# | Title | Journal | Year | Citations |
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1 | Dupilumab progressively improves systemic and cutaneous abnormalities in patients with atopic dermatitis | Journal of Allergy and Clinical Immunology | 2019 | 436 |
2 | Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population | Nature Genetics | 2012 | 310 |
3 | The Harmonising Outcome Measures for Eczema (HOME) statement to assess clinical signs of atopic eczema in trials | Journal of Allergy and Clinical Immunology | 2014 | 257 |
4 | Guidelines for management of atopic dermatitis | Journal of Dermatology | 2009 | 215 |
5 | Differential role of MAPK signaling in human dendritic cell maturation and Th1/Th2 engagement | Journal of Dermatological Science | 2006 | 210 |
6 | Atopic dermatitis: immune deviation, barrier dysfunction, IgE autoreactivity and new therapies | Allergology International | 2017 | 202 |
7 | Nemolizumab in patients with moderate-to-severe atopic dermatitis: Randomized, phase II, long-term extension study | Journal of Allergy and Clinical Immunology | 2018 | 195 |
8 | The Harmonizing Outcome Measures for Eczema (HOME) Roadmap: A Methodological Framework to Develop Core Sets of Outcome Measurements in Dermatology | Journal of Investigative Dermatology | 2015 | 184 |
9 | Regulation of Filaggrin, Loricrin, and Involucrin by IL-4, IL-13, IL-17A, IL-22, AHR, and NRF2: Pathogenic Implications in Atopic Dermatitis | International Journal of Molecular Sciences | 2020 | 181 |
10 | Towards global consensus on outcome measures for atopic eczema research: results of the HOME II meeting | Allergy: European Journal of Allergy and Clinical Immunology | 2012 | 169 |
11 | The first trial of CIM331, a humanized antihuman interleukin-31 receptor A antibody, in healthy volunteers and patients with atopic dermatitis to evaluate safety, tolerability and pharmacokinetics of a single dose in a randomized, double-blind, placebo-co | British Journal of Dermatology | 2016 | 157 |
12 | Clinical dose and adverse effects of topical steroids in daily management of atopic dermatitis | British Journal of Dermatology | 2003 | 155 |
13 | STAT3-dependent reactive astrogliosis in the spinal dorsal horn underlies chronic itch | Nature Medicine | 2015 | 154 |
14 | An environmental contaminant, benzo(a)pyrene, induces oxidative stress-mediated interleukin-8 production in human keratinocytes via the aryl hydrocarbon receptor signaling pathway | Journal of Dermatological Science | 2011 | 150 |
15 | Identification of Ketoconazole as an AhR-Nrf2 Activator in Cultured Human Keratinocytes: The Basis of Its Anti-Inflammatory Effect | Journal of Investigative Dermatology | 2012 | 140 |
16 | Clinical Practice Guidelines for the Management of Atopic Dermatitis 2016 | Journal of Dermatology | 2016 | 140 |
17 | Cytokines and chemokines in the epidermis | Journal of Dermatological Science | 2000 | 135 |
18 | Role of AhR/ARNT system in skin homeostasis | Archives of Dermatological Research | 2014 | 135 |
19 | Interleukin-17A and Keratinocytes in Psoriasis | International Journal of Molecular Sciences | 2020 | 134 |
20 | Clinical and mycological spectra of Wangiella dermatitidis infections* | Mycoses | 1993 | 125 |
21 | Phase 2a, randomized, double‐blind, placebo‐controlled, multicenter, parallel‐group study of a H4R‐antagonist (JNJ‐39758979) in Japanese adults with moderate atopic dermatitis | Journal of Dermatology | 2015 | 120 |
22 | Role of c-Jun N-terminal kinase on lipopolysaccharide induced maturation of human monocyte-derived dendritic cells | International Immunology | 2004 | 118 |
23 | Report from the fourth international consensus meeting to harmonize core outcome measures for atopic eczema/dermatitis clinical trials (HOME initiative) | British Journal of Dermatology | 2016 | 115 |
24 | Gene regulation of filaggrin and other skin barrier proteins via aryl hydrocarbon receptor | Journal of Dermatological Science | 2015 | 112 |
25 | Aryl Hydrocarbon Receptor in Atopic Dermatitis and Psoriasis | International Journal of Molecular Sciences | 2019 | 112 |
