# | Title | Journal | Year | Citations |
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1 | The plant immune system | Nature | 2006 | 10,939 |
2 | Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 | Cell Death and Differentiation | 2018 | 4,036 |
3 | Diversity and heritability of the maize rhizosphere microbiome under field conditions | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 1,594 |
4 | The Inflammasome NLRs in Immunity, Inflammation, and Associated Diseases | Annual Review of Immunology | 2011 | 1,411 |
5 | The MKK2 Pathway Mediates Cold and Salt Stress Signaling in Arabidopsis | Molecular Cell | 2004 | 859 |
6 | The NLR Gene Family: A Standard Nomenclature | Immunity | 2008 | 761 |
7 | Overexpression of TGFα in transgenic mice: Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast | Cell | 1990 | 726 |
8 | Cutting Edge: Inflammasome Activation by Alum and Alum’s Adjuvant Effect Are Mediated by NLRP3 | Journal of Immunology | 2008 | 591 |
9 | Cord blood NK cells engineered to express IL-15 and a CD19-targeted CAR show long-term persistence and potent antitumor activity | Leukemia | 2018 | 525 |
10 | Autophagy Links Inflammasomes to Atherosclerotic Progression | Cell Metabolism | 2012 | 509 |
11 | RNA motif discovery by SHAPE and mutational profiling (SHAPE-MaP) | Nature Methods | 2014 | 487 |
12 | Interleukin-1β Promotes Repair of the CNS | Journal of Neuroscience | 2001 | 464 |
13 | Replicon-Helper Systems from Attenuated Venezuelan Equine Encephalitis Virus: Expression of Heterologous Genesin Vitroand Immunization against Heterologous Pathogensin Vivo | Virology | 1997 | 416 |
14 | Signal Transduction via the Multi-Step Phosphorelay: Not Necessarily a Road Less Traveled | Cell | 1996 | 414 |
15 | Induction of Tumor Cell Apoptosis In Vivo Increases Tumor Antigen Cross-Presentation, Cross-Priming Rather than Cross-Tolerizing Host Tumor-Specific CD8 T Cells | Journal of Immunology | 2003 | 401 |
16 | CAR T Cells Administered in Combination with Lymphodepletion and PD-1 Inhibition to Patients with Neuroblastoma | Molecular Therapy | 2017 | 378 |
17 | The antifolding activity of SecB promotes the export of the E. coli maltose-binding protein | Cell | 1988 | 366 |
18 | Complete mutagenesis of the HIV-1 protease | Nature | 1989 | 357 |
19 | TROSPA, an Ixodes scapularis Receptor for Borrelia burgdorferi | Cell | 2004 | 348 |
20 | Expanded functions for a family of plant intracellular immune receptors beyond specific recognition of pathogen effectors | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 346 |
21 | NLRP3 Plays a Critical Role in the Development of Experimental Autoimmune Encephalomyelitis by Mediating Th1 and Th17 Responses | Journal of Immunology | 2010 | 345 |
22 | Severe Acute Respiratory Syndrome Coronavirus Papain-Like Protease Ubiquitin-Like Domain and Catalytic Domain Regulate Antagonism of IRF3 and NF-κB Signaling | Journal of Virology | 2009 | 325 |
23 | CATERPILLER: A Novel Gene Family Important in Immunity, Cell Death, and Diseases | Annual Review of Immunology | 2005 | 321 |
24 | A simple, rapid method for the purification of poly A+ RNA | BioTechniques | 1988 | 313 |
25 | The Human Antibody Response to Dengue Virus Infection | Viruses | 2011 | 296 |
26 | B Cells and T Follicular Helper Cells Mediate Response to Checkpoint Inhibitors in High Mutation Burden Mouse Models of Breast Cancer | Cell | 2019 | 291 |
27 | A new member of the leucine zipper class of proteins that binds to the HLA DR alpha promoter | Science | 1990 | 287 |
28 | Brassinosteroids modulate the efficiency of plant immune responses to microbe-associated molecular patterns | Proceedings of the National Academy of Sciences of the United States of America | 2012 | 287 |
29 | Synapsis of DNA ends by DNA-dependent protein kinase | EMBO Journal | 2002 | 286 |
30 | Therapeutic B cell depletion impairs adaptive and autoreactive CD4+T cell activation in mice | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 282 |
31 | The covalently closed duplex form of the hepadnavirus genome exists in situ as a heterogeneous population of viral minichromosomes | Journal of Virology | 1995 | 282 |
32 | Cutting Edge: CATERPILLER: A Large Family of Mammalian Genes Containing CARD, Pyrin, Nucleotide-Binding, and Leucine-Rich Repeat Domains | Journal of Immunology | 2002 | 272 |
33 | In vitro–differentiated TH17 cells mediate lethal acute graft-versus-host disease with severe cutaneous and pulmonary pathologic manifestations | Blood | 2009 | 272 |
34 | Antigenic and genetic heterogeneity of Borrelia burgdorferi populations transmitted by ticks | Proceedings of the National Academy of Sciences of the United States of America | 2001 | 270 |
35 | Purified secB protein of Escherichia coli retards folding and promotes membrane translocation of the maltose-binding protein in vitro. | Proceedings of the National Academy of Sciences of the United States of America | 1988 | 264 |
36 | The Inflammasome Sensor, NLRP3, Regulates CNS Inflammation and Demyelination via Caspase-1 and Interleukin-18 | Journal of Neuroscience | 2010 | 263 |
37 | Host genetic diversity enables Ebola hemorrhagic fever pathogenesis and resistance | Science | 2014 | 262 |
38 | The pathogenic role of the inflammasome in neurodegenerative diseases | Journal of Neurochemistry | 2016 | 253 |
39 | The Pseudomonas syringae effector AvrRpt2 cleaves its C-terminally acylated target, RIN4, from Arabidopsis membranes to block RPM1 activation | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 250 |
40 | Resistance to Antimalarials in Southeast Asia and Genetic Polymorphisms in pfmdr1 | Antimicrobial Agents and Chemotherapy | 2003 | 245 |
41 | Cellular and Humoral Immunity following Snow Mountain Virus Challenge | Journal of Virology | 2005 | 236 |
42 | Transgenic Expression of IL15 Improves Antiglioma Activity of IL13Rα2-CAR T Cells but Results in Antigen Loss Variants | Cancer Immunology Research | 2017 | 232 |
43 | A novel receptor tyrosine kinase, Mer, inhibits TNF-alpha production and lipopolysaccharide-induced endotoxic shock | Journal of Immunology | 1999 | 232 |
44 | Parkinson’s disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures | Journal of Neural Transmission | 2011 | 230 |
45 | Immune and histopathological responses in animals vaccinated with recombinant vaccinia viruses that express individual genes of human respiratory syncytial virus | Journal of Virology | 1987 | 229 |
46 | Expression and processing of the AIDS virus reverse transcriptase in Escherichia coli | Science | 1987 | 227 |
47 | bZIP10-LSD1 antagonism modulates basal defense and cell death in Arabidopsis following infection | EMBO Journal | 2006 | 225 |
48 | NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth | Nature Immunology | 2017 | 225 |
49 | Human Coronavirus HKU1 Spike Protein Uses O -Acetylated Sialic Acid as an Attachment Receptor Determinant and Employs Hemagglutinin-Esterase Protein as a Receptor-Destroying Enzyme | Journal of Virology | 2015 | 218 |
50 | Bacterial adaptation to oxidative stress: implications for pathogenesis and interaction with phagocytic cells | FASEB Journal | 1989 | 217 |