 86 |
| 39 | Association of Urinary Biomarkers of Inflammation, Injury, and Fibrosis with Renal Function Decline: The ACCORD Trial | Clinical Journal of the American Society of Nephrology: CJASN | 2016 | 85 |
| 40 | Impaired estrogen receptor action in the pathogenesis of the metabolic syndrome | Molecular and Cellular Endocrinology | 2015 | 84 |
| 41 | Transport of NH3/NH 4 + in oocytes expressing aquaporin-1 | American Journal of Physiology - Renal Physiology | 2001 | 83 |
| 42 | A CD19/CD3 bispecific antibody for effective immunotherapy of chronic lymphocytic leukemia in the ibrutinib era | Blood | 2018 | 81 |
| 43 | Augmentation of Pituitary Responsiveness to LH-Releasing Hormone (LH-RH) by Estrogen | Experimental Biology and Medicine | 1971 | 79 |
| 44 | Loss of Mitochondrial Membrane Potential Triggers the Retrograde Response Extending Yeast Replicative Lifespan | Frontiers in Genetics | 2011 | 78 |
| 45 | Association of Urinary Oxalate Excretion With the Risk of Chronic Kidney Disease Progression | JAMA Internal Medicine | 2019 | 78 |
| 46 | Engineering Breast Cancer Microenvironments and 3D Bioprinting | Frontiers in Bioengineering and Biotechnology | 2018 | 77 |
| 47 | Lead Nephropathy, Gout, and Hypertension | American Journal of the Medical Sciences | 1993 | 76 |
| 48 | Repository corticotropin for Chronic Pulmonary Sarcoidosis | Lung | 2017 | 75 |
| 49 | Studies on the Mechanism of Growth Hormone and Thyrotropin Responses to Somatostatin Antiserum in Anesthetized Rats* | Endocrinology | 1978 | 74 |
| 50 | Efficacy and safety of nebivolol and valsartan as fixed-dose combination in hypertension: a randomised, multicentre study | Lancet, The | 2014 | 71 |
