| # | Title | Journal | Year | Citations |
|---|
| 1 | CDK inhibitors: positive and negative regulators of G1-phase progression | Genes and Development | 1999 | 5,227 |
| 2 | Cancer Cell Cycles | Science | 1996 | 4,932 |
| 3 | Inhibitors of mammalian G1 cyclin-dependent kinases. | Genes and Development | 1995 | 2,940 |
| 4 | G1 phase progression: Cycling on cue | Cell | 1994 | 2,668 |
| 5 | Mammalian G1 cyclins | Cell | 1993 | 1,994 |
| 6 | AML1, the Target of Multiple Chromosomal Translocations in Human Leukemia, Is Essential for Normal Fetal Liver Hematopoiesis | Cell | 1996 | 1,789 |
| 7 | The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF 1 | Cell | 1985 | 1,602 |
| 8 | Tumor Suppression at the Mouse INK4a Locus Mediated by the Alternative Reading Frame Product p19 ARF | Cell | 1997 | 1,519 |
| 9 | Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle | Cell | 1991 | 1,179 |
| 10 | Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4 | Genes and Development | 1993 | 1,144 |
| 11 | Functional interactions of the retinoblastoma protein with mammalian D-type cyclins | Cell | 1993 | 1,056 |
| 12 | Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization | Genes and Development | 1998 | 1,054 |
| 13 | The p21Cip1 and p27Kip1 CDK `inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts | EMBO Journal | 1999 | 989 |
| 14 | Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts. | Genes and Development | 1993 | 962 |
| 15 | The Pezcoller lecture: cancer cell cycles revisited | Cancer Research | 2000 | 907 |
| 16 | D-type cyclins | Trends in Biochemical Sciences | 1995 | 905 |
| 17 | The INK4a/ARF network in tumour suppression | Nature Reviews Molecular Cell Biology | 2001 | 890 |
| 18 | Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins | Cell | 1992 | 888 |
| 19 | Human aminopeptidase N is a receptor for human coronavirus 229E | Nature | 1992 | 843 |
| 20 | Forging a signature of in vivo senescence | Nature Reviews Cancer | 2015 | 775 |
| 21 | Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN | Nature Medicine | 2000 | 744 |
| 22 | Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27Kip1) of cyclin-dependent kinase 4 activation | Cell | 1994 | 741 |
| 23 | Cellular Senescence | Cell | 2000 | 720 |
| 24 | Targeting CDK4 and CDK6: From Discovery to Therapy | Cancer Discovery | 2016 | 717 |
| 25 | Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway. | Genes and Development | 1997 | 652 |
| 26 | A repeating amino acid motif shared by proteins with diverse cellular roles | Cell | 1994 | 643 |
| 27 | Tumor surveillance via the ARF–p53 pathway | Genes and Development | 1998 | 641 |
| 28 | The ARF/p53 pathway | Current Opinion in Genetics and Development | 2000 | 612 |
| 29 | Novel INK4 Proteins, p19 and p18, Are Specific Inhibitors of the Cyclin D-Dependent Kinases CDK4 and CDK6 | Molecular and Cellular Biology | 1995 | 607 |
| 30 | Two Distinct Stress Signaling Pathways Converge Upon the CHOP Promoter During the Mammalian Unfolded Protein Response | Journal of Molecular Biology | 2002 | 605 |
| 31 | Inhibition of Cyclin-Dependent Kinases by Purine Analogues | FEBS Journal | 1994 | 576 |
| 32 | Stat5 Is Required for IL-2-Induced Cell Cycle Progression of Peripheral T Cells | Immunity | 1999 | 530 |
| 33 | Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging | Oncogene | 1997 | 527 |
| 34 | Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1) | Proceedings of the National Academy of Sciences of the United States of America | 1998 | 489 |
| 35 | A Subset of Chaperones and Folding Enzymes Form Multiprotein Complexes in Endoplasmic Reticulum to Bind Nascent Proteins | Molecular Biology of the Cell | 2002 | 481 |
| 36 | Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and protein-protein interactions. | Molecular and Cellular Biology | 1993 | 469 |
| 37 | Identification of a new catenin: the tyrosine kinase substrate p120cas associates with E-cadherin complexes. | Molecular and Cellular Biology | 1994 | 457 |
| 38 | The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and a novel nuclear pore component Nup88 | EMBO Journal | 1997 | 441 |
| 39 | BiP Maintains the Permeability Barrier of the ER Membrane by Sealing the Lumenal End of the Translocon Pore before and Early in Translocation | Cell | 1998 | 395 |
| 40 | ERK Activation Mediates Cell Cycle Arrest and Apoptosis after DNA Damage Independently of p53 | Journal of Biological Chemistry | 2002 | 381 |
| 41 | Transforming potential of the c-fms proto-oncogene (CSF-1 receptor) | Nature | 1987 | 370 |
| 42 | The t(8;21) Fusion Protein Interferes with AML-1B-Dependent Transcriptional Activation | Molecular and Cellular Biology | 1995 | 369 |
| 43 | The Unfolding Tale of the Unfolded Protein Response | Cell | 2001 | 369 |
| 44 | p53-independent functions of the p19ARF tumor suppressor | Genes and Development | 2000 | 317 |
| 45 | Colony-stimulating factor-1 receptor | Blood | 1990 | 303 |
| 46 | Regulation of cyclin D-dependent kinase 4 (cdk4) by cdk4-activating kinase. | Molecular and Cellular Biology | 1994 | 297 |
| 47 | Tumor spectrum in ARF-deficient mice | Cancer Research | 1999 | 281 |
| 48 | A genome-editing strategy to treat β-hemoglobinopathies that recapitulates a mutation associated with a benign genetic condition | Nature Medicine | 2016 | 279 |
| 49 | The INK4 family of cell cycle inhibitors in cancer | Oncogene | 1999 | 277 |
| 50 | Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia | Nature Genetics | 2001 | 268 |
