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Top Articles

#TitleJournalYearCitations
1The plant immune systemNature200610,939
2Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018Cell Death and Differentiation20184,036
3Diversity and heritability of the maize rhizosphere microbiome under field conditionsProceedings of the National Academy of Sciences of the United States of America20131,594
4The Inflammasome NLRs in Immunity, Inflammation, and Associated DiseasesAnnual Review of Immunology20111,411
5The MKK2 Pathway Mediates Cold and Salt Stress Signaling in ArabidopsisMolecular Cell2004859
6The NLR Gene Family: A Standard NomenclatureImmunity2008761
7Overexpression of TGFα in transgenic mice: Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breastCell1990726
8Cutting Edge: Inflammasome Activation by Alum and Alum’s Adjuvant Effect Are Mediated by NLRP3Journal of Immunology2008591
9Cord blood NK cells engineered to express IL-15 and a CD19-targeted CAR show long-term persistence and potent antitumor activityLeukemia2018525
10Autophagy Links Inflammasomes to Atherosclerotic ProgressionCell Metabolism2012509
11RNA motif discovery by SHAPE and mutational profiling (SHAPE-MaP)Nature Methods2014487
12Interleukin-1β Promotes Repair of the CNSJournal of Neuroscience2001464
13Replicon-Helper Systems from Attenuated Venezuelan Equine Encephalitis Virus: Expression of Heterologous Genesin Vitroand Immunization against Heterologous Pathogensin VivoVirology1997416
14Signal Transduction via the Multi-Step Phosphorelay: Not Necessarily a Road Less TraveledCell1996414
15Induction of Tumor Cell Apoptosis In Vivo Increases Tumor Antigen Cross-Presentation, Cross-Priming Rather than Cross-Tolerizing Host Tumor-Specific CD8 T CellsJournal of Immunology2003401
16CAR T Cells Administered in Combination with Lymphodepletion and PD-1 Inhibition to Patients with NeuroblastomaMolecular Therapy2017378
17The antifolding activity of SecB promotes the export of the E. coli maltose-binding proteinCell1988366
18Complete mutagenesis of the HIV-1 proteaseNature1989357
19TROSPA, an Ixodes scapularis Receptor for Borrelia burgdorferiCell2004348
20Expanded functions for a family of plant intracellular immune receptors beyond specific recognition of pathogen effectorsProceedings of the National Academy of Sciences of the United States of America2011346
21NLRP3 Plays a Critical Role in the Development of Experimental Autoimmune Encephalomyelitis by Mediating Th1 and Th17 ResponsesJournal of Immunology2010345
22Severe Acute Respiratory Syndrome Coronavirus Papain-Like Protease Ubiquitin-Like Domain and Catalytic Domain Regulate Antagonism of IRF3 and NF-κB SignalingJournal of Virology2009325
23CATERPILLER: A Novel Gene Family Important in Immunity, Cell Death, and DiseasesAnnual Review of Immunology2005321
24A simple, rapid method for the purification of poly A+ RNABioTechniques1988313
25The Human Antibody Response to Dengue Virus InfectionViruses2011296
26B Cells and T Follicular Helper Cells Mediate Response to Checkpoint Inhibitors in High Mutation Burden Mouse Models of Breast CancerCell2019291
27A new member of the leucine zipper class of proteins that binds to the HLA DR alpha promoterScience1990287
28Brassinosteroids modulate the efficiency of plant immune responses to microbe-associated molecular patternsProceedings of the National Academy of Sciences of the United States of America2012287
29Synapsis of DNA ends by DNA-dependent protein kinaseEMBO Journal2002286
30Therapeutic B cell depletion impairs adaptive and autoreactive CD4+T cell activation in miceProceedings of the National Academy of Sciences of the United States of America2007282
31The covalently closed duplex form of the hepadnavirus genome exists in situ as a heterogeneous population of viral minichromosomesJournal of Virology1995282
32Cutting Edge: CATERPILLER: A Large Family of Mammalian Genes Containing CARD, Pyrin, Nucleotide-Binding, and Leucine-Rich Repeat DomainsJournal of Immunology2002272
33In vitro–differentiated TH17 cells mediate lethal acute graft-versus-host disease with severe cutaneous and pulmonary pathologic manifestationsBlood2009272
34Antigenic and genetic heterogeneity of Borrelia burgdorferi populations transmitted by ticksProceedings of the National Academy of Sciences of the United States of America2001270
35Purified secB protein of Escherichia coli retards folding and promotes membrane translocation of the maltose-binding protein in vitro.Proceedings of the National Academy of Sciences of the United States of America1988264
36The Inflammasome Sensor, NLRP3, Regulates CNS Inflammation and Demyelination via Caspase-1 and Interleukin-18Journal of Neuroscience2010263
37Host genetic diversity enables Ebola hemorrhagic fever pathogenesis and resistanceScience2014262
38The pathogenic role of the inflammasome in neurodegenerative diseasesJournal of Neurochemistry2016253
39The Pseudomonas syringae effector AvrRpt2 cleaves its C-terminally acylated target, RIN4, from Arabidopsis membranes to block RPM1 activationProceedings of the National Academy of Sciences of the United States of America2005250
40Resistance to Antimalarials in Southeast Asia and Genetic Polymorphisms in pfmdr1Antimicrobial Agents and Chemotherapy2003245
41Cellular and Humoral Immunity following Snow Mountain Virus ChallengeJournal of Virology2005236
42Transgenic Expression of IL15 Improves Antiglioma Activity of IL13Rα2-CAR T Cells but Results in Antigen Loss VariantsCancer Immunology Research2017232
43A novel receptor tyrosine kinase, Mer, inhibits TNF-alpha production and lipopolysaccharide-induced endotoxic shockJournal of Immunology1999232
44Parkinson’s disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structuresJournal of Neural Transmission2011230
45Immune and histopathological responses in animals vaccinated with recombinant vaccinia viruses that express individual genes of human respiratory syncytial virusJournal of Virology1987229
46Expression and processing of the AIDS virus reverse transcriptase in Escherichia coliScience1987227
47bZIP10-LSD1 antagonism modulates basal defense and cell death in Arabidopsis following infectionEMBO Journal2006225
48NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growthNature Immunology2017225
49Human Coronavirus HKU1 Spike Protein Uses O -Acetylated Sialic Acid as an Attachment Receptor Determinant and Employs Hemagglutinin-Esterase Protein as a Receptor-Destroying EnzymeJournal of Virology2015218
50Bacterial adaptation to oxidative stress: implications for pathogenesis and interaction with phagocytic cellsFASEB Journal1989217