26 | Japanese guidelines for atopic dermatitis 2020 | Allergology International | 2020 | 108 |
27 | Ceramidase Activity in Bacterial Skin Flora as a Possible Cause of Ceramide Deficiency in Atopic Dermatitis | Vaccine Journal | 1999 | 104 |
28 | Combination of patch test and IgE for dust mite antigens differentiates 130 patients with atopic dermatitis into four groups | Journal of the American Academy of Dermatology | 1992 | 103 |
29 | Aryl hydrocarbon receptor activation restores filaggrin expression via OVOL1 in atopic dermatitis | Cell Death and Disease | 2017 | 102 |
30 | Spindle Cell Hemangioendothelioma Exhibits the Ultrastructural Features of Reactive Vascular Proliferation Rather than of Angiosarcoma | American Journal of Clinical Pathology | 1992 | 100 |
31 | Cytokine biomarkers to predict antitumor responses to nivolumab suggested in a phase 2 study for advanced melanoma | Cancer Science | 2017 | 100 |
32 | Cyclophosphamide enhances immunity by modulating the balance of dendritic cell subsets in lymphoid organs | Blood | 2010 | 98 |
33 | Novel Strategy for Soft Tissue Augmentation Based on Transplantation of Fragmented Omentum and Preadipocytes | Tissue Engineering | 2004 | 97 |
34 | Prenatal exposure to PCDDs/PCDFs and dioxin-like PCBs in relation to birth weight | Environmental Research | 2009 | 97 |
35 | Report from the fifth international consensus meeting to harmonize core outcome measures for atopic eczema/dermatitis clinical trials (HOME initiative) | British Journal of Dermatology | 2018 | 96 |
36 | Anti-PD1 checkpoint inhibitor therapy in acral melanoma: a multicenter study of 193 Japanese patients | Annals of Oncology | 2020 | 96 |
37 | beta-Catenin mutation and its nuclear localization are confirmed to be frequent causes of Wnt signaling pathway activation in pilomatricomas | Journal of Dermatological Science | 2006 | 90 |
38 | Circumscribed Dermal Melanoses: Classification and Histologic Features | Dermatologic Clinics | 1988 | 89 |
39 | The IL‐13/periostin/IL‐24 pathway causes epidermal barrier dysfunction in allergic skin inflammation | Allergy: European Journal of Allergy and Clinical Immunology | 2018 | 89 |
40 | Clinicopathological features of cutaneous lesions of adult T-cell leukaemia/ lymphoma | British Journal of Dermatology | 2005 | 87 |
41 | Clinical characteristics associated with BRAF, NRAS and KIT mutations in Japanese melanoma patients | Journal of Dermatological Science | 2015 | 87 |
42 | Beneficial effect of a diet containing heat-killed Lactobacillus paracasei K71 on adult type atopic dermatitis | Journal of Dermatology | 2011 | 86 |
43 | Antioxidants for Healthy Skin: The Emerging Role of Aryl Hydrocarbon Receptors and Nuclear Factor-Erythroid 2-Related Factor-2 | Nutrients | 2017 | 82 |
44 | Highlighting Interleukin-36 Signalling in Plaque Psoriasis and Pustular Psoriasis | Acta Dermato-Venereologica | 2018 | 81 |
45 | Regulation of Skin Barrier Function via Competition between AHR Axis versus IL-13/IL-4‒JAK‒STAT6/STAT3 Axis: Pathogenic and Therapeutic Implications in Atopic Dermatitis | Journal of Clinical Medicine | 2020 | 80 |
46 | Propionibacterium acnes-induced IL-8 production may be mediated by NF-κB activation in human monocytes | Journal of Dermatological Science | 2002 | 79 |
47 | Clinical practice guidelines for the management of atopic dermatitis 2018 | Journal of Dermatology | 2019 | 77 |
48 | LOCALIZATION OF HUMAN INTERLEUKIN 13 RECEPTOR IN NON-HAEMATOPOIETIC CELLS | Cytokine | 2001 | 76 |
49 | Efficacy and Safety of a Traditional Herbal Medicine,Hochu-ekki-toin the Long-Term Management ofKikyo(Delicate Constitution) Patients with Atopic Dermatitis: A 6-Month, Multicenter, Double-Blind, Randomized, Placebo-Controlled Study | Evidence-based Complementary and Alternative Medicine | 2010 | 75 |
50 | Arylhydrocarbon receptor (AhR) activation in airway epithelial cells induces MUC5AC via reactive oxygen species (ROS) production | Pulmonary Pharmacology and Therapeutics | 2011 | 75 